2020

Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, Jagadeesh Reddy PB, Kasturi SP, Tsai A, Yeung BZ, Gupta S, Tomai M, Vasilakos J, Shaw GM, Kang CY, Moore JP, Subramaniam S, Khatri P, Montefiori D, Kozlowski PA, Derdeyn CA, Hunter E, Masopust D, Amara RR, Pulendran B
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lowerneutralizing antibody titers.
Nat Med. 2020 May 11. pii: 10.1038/s41591-020-0858-8. doi:10.1038/s41591-020-0858-8. 2020.

Bauer AM, Ziani W, Lindemuth E, Kuri-Cervantes L, Li H, Lee FH, Watkins M, Xu H, Veazey R, Bar KJ
Novel transmitted/founder SHIVs for HIV latency and cure research.
J Virol. 2020 Jan 22. pii: JVI.01659-19. doi: 10.1128/JVI.01659-19. 2020.

Estep RD, Govindan AN, Manoharan M, Li H, Fei SS, Park BS, Axthelm MK, Wong SW
Molecular analysis of lymphoid tissue from rhesus macaque rhadinovirus-infectedmonkeys identifies alterations in host genes associated with oncogenesis.
PLoS One. 2020 Feb 4;15(2):e0228484. doi: 10.1371/journal.pone.0228484.eCollection 2020. 2020.

Felber BK, Lu Z, Hu X, Valentin A, Rosati M, Remmel CAL, Weiner JA, Carpenter MC, Faircloth K, Stanfield-Oakley S, Williams WB, Shen X, Tomaras GD, LaBranche CC, Montefiori D, Trinh HV, Rao M, Alam MS, Vandergrift NA, Saunders KO, Wang Y, Rountree W, Das J, Alter G, Reed SG, Aye PP, Schiro F, Pahar B, Dufour JP, Veazey RS, Marx PA, Venzon DJ, Shaw GM, Ferrari G, Ackerman ME, Haynes BF, Pavlakis GN
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.
Cell Rep. 2020 May 12;31(6):107624. doi: 10.1016/j.celrep.2020.107624. 2020.

Fuchs SP, Martinez-Navio JM, Rakasz EG, Gao G, Desrosiers RC
Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys.
Mol Ther Methods Clin Dev. 2019 Nov 26;16:94-102. doi:10.1016/j.omtm.2019.11.010. eCollection 2020 Mar 13. 2020.

Ganatra SR, Bucsan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish AI, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, Rengarajan J, Kaushal D
Anti-retroviral therapy does not reduce tuberculosis reactivation in atuberculosis-HIV co-infection model.
J Clin Invest. 2020 Jun 16. pii: 136502. doi: 10.1172/JCI136502. 2020.

Gary E, O'Connor M, Chakhtoura M, Tardif V, Kumova OK, Malherbe DC, Sutton WF, Haigwood NL, Kutzler MA, Haddad EK
Adenosine deaminase-1 enhances germinal center formation and functional antibody responses to HIV-1 Envelope DNA and protein vaccines.
Vaccine. 2020 Apr 9. pii: S0264-410X(20)30436-9. doi:10.1016/j.vaccine.2020.03.047. 2020.

Harper J, Gordon S, Chan CN, Wang H, Lindemuth E, Galardi C, Falcinelli SD, Raines SLM, Read JL, Nguyen K, McGary CS, Nekorchuk M, Busman-Sahay K, Schawalder J, King C, Pino M, Micci L, Cervasi B, Jean S, Sanderson A, Johns B, Koblansky AA, Amrine-Madsen H, Lifson J, Margolis DM, Silvestri G, Bar KJ, Favre D, Estes JD, Paiardini M
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of reboundafter antiretroviral therapy interruption.
Nat Med. 2020 Apr;26(4):519-528. doi: 10.1038/s41591-020-0782-y. Epub 2020 Mar16. 2020.

Joas S, Sauermann U, Roshani B, Klippert A, Daskalaki M, Matz-Rensing K, Stolte-Leeb N, Heigele A, Tharp GK, Gupta PM, Nelson S, Bosinger S, Parodi L, Giavedoni L, Silvestri G, Sauter D, Stahl-Hennig C, Kirchhoff F
Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIVImmune Evasion.
Cell Rep. 2020 Feb 18;30(7):2261-2274.e7. doi: 10.1016/j.celrep.2020.01.069. 2020.

Lee CA, Beasley E, Sundar K, Smelkinson M, Vinton C, Deleage C, Matsuda K, Wu F, Estes JD, Lafont BAP, Brenchley JM, Hirsch VM
Simian Immunodeficiency Virus-Infected Memory CD4(+) T Cells Infiltrate to theSite of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS.
mBio. 2020 Apr 21;11(2). pii: mBio.00602-20. doi: 10.1128/mBio.00602-20. 2020.

Ma L, Chen Z, Huang DW, Cisse OH, Rothenburger JL, Latinne A, Bishop L, Blair R, Brenchley JM, Chabe M, Deng X, Hirsch V, Keesler R, Kutty G, Liu Y, Margolis D, Morand S, Pahar B, Peng L, Van Rompay KKA, Song X, Song J, Sukura A, Thapar S, Wang H, Weissenbacher-Lang C, Xu J, Lee CH, Jardine C, Lempicki RA, Cushion MT, Cuomo CA, Kovacs JA
Diversity and Complexity of the Large Surface Protein Family in the CompactedGenomes of Multiple Pneumocystis Species.
mBio. 2020 Mar 3;11(2). pii: mBio.02878-19. doi: 10.1128/mBio.02878-19. 2020.

Malherbe DC, Wibmer CK, Nonyane M, Reed J, Sather DN, Spencer DA, Schuman JT, Guo B, Pandey S, Robins H, Park B, Fuller DH, Sacha JB, Moore PL, Hessell AJ, Haigwood NL
Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development.
Front Immunol. 2020 Jun 2;11:984. doi: 10.3389/fimmu.2020.00984. eCollection2020. 2020.

Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A
Correction for Mavigner et al., 'Simian Immunodeficiency Virus Persistence inCellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques'.
J Virol. 2020 Mar 31;94(8). pii: 94/8/e01742-19. doi: 10.1128/JVI.01742-19. Print2020 Mar 31. 2020.

McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Suhay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G
Robust and persistent reactivation of SIV and HIV by N-803 and depletion ofCD8(+) cells.
Nature. 2020 Jan 22. pii: 10.1038/s41586-020-1946-0. doi:10.1038/s41586-020-1946-0. 2020.

Obregon-Perko V, Bricker K, Chahroudi A
The Brain Retains: Nonhuman Primate Models for Pediatric HIV-1 in the CNS.
Curr HIV/AIDS Rep. 2020 May 10. pii: 10.1007/s11904-020-00503-4. doi:10.1007/s11904-020-00503-4. 2020.

Pedreno-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, Wrammert J, Rakasz EG, Lifson JD, Martins MA, Burton DR, Watkins DI, Magnani DM
Induction of Transient Virus Replication Facilitates Antigen-IndependentIsolation of SIV-Specific Monoclonal Antibodies.
Mol Ther Methods Clin Dev. 2020 Feb 13;16:225-237. doi:10.1016/j.omtm.2020.01.010. eCollection 2020 Mar 13. 2020.

Shapiro MB, Cheever T, Malherbe DC, Pandey S, Reed J, Yang ES, Wang K, Pegu A, Chen X, Siess D, Burke D, Henderson H, Lewinsohn R, Fischer M, Stanton JJ, Axthelm MK, Kahl C, Park B, Lewis AD, Sacha JB, Mascola JR, Hessell AJ, Haigwood NL
Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tightSHIV control without adaptive immunity.
Nat Commun. 2020 Jan 7;11(1):70. doi: 10.1038/s41467-019-13972-y. 2020.

Sharan R, Bucsan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D
Chronic Immune Activation in TB/HIV Co-infection.
Trends Microbiol. 2020 Apr 22. pii: S0966-842X(20)30086-X. doi:10.1016/j.tim.2020.03.015. 2020.

Tavakoli-Tameh A, Janaka SK, Zarbock K, O'Connor S, Crosno K, Capuano S 3rd, Uno H, Lifson JD, Evans DT
Loss of tetherin antagonism by Nef impairs SIV replication during acute infectionof rhesus macaques.
PLoS Pathog. 2020 Apr 17;16(4):e1008487. doi: 10.1371/journal.ppat.1008487. 2020.

Thippeshappa R, Kimata JT, Kaushal D
Toward a Macaque Model of HIV-1 Infection: Roadblocks, Progress, and FutureStrategies.
Front Microbiol. 2020 May 13;11:882. doi: 10.3389/fmicb.2020.00882. eCollection2020. 2020.

Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM, Garber M, Deeks SG, Luban J
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expandTCF7-dependent memory NK cells.
Nat Immunol. 2020 Mar;21(3):274-286. doi: 10.1038/s41590-020-0593-9. Epub 2020Feb 17. 2020.

Webb GM, Molden J, Busman-Sahay K, Abdulhaqq S, Wu HL, Weber WC, Bateman KB, Reed JS, Northrup M, Maier N, Tanaka S, Gao L, Davey B, Carpenter BL, Axthelm MK, Stanton JJ, Smedley J, Greene JM, Safrit JT, Estes JD, Skinner PJ, Sacha JB
The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ Tand NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.
PLoS Pathog. 2020 Mar 12;16(3):e1008339. doi: 10.1371/journal.ppat.1008339.eCollection 2020 Mar. 2020.

2019

Bar KJ, Coronado E, Hensley-McBain T, O'Connor MA, Osborn JM, Miller C, Gott TM, Wangari S, Iwayama N, Ahrens CY, Smedley J, Moats C, Lynch RM, Haddad EK, Haigwood NL, Fuller DH, Shaw GM, Klatt NR, Manuzak JA
Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus MacaquesResults in Persistent Viral Replication and Induces Intestinal Immunopathology.
J Virol. 2019 Aug 28;93(18). pii: JVI.00372-19. doi: 10.1128/JVI.00372-19. Print 2019 Sep 15. 2019.

Barrenas F, Raehtz K, Xu C, Law L, Green RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang J, Smith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr
Macrophage-associated wound healing contributes to African green monkey SIVpathogenesis control.
Nat Commun. 2019 Nov 8;10(1):5101. doi: 10.1038/s41467-019-12987-9. 2019.

Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF
The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2Infections.
Cell Host Microbe. 2019 Jul 10;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005. 2019.

Bohannon DG, Ko A, Filipowicz AR, Kuroda MJ, Kim WK
Dysregulation of sonic hedgehog pathway and pericytes in the brain afterlentiviral infection.
J Neuroinflammation. 2019 Apr 13;16(1):86. doi: 10.1186/s12974-019-1463-y. 2019.

Bucsan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D
Mechanisms of reactivation of latent tuberculosis infection due to SIVcoinfection.
J Clin Invest. 2019 Oct 28. pii: 125810. doi: 10.1172/JCI125810. 2019.

Burton S, Spicer LM, Charles TP, Gangadhara S, Reddy PBJ, Styles TM, Velu V, Kasturi SP, Legere T, Hunter E, Pulendran B, Amara R, Hraber P, Derdeyn CA
Clade C HIV-1 Envelope Vaccination Regimens Differ in Their Ability To ElicitAntibodies with Moderate Neutralization Breadth against Genetically Diverse Tier 2 HIV-1 Envelope Variants.
J Virol. 2019 Mar 21;93(7). pii: JVI.01846-18. doi: 10.1128/JVI.01846-18. Print2019 Apr 1. 2019.

Calenda G, Frank I, Arrode-Bruses G, Pegu A, Wang K, Arthos J, Cicala C, Rogers KA, Shirreff L, Grasperge B, Blanchard JL, Maldonado S, Roberts K, Gettie A, Villinger F, Fauci AS, Mascola JR, Martinelli E
Delayed vaginal SHIV infection in VRC01 and anti-alpha4beta7 treated rhesusmacaques.
PLoS Pathog. 2019 May 13;15(5):e1007776. doi: 10.1371/journal.ppat.1007776.eCollection 2019 May. 2019.

Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR
Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccineefficacy.
Sci Transl Med. 2019 Nov 20;11(519). pii: 11/519/eaav1800. doi:10.1126/scitranslmed.aav1800. 2019.

Chea LS, Wyatt LS, Gangadhara S, Moss B, Amara RR
Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13RDelays Apoptosis and Enhances Humoral Responses.
J Virol. 2019 Feb 19;93(5). pii: JVI.01648-18. doi: 10.1128/JVI.01648-18. Print2019 Mar 1. 2019.

Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis.
Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021. 2019.

Curtis AD 2nd, Walter KA, Nabi R, Jensen K, Dwivedi A, Pollara J, Ferrari G, Van Rompay KKA, Amara RR, Kozlowski PA, De Paris K
Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccinefor Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques.
AIDS Res Hum Retroviruses. 2019 Mar;35(3):310-325. doi: 10.1089/AID.2018.0180.Epub 2018 Nov 27. 2019.

Delery E, Bohannon DG, Irons DL, Allers C, Sugimoto C, Cai Y, Merino KM, Amedee AM, Veazey RS, MacLean A, Kuroda MJ, Kim WK
Lack of susceptibility in neonatally infected rhesus macaques to simianimmunodeficiency virus-induced encephalitis.
J Neurovirol. 2019 Aug;25(4):578-588. doi: 10.1007/s13365-019-00755-w. Epub 2019 May 22. 2019.

Delery EC, MacLean AG
Chronic Viral Neuroinflammation: Speculation on Underlying Mechanisms.
Viral Immunol. 2019 Jan/Feb;32(1):55-62. doi: 10.1089/vim.2018.0093. Epub 2018Sep 27. 2019.

Elizaldi SR, Verma A, Walter KA, Rolston M, Dinasarapu AR, Durbin-Johnson BP, Settles M, Kozlowski PA, Raeman R, Iyer SS
Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 inVaccinated Rhesus Macaques.
mSphere. 2019 Dec 11;4(6). pii: 4/6/e00824-19. doi: 10.1128/mSphere.00824-19. 2019.

Foreman TW, Bucsan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacteriumtuberculosis in Macaques.
Am J Respir Crit Care Med. 2019 Oct 24. doi: 10.1164/rccm.201903-0646OC. 2019.

Frank I, Acharya A, Routhu NK, Aravantinou M, Harper JL, Maldonado S, Sole Cigoli M, Semova S, Mazel S, Paiardini M, Derby N, Byrareddy SN, Martinelli E
A Tat/Rev Induced Limiting Dilution Assay to Measure Viral Reservoirs inNon-Human Primate Models of HIV Infection.
Sci Rep. 2019 Aug 19;9(1):12078. doi: 10.1038/s41598-019-48354-3. 2019.

Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, Farzan M
AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239challenges.
Sci Transl Med. 2019 Jul 24;11(502). pii: 11/502/eaau5409. doi:10.1126/scitranslmed.aau5409. 2019.

Gerlach SL, Chandra PK, Roy U, Gunasekera S, Goransson U, Wimley WC, Braun SE, Mondal D
The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously TargetsHIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.
Medicines (Basel). 2019 Feb 28;6(1). pii: medicines6010033. doi:10.3390/medicines6010033. 2019.

Gonzalez-Nieto L, Castro IM, Bischof GF, Shin YC, Ricciardi MJ, Bailey VK, Dang CM, Pedreno-Lopez N, Magnani DM, Ejima K, Allison DB, Gil HM, Evans DT, Rakasz EG, Lifson JD, Desrosiers RC, Martins MA
Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
PLoS Pathog. 2019 Sep 30;15(9):e1008015. doi: 10.1371/journal.ppat.1008015.eCollection 2019 Sep. 2019.

Goswami R, Nelson AN, Tu JJ, Dennis M, Feng L, Kumar A, Mangold J, Mangan RJ, Mattingly C, Curtis AD 2nd, Obregon-Perko V, Mavigner M, Pollara J, Shaw GM, Bar KJ, Chahroudi A, De Paris K, Chan C, Van Rompay KKA, Permar SR
Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in aPostnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.
MBio. 2019 Sep 5;10(5). pii: mBio.01971-19. doi: 10.1128/mBio.01971-19. 2019.

Hahn AS, Bischof GF, Grosskopf AK, Shin YC, Domingues A, Gonzalez-Nieto L, Rakasz EG, Watkins DI, Ensser A, Martins MA, Desrosiers RC
A Recombinant Rhesus Monkey Rhadinovirus Deleted of Glycoprotein L EstablishesPersistent Infection of Rhesus Macaques and Elicits Conventional T Cell Responses.
J Virol. 2019 Oct 23. pii: JVI.01093-19. doi: 10.1128/JVI.01093-19. 2019.

Hansen SG, Marshall EE, Malouli D, Ventura AB, Hughes CM, Ainslie E, Ford JC, Morrow D, Gilbride RM, Bae JY, Legasse AW, Oswald K, Shoemaker R, Berkemeier B, Bosche WJ, Hull M, Womack J, Shao J, Edlefsen PT, Reed JS, Burwitz BJ, Sacha JB, Axthelm MK, Fruh K, Lifson JD, Picker LJ
A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologousSIV challenge.
Sci Transl Med. 2019 Jul 17;11(501). pii: 11/501/eaaw2607. doi:10.1126/scitranslmed.aaw2607. 2019.

Hessell AJ, Powell R, Jiang X, Luo C, Weiss S, Dussupt V, Itri V, Fox A, Shapiro MB, Pandey S, Cheever T, Fuller DH, Park B, Krebs SJ, Totrov M, Haigwood NL, Kong XP, Zolla-Pazner S
Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially TunePolyfunctional Antibody Responses.
Cell Rep. 2019 Jul 23;28(4):877-895.e6. doi: 10.1016/j.celrep.2019.06.074. 2019.

Hoang TN, Harper JL, Pino M, Wang H, Micci L, King CT, McGary CS, McBrien JB, Cervasi B, Silvestri G, Paiardini M
Bone Marrow-Derived CD4(+) T Cells Are Depleted in Simian ImmunodeficiencyVirus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir.
J Virol. 2018 Dec 10;93(1). pii: JVI.01344-18. doi: 10.1128/JVI.01344-18. Print2019 Jan 1. 2019.

Hoang TN, Paiardini M
Role of cytokine agonists and immune checkpoint inhibitors toward HIV remission.
Curr Opin HIV AIDS. 2019 Mar;14(2):121-128. doi: 10.1097/COH.0000000000000528. 2019.

Hueber B, Curtis AD 2nd, Kroll K, Varner V, Jones R, Pathak S, Lifton M, Van Rompay KKA, De Paris K, Reeves RK
Functional perturbation of mucosal group 3 innate lymphoid and natural killercells in SHIV/SIV-infected infant rhesus macaques.
J Virol. 2019 Dec 4. pii: JVI.01644-19. doi: 10.1128/JVI.01644-19. 2019.

Jones AT, Shen X, Walter KL, LaBranche CC, Wyatt LS, Tomaras GD, Montefiori DC, Moss B, Barouch DH, Clements JD, Kozlowski PA, Varadarajan R, Amara RR
HIV-1 vaccination by needle-free oral injection induces strong mucosal immunityand protects against SHIV challenge.
Nat Commun. 2019 Feb 18;10(1):798. doi: 10.1038/s41467-019-08739-4. 2019.

Khanal S, Fennessey CM, O'Brien SP, Thorpe A, Reid C, Immonen TT, Smith R, Bess JW Jr, Swanstrom AE, Del Prete GQ, Davenport MP, Okoye AA, Picker LJ, Lifson JD, Keele BF
In vivo validation of the viral barcoding of SIVmac239 and the development of newbarcoded SIV and subtype B and C SHIVs.
J Virol. 2019 Oct 9. pii: JVI.01420-19. doi: 10.1128/JVI.01420-19. 2019.

Kumar V, Torben W, Mansfield J, Alvarez X, Vande Stouwe C, Li J, Byrareddy SN, Didier PJ, Pahar B, Molina PE, Mohan M
Cannabinoid Attenuation of Intestinal Inflammation in Chronic SIV-Infected RhesusMacaques Involves T Cell Modulation and Differential Expression of Micro-RNAs and Pro-inflammatory Genes.
Front Immunol. 2019 Apr 30;10:914. doi: 10.3389/fimmu.2019.00914. eCollection2019. 2019.

Lo M, Zhu J, Hansen SG, Carroll T, Farr Zuend C, Noel-Romas L, Ma ZM, Fritts L, Huang ML, Sun S, Huang Y, Koelle DM, Picker LJ, Burgener A, Corey L, Miller CJ
Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2after Vaginal Inoculation of Rhesus Macaques.
J Virol. 2019 Jan 4;93(2). pii: JVI.01574-18. doi: 10.1128/JVI.01574-18. Print2019 Jan 15. 2019.

Markowitz M, Gettie A, St Bernard L, Andrews CD, Mohri H, Horowitz A, Grasperge BF, Blanchard JL, Niu T, Sun L, Fillgrove K, Hazuda DJ, Grobler JA
Title: Once-weekly Oral Dosing of MK-8591 Protects Male Rhesus Macaques fromIntrarectal SHIV109CP3 Challenge.
J Infect Dis. 2019 Jun 7. pii: 5513016. doi: 10.1093/infdis/jiz271. 2019.

Marshall EE, Malouli D, Hansen SG, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Selseth AN, Ford JC, Burke D, Kreklywich CN, Womack J, Legasse AW, Axthelm MK, Kahl C, Streblow D, Edlefsen PT, Picker LJ, Fruh K
Enhancing safety of cytomegalovirus-based vaccine vectors by engaging hostintrinsic immunity.
Sci Transl Med. 2019 Jul 17;11(501). pii: 11/501/eaaw2603. doi:10.1126/scitranslmed.aaw2603. 2019.

Martinez-Navio JM, Fuchs SP, Pantry SN, Lauer WA, Duggan NN, Keele BF, Rakasz EG, Gao G, Lifson JD, Desrosiers RC
Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can DriveLong-Term Virologic Suppression.
Immunity. 2019 Mar 19;50(3):567-575.e5. doi: 10.1016/j.immuni.2019.02.005. Epub2019 Mar 5. 2019.

Martins MA, Gonzalez-Nieto L, Shin YC, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Pedreno-Lopez N, Bailey VK, Altman JD, Parks CL, Allison DB, Ejima K, Rakasz EG, Capuano S 3rd, Desrosiers RC, Lifson JD, Watkins DI
The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate ofAcquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08(+) Rhesus Macaques.
J Virol. 2019 Feb 19;93(5). pii: JVI.01626-18. doi: 10.1128/JVI.01626-18. Print2019 Mar 1. 2019.

Matchett WE, Anguiano-Zarate SS, Nehete PN, Shelton K, Nehete BP, Yang G, Dorta-Estremera S, Barnette P, Xiao P, Byrareddy SN, Villinger F, Hessell AJ, Haigwood NL, Sastry KJ, Barry MA
Divergent HIV-1-Directed Immune Responses Generated by Systemic and MucosalImmunization with Replicating Single-Cycle Adenoviruses in Rhesus Macaques.
J Virol. 2019 May 1;93(10). pii: JVI.02016-18. doi: 10.1128/JVI.02016-18. Print2019 May 15. 2019.

Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A
Correction for Mavigner et al., 'Simian Immunodeficiency Virus Persistence inCellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques'.
J Virol. 2019 Jan 17;93(3). pii: 93/3/e01814-18. doi: 10.1128/JVI.01814-18. Print2019 Feb 1. 2019.

Mavigner M, Zanoni M, Tharp GK, Habib J, Mattingly CR, Lichterfeld M, Nega MT, Vanderford TH, Bosinger SE, Chahroudi A
Pharmacological modulation of the Wnt/beta-catenin pathway inhibits proliferationand promotes differentiation of long-lived memory CD4(+) T-cells in ART-suppressed SIV-infected macaques.
J Virol. 2019 Oct 16. pii: JVI.01094-19. doi: 10.1128/JVI.01094-19. 2019.

McQueen P, Busman-Sahay K, Rieder F, Noel-Romas L, McCorrister S, Westmacott G, Estes JD, Burgener A
Intestinal proteomic analysis of a novel non-human primate model of experimental colitis reveals signatures of mitochondrial and metabolic dysfunction.
Mucosal Immunol. 2019 Sep 3. pii: 10.1038/s41385-019-0200-2. doi:10.1038/s41385-019-0200-2. 2019.

Morou A, Brunet-Ratnasingham E, Dube M, Charlebois R, Mercier E, Darko S, Brassard N, Nganou-Makamdop K, Arumugam S, Gendron-Lepage G, Yang L, Niessl J, Baxter AE, Billingsley JM, Rajakumar PA, Lefebvre F, Johnson RP, Tremblay C, Routy JP, Wyatt RT, Finzi A, Douek DC, Kaufmann DE
Altered differentiation is central to HIV-specific CD4(+) T cell dysfunction inprogressive disease.
Nat Immunol. 2019 Aug;20(8):1059-1070. doi: 10.1038/s41590-019-0418-x. Epub 2019 Jul 15. 2019.

Murugesan A, Ibegbu C, Styles TM, Jones AT, Shanmugasundaram U, Reddy PBJ, Rahman SJ, Saha P, Vijay-Kumar M, Shankar EM, Amara RR, Velu V
Functional MAIT Cells Are Associated With Reduced Simian-Human ImmunodeficiencyVirus Infection.
Front Immunol. 2020 Jan 17;10:3053. doi: 10.3389/fimmu.2019.03053. eCollection2019. 2019.

Nelson AN, Goswami R, Dennis M, Tu J, Mangan RJ, Saha PT, Cain DW, Curtis AD, Shen X, Shaw GM, Bar K, Hudgens M, Pollara J, De Paris K, Van Rompay KKA, Permar SR
Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult RhesusMacaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.
J Virol. 2019 Jul 17;93(15). pii: JVI.00168-19. doi: 10.1128/JVI.00168-19. Print 2019 Aug 1. 2019.

O'Connor MA, Munson PV, Tunggal HC, Hajari N, Lewis TB, Bratt D, Moats C, Smedley J, Bagley KC, Mullins JI, Fuller DH
Mucosal T Helper 17 and T Regulatory Cell Homeostasis Correlate with Acute SimianImmunodeficiency Virus Viremia and Responsiveness to Antiretroviral Therapy in Macaques.
AIDS Res Hum Retroviruses. 2019 Mar;35(3):295-305. doi: 10.1089/AID.2018.0184.Epub 2019 Jan 2. 2019.

Okoye AA, DeGottardi MQ, Fukazawa Y, Vaidya M, Abana CO, Konfe AL, Fachko DN, Duell DM, Li H, Lum R, Gao L, Park BS, Skalsky RL, Lewis AD, Axthelm MK, Lifson JD, Wong SW, Picker LJ
Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency VirusInfection in Rhesus Macaques.
J Immunol. 2019 Oct 25. pii: jimmunol.1900792. doi: 10.4049/jimmunol.1900792. 2019.

Pahar B, Kuebler D, Rasmussen T, Wang X, Srivastav SK, Das A, Veazey RS
Quantification of Viral RNA and DNA Positive Cells in Tissues From SimianImmunodeficiency Virus/Simian Human Immunodeficiency Virus Infected Controller and Progressor Rhesus Macaques.
Front Microbiol. 2019 Dec 20;10:2933. doi: 10.3389/fmicb.2019.02933. eCollection 2019. 2019.

Pan D, Das A, Srivastav SK, Traina-Dorge V, Didier PJ, Pahar B
Lack of T-cell-mediated IL-2 and TNFalpha production is linked to decreased CD58 expression in intestinal tissue during acute simian immunodeficiency virus infection.
J Gen Virol. 2019 Jan;100(1):26-34. doi: 10.1099/jgv.0.001181. Epub 2018 Nov 29. 2019.

Pegu A, Borate B, Huang Y, Pauthner MG, Hessell AJ, Julg B, Doria-Rose NA, Schmidt SD, Carpp LN, Cully MD, Chen X, Shaw GM, Barouch DH, Haigwood NL, Corey L, Burton DR, Roederer M, Gilbert PB, Mascola JR, Huang Y
A Meta-analysis of Passive Immunization Studies Shows that Serum-NeutralizingAntibody Titer Associates with Protection against SHIV Challenge.
Cell Host Microbe. 2019 Sep 11;26(3):336-346.e3. doi: 10.1016/j.chom.2019.08.014. 2019.

Peterson TA, MacLean AG
Current and Future Therapeutic Strategies for Lentiviral Eradication fromMacrophage Reservoirs.
J Neuroimmune Pharmacol. 2019 Mar;14(1):68-93. doi: 10.1007/s11481-018-9814-5.Epub 2018 Oct 13. 2019.

Petitdemange C, Kasturi SP, Kozlowski PA, Nabi R, Quarnstrom CF, Reddy PBJ, Derdeyn CA, Spicer LM, Patel P, Legere T, Kovalenkov YO, Labranche CC, Villinger F, Tomai M, Vasilakos J, Haynes B, Kang CY, Gibbs JS, Yewdell JW, Barouch D, Wrammert J, Montefiori D, Hunter E, Amara RR, Masopust D, Pulendran B
Vaccine induction of antibodies and tissue-resident CD8+ T cells enhancesprotection against mucosal SHIV-infection in young macaques.
JCI Insight. 2019 Feb 21;4(4). pii: 126047. doi: 10.1172/jci.insight.126047.eCollection 2019 Feb 21. 2019.

Rajawat YS, Humbert O, Kiem HP
In-Vivo Gene Therapy with Foamy Virus Vectors.
Viruses. 2019 Nov 23;11(12). pii: v11121091. doi: 10.3390/v11121091. 2019.

Styles TM, Gangadhara S, Reddy PBJ, Hicks S, LaBranche CC, Montefiori DC, Derdeyn CA, Kozlowski PA, Velu V, Amara RR
Human Immunodeficiency Virus C.1086 Envelope gp140 Protein Boosts followingDNA/Modified Vaccinia Virus Ankara Vaccination Fail To Enhance Heterologous Anti-V1V2 Antibody Response and Protection against Clade C Simian-Human Immunodeficiency Virus Challenge.
J Virol. 2019 Sep 30;93(20). pii: JVI.00934-19. doi: 10.1128/JVI.00934-19. Print 2019 Oct 15. 2019.

Sutton MS, Ellis-Connell A, Balgeman AJ, Barry G, Weiler AM, Hetzel SJ, Zhou Y, Lau-Kilby AW, Mason RD, Biris KK, Mascola JR, Sullivan NJ, Roederer M, Friedrich TC, O'Connor SL
CD8beta Depletion Does Not Prevent Control of Viral Replication or Protectionfrom Challenge in Macaques Chronically Infected with a Live Attenuated Simian Immunodeficiency Virus.
J Virol. 2019 Jul 17;93(15). pii: JVI.00537-19. doi: 10.1128/JVI.00537-19. Print 2019 Aug 1. 2019.

Swainson LA, Ahn H, Pajanirassa P, Khetarpal V, Deleage C, Estes JD, Hunt PW, Munoz-Sanjuan I, McCune JM
Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4(+) T Cell Counts and Body Weight.
J Immunol. 2019 Aug 15;203(4):899-910. doi: 10.4049/jimmunol.1801649. Epub 2019Jul 8. 2019.

Takahashi N, Sugimoto C, Allers C, Alvarez X, Kim WK, Didier ES, Kuroda MJ
Shifting Dynamics of Intestinal Macrophages during Simian Immunodeficiency Virus Infection in Adult Rhesus Macaques.
J Immunol. 2019 May 1;202(9):2682-2689. doi: 10.4049/jimmunol.1801457. Epub 2019 Mar 29. 2019.

Thompson CG, Rosen EP, Prince HMA, White N, Sykes C, de la Cruz G, Mathews M, Deleage C, Estes JD, Charlins P, Mulder LR, Kovarova M, Adamson L, Arora S, Dellon ES, Peery AF, Shaheen NJ, Gay C, Muddiman DC, Akkina R, Garcia JV, Luciw P, Kashuba ADM
Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species.
Sci Transl Med. 2019 Jul 3;11(499). pii: 11/499/eaap8758. doi:10.1126/scitranslmed.aap8758. 2019.

Van Rompay KKA, Hassounah S, Keele BF, Lifson JD, Ardeshir A, Watanabe J, Pham HT, Chertova E, Sowder R, Balzarini J, Mesplede T, Wainberg MA
Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected MacaquesSelects for Several Patterns of Resistance Mutations with Variable Virological Outcomes.
J Virol. 2019 Jan 4;93(2). pii: JVI.01189-18. doi: 10.1128/JVI.01189-18. Print2019 Jan 15. 2019.

von Bredow B, Andrabi R, Grunst M, Grandea AG 3rd, Le K, Song G, Berndsen ZT, Porter K, Pallesen J, Ward AB, Burton DR, Evans DT
Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for theSIVsmm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization.
MBio. 2019 Jul 2;10(4). pii: mBio.01255-19. doi: 10.1128/mBio.01255-19. 2019.

Wang X, Russell-Lodrigue KE, Ratterree MS, Veazey RS, Xu H
Chemokine receptor CCR5 correlates with functional CD8(+) T cells in SIV-infectedmacaques and the potential effects of maraviroc on T-cell activation.
FASEB J. 2019 Aug;33(8):8905-8912. doi: 10.1096/fj.201802703R. Epub 2019 Apr 29. 2019.

Wood MP, Wood LF, Templeton M, Fisher B, Lippy A, Jones CI, Lindestam Arlehamn CS, Sette A, Fuller JT, Murapa P, Jaspan HB, Fuller DH, Sodora DL
Transient Immune Activation in BCG-Vaccinated Infant Rhesus Macaques Is NotSufficient to Influence Oral Simian Immunodeficiency Virus Infection.
J Infect Dis. 2019 Oct 12. pii: 5586557. doi: 10.1093/infdis/jiz382. 2019.

Zhou M, Humbert M, Mukhtar MM, Scinto HB, Vyas HK, Lakhashe SK, Byrareddy SN, Maurer G, Thorat S, Owuor J, Lai Z, Chen Y, Griffiths A, Chenine AL, Gumber S, Villinger F, Montefiori D, Ruprecht RM
Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade AEnvelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants.
J Virol. 2019 Apr 17;93(9). pii: JVI.02267-18. doi: 10.1128/JVI.02267-18. Print2019 May 1. 2019.

2018

Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC
Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines inSHIVnef-Infected Macaques.
Viral Immunol. 2018 Apr;31(3):206-222. doi: 10.1089/vim.2017.0051. Epub 2017 Dec 19. 2018.

Amedee AM, Phillips B, Jensen K, Robichaux S, Lacour N, Burke M, Piatak M Jr, Lifson JD, Kozlowski PA, Van Rompay KKA, De Paris K
Early Sites of Virus Replication After Oral SIVmac251 Infection of InfantMacaques: Implications for Pathogenesis.
AIDS Res Hum Retroviruses. 2018 Mar;34(3):286-299. doi: 10.1089/AID.2017.0169.Epub 2018 Jan 17. 2018.

Bosinger SE, Tharp GK, Patel NB, Zhao C, Payne TL, Dietz Ostergaard S, Butler K, Ellis S, Johnson RL, Kersh EN, McNicholl JM, Vishwanathan SA
Progestin-based contraception regimens modulate expression of putative HIV riskfactors in the vaginal epithelium of pig-tailed Macaques.
Am J Reprod Immunol. 2018 Oct;80(4):e13029. doi: 10.1111/aji.13029. Epub 2018 Aug3. 2018.

Bruce AG, Barcy S, Staheli J, Bielefeldt-Ohmann H, Ikoma M, Howard K, Rose TM
Experimental co-transmission of Simian Immunodeficiency Virus (SIV) and themacaque homologs of the Kaposi Sarcoma-Associated Herpesvirus (KSHV) and Epstein-Barr Virus (EBV).
PLoS One. 2018 Nov 16;13(11):e0205632. doi: 10.1371/journal.pone.0205632.eCollection 2018. 2018.

Cao Y, Cartwright EK, Silvestri G, Perelson AS
CD8+ lymphocyte control of SIV infection during antiretroviral therapy.
PLoS Pathog. 2018 Oct 11;14(10):e1007350. doi: 10.1371/journal.ppat.1007350.eCollection 2018 Oct. 2018.

Carnathan D, Lawson B, Yu J, Patel K, Billingsley JM, Tharp GK, Delmas OM, Dawoud R, Wilkinson P, Nicolette C, Cameron MJ, Sekaly RP, Bosinger SE, Silvestri G, Vanderford TH
Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
J Virol. 2018 Apr 13;92(9). pii: JVI.01760-17. doi: 10.1128/JVI.01760-17. Print2018 May 1. 2018.

Carnathan DG, Mackel JJ, Sweat SL, Enemuo CA, Gebru EH, Dhadvai P, Gangadhara S, Hicks S, Vanderford TH, Amara RR, Esparza J, Lu W, Andrieu JM, Silvestri G
Intragastric Administration of Lactobacillus plantarum and2,2'-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission.
J Virol. 2018 Apr 27;92(10). pii: JVI.02030-17. doi: 10.1128/JVI.02030-17. Print 2018 May 15. 2018.

Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE Jr
Increased breadth of HIV-1 neutralization achieved by diverse antibody cloneseach with limited neutralization breadth.
PLoS One. 2018 Dec 19;13(12):e0209437. doi: 10.1371/journal.pone.0209437.eCollection 2018. 2018.

Ciupe SM, Miller CJ, Forde JE
A Bistable Switch in Virus Dynamics Can Explain the Differences in DiseaseOutcome Following SIV Infections in Rhesus Macaques.
Front Microbiol. 2018 Jun 6;9:1216. doi: 10.3389/fmicb.2018.01216. eCollection2018. 2018.

Colonna L, Peterson CW, Schell JB, Carlson JM, Tkachev V, Brown M, Yu A, Reddy S, Obenza WM, Nelson V, Polacino PS, Mack H, Hu SL, Zeleski K, Hoffman M, Olvera J, Furlan SN, Zheng H, Taraseviciute A, Hunt DJ, Betz K, Lane JF, Vogel K, Hotchkiss CE, Moats C, Baldessari A, Murnane RD, English C, Astley CA, Wangari S, Agricola B, Ahrens J, Iwayama N, May A, Stensland L, Huang MW, Jerome KR, Kiem HP, Kean LS
Evidence for persistence of the SHIV reservoir early after MHC haploidenticalhematopoietic stem cell transplantation.
Nat Commun. 2018 Oct 25;9(1):4438. doi: 10.1038/s41467-018-06736-7. 2018.

Curtis AD 2nd, Jensen K, Van Rompay KKA, Amara RR, Kozlowski PA, De Paris K
A simultaneous oral and intramuscular prime/sublingual boost with a DNA/Modified Vaccinia Ankara viral vector-based vaccine induces simian immunodeficiency virus-specific systemic and mucosal immune responses in juvenile rhesus macaques.
J Med Primatol. 2018 Oct;47(5):288-297. doi: 10.1111/jmp.12372. Epub 2018 Sep 11. 2018.

Deleage C, Chan CN, Busman-Sahay K, Estes JD
Next-generation in situ hybridization approaches to define and quantify HIV andSIV reservoirs in tissue microenvironments.
Retrovirology. 2018 Jan 9;15(1):4. doi: 10.1186/s12977-017-0387-9. 2018.

Derby N, Lal M, Aravantinou M, Kizima L, Barnable P, Rodriguez A, Lai M, Wesenberg A, Ugaonkar S, Levendosky K, Mizenina O, Kleinbeck K, Lifson JD, Peet MM, Lloyd Z, Benson M, Heneine W, O'Keefe BR, Robbiani M, Martinelli E, Grasperge B, Blanchard J, Gettie A, Teleshova N, Fernandez-Romero JA, Zydowsky TM
Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPVinfections in vivo.
Nat Commun. 2018 Sep 24;9(1):3881. doi: 10.1038/s41467-018-06349-0. 2018.

Diepstra KL, Cunningham T, Rhodes AG, Yerkes LE, Buyu CA
Prevalence and Predictors of Provider-Initiated HIV Test Offers AmongHeterosexual Persons at Increased Risk for Acquiring HIV Infection - Virginia, 2016.
MMWR Morb Mortal Wkly Rep. 2018 Jun 29;67(25):714-717. doi:10.15585/mmwr.mm6725a3. 2018.

Dominguez-Molina B, Machmach K, Perales C, Tarancon-Diez L, Gallego I, Sheldon JL, Leal M, Domingo E, Ruiz-Mateos E
Toll-Like Receptor 7 (TLR-7) and TLR-9 Agonists Improve Hepatitis C VirusReplication and Infectivity Inhibition by Plasmacytoid Dendritic Cells.
J Virol. 2018 Nov 12;92(23). pii: JVI.01219-18. doi: 10.1128/JVI.01219-18. Print 2018 Dec 1. 2018.

Dufour JP, Russell-Lodrigue KE, Doyle-Meyers L, Falkenstein KP, Blair RV, Didier ES, Slisarenko N, Williams KC, Kuroda MJ
Hydrocephalus after Intrathecal Administration of Dextran to Rhesus Macaques(Macaca mulatta).
Comp Med. 2018 Jun 1;68(3):227-232. doi: 10.30802/AALAS-CM-17-000096. Epub 2018May 18. 2018.

Ellis-Connell AL, Balgeman AJ, Zarbock KR, Barry G, Weiler A, Egan JO, Jeng EK, Friedrich T, Miller JS, Haase AT, Schacker TW, Wong HC, Rakasz E, O'Connor SL
ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in theAbsence of Antiretroviral Treatment.
J Virol. 2018 Jan 17;92(3). pii: JVI.01748-17. doi: 10.1128/JVI.01748-17. Print2018 Feb 1. 2018.

Eudailey JA, Dennis ML, Parker ME, Phillips BL, Huffman TN, Bay CP, Hudgens MG, Wiseman RW, Pollara JJ, Fouda GG, Ferrari G, Pickup DJ, Kozlowski PA, Van Rompay KKA, De Paris K, Permar SR
Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To PreventOral SHIV Acquisition in Infant Macaques.
mSphere. 2018 Jan 10;3(1). pii: mSphere00505-17. doi: 10.1128/mSphere.00505-17.eCollection 2018 Jan-Feb. 2018.

Fisher BS, Green RR, Brown RR, Wood MP, Hensley-McBain T, Fisher C, Chang J, Miller AD, Bosche WJ, Lifson JD, Mavigner M, Miller CJ, Gale M Jr, Silvestri G, Chahroudi A, Klatt NR, Sodora DL
Liver macrophage-associated inflammation correlates with SIV burden and issubstantially reduced following cART.
PLoS Pathog. 2018 Feb 21;14(2):e1006871. doi: 10.1371/journal.ppat.1006871.eCollection 2018 Feb. 2018.

Ford SM Jr, Simon Peter L, Berner P, Cook G, Vande Stouwe C, Dufour J, Bagby G, Nelson S, Molina PE
Differential contribution of chronic binge alcohol and antiretroviral therapy to metabolic dysregulation in SIV-infected male macaques.
Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E892-E903. doi:10.1152/ajpendo.00175.2018. Epub 2018 Jul 24. 2018.

Gong S, Tomusange K, Kulkarni V, Adeniji OS, Lakhashe SK, Hariraju D, Strickland A, Plake E, Frost PA, Ratcliffe SJ, Wang L, Lafer EM, Ruprecht RM
Anti-HIV IgM protects against mucosal SHIV transmission.
AIDS. 2018 Jul 17;32(11):F5-F13. doi: 10.1097/QAD.0000000000001857. 2018.

Gumber S, Amancha PK, Yen PJ, Villinger F, Gabuzda D, Byrareddy SN
In vivo characterization of macrophage-tropic simian immunodeficiency virusmolecular clones in rhesus macaques.
J Neurovirol. 2018 Aug;24(4):411-419. doi: 10.1007/s13365-018-0628-2. Epub 2018Mar 28. 2018.

Haran KP, Hajduczki A, Pampusch MS, Mwakalundwa G, Vargas-Inchaustegui DA, Rakasz EG, Connick E, Berger EA, Skinner PJ
Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T CellsEngineered to Target B Cell Follicles and Suppress SIV Replication.
Front Immunol. 2018 Mar 20;9:492. doi: 10.3389/fimmu.2018.00492. eCollection2018. 2018.

Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge SF, Marx PA, Apetrei C, Kirchhoff F, Sauter D
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-MediatedCounteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.
J Virol. 2018 Aug 29;92(18). pii: JVI.00276-18. doi: 10.1128/JVI.00276-18. Print 2018 Sep 15. 2018.

Himes JE, Goswami R, Mangan RJ, Kumar A, Jeffries TL Jr, Eudailey JA, Heimsath H, Nguyen QN, Pollara J, LaBranche C, Chen M, Vandergrift NA, Peacock JW, Schiro F, Midkiff C, Ferrari G, Montefiori DC, Hernandez XA, Aye PP, Permar SR
Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIVacquisition and cell-associated virus loads in infant rhesus monkeys.
Mucosal Immunol. 2018 Nov;11(6):1716-1726. doi: 10.1038/s41385-018-0067-7. Epub2018 Aug 16. 2018.

Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, Chuenarom W, Burke R, Robb ML, Ndhlovu LC, Ananworanich J, Valcour V, O'Connell RJ, Spudich S, Michael NL, Vasan S
Central Nervous System Inflammation and Infection during Early, NonacceleratedSimian-Human Immunodeficiency Virus Infection in Rhesus Macaques.
J Virol. 2018 May 14;92(11). pii: JVI.00222-18. doi: 10.1128/JVI.00222-18. Print 2018 Jun 1. 2018.

Janaka SK, Tavakoli-Tameh A, Neidermyer WJ Jr, Serra-Moreno R, Hoxie JA, Desrosiers RC, Johnson RP, Lifson JD, Wolinsky SM, Evans DT
Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in AcuteViremia in Simian Immunodeficiency Virus Deltanef-Infected Animals.
J Virol. 2018 Oct 29;92(22). pii: JVI.00542-18. doi: 10.1128/JVI.00542-18. Print 2018 Nov 15. 2018.

Joas S, Parrish EH, Gnanadurai CW, Lump E, Sturzel CM, Parrish NF, Learn GH, Sauermann U, Neumann B, Rensing KM, Fuchs D, Billingsley JM, Bosinger SE, Silvestri G, Apetrei C, Huot N, Garcia-Tellez T, Muller-Trutwin M, Hotter D, Sauter D, Stahl-Hennig C, Hahn BH, Kirchhoff F
Species-specific host factors rather than virus-intrinsic virulence determineprimate lentiviral pathogenicity.
Nat Commun. 2018 Apr 10;9(1):1371. doi: 10.1038/s41467-018-03762-3. 2018.

Kumar NA, McBrien JB, Carnathan DG, Mavigner M, Mattingly C, White ER, Viviano F, Bosinger SE, Chahroudi A, Silvestri G, Paiardini M, Vanderford TH
Antibody-Mediated CD4 Depletion Induces Homeostatic CD4(+) T Cell Proliferationwithout Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques.
J Virol. 2018 Oct 29;92(22). pii: JVI.01235-18. doi: 10.1128/JVI.01235-18. Print 2018 Nov 15. 2018.

Kumar V, Mansfield J, Fan R, MacLean A, Li J, Mohan M
miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulationof PPARgamma and Occludin Expression in Chronic Simian Immunodeficiency Virus-Infected Rhesus Macaques.
J Immunol. 2018 Apr 15;200(8):2677-2689. doi: 10.4049/jimmunol.1701148. Epub 2018Mar 7. 2018.

Kuroda MJ, Sugimoto C, Cai Y, Merino KM, Mehra S, Arainga M, Roy CJ, Midkiff CC, Alvarez X, Didier ES, Kaushal D
High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation inSimian Immunodeficiency Virus-Infected Rhesus Macaques.
J Infect Dis. 2018 May 25;217(12):1865-1874. doi: 10.1093/infdis/jix625. 2018.

Lindgren AA, Filipowicz AR, Hattler JB, Kim SO, Chung HK, Kuroda MJ, Johnson EM, Kim WK
Lentiviral infection of proliferating brain macrophages in HIV and simianimmunodeficiency virus encephalitis despite sterile alpha motif and histidine-aspartate domain-containing protein 1 expression.
AIDS. 2018 May 15;32(8):965-974. doi: 10.1097/QAD.0000000000001793. 2018.

Malherbe DC, Mendy J, Vang L, Barnette PT, Reed J, Lakhashe SK, Owuor J, Gach JS, Legasse AW, Axthelm MK, LaBranche CC, Montefiori D, Forthal DN, Park B, Wilson JM, McLinden JH, Xiang J, Stapleton JT, Sacha JB, Haynes BF, Liao HX, Ruprecht RM, Smith J, Gurwith M, Haigwood NL, Alexander J
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce ViralBurden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge.
J Virol. 2018 Jan 2;92(2). pii: JVI.01092-17. doi: 10.1128/JVI.01092-17. Print2018 Jan 15. 2018.

Manuzak JA, Gott TM, Kirkwood JS, Coronado E, Hensley-McBain T, Miller C, Cheu RK, Collier AC, Funderburg NT, Martin JN, Wu MC, Isoherranen N, Hunt PW, Klatt NR
Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory ImmuneCell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals.
Clin Infect Dis. 2018 Jun 1;66(12):1872-1882. doi: 10.1093/cid/cix1116. 2018.

Marshall VA, Labo N, Hao XP, Holdridge B, Thompson M, Miley W, Brands C, Coalter V, Kiser R, Anver M, Golubeva Y, Warner A, Jaffe ES, Piatak M Jr, Wong SW, Ohlen C, MacAllister R, Smedley J, Deleage C, Del Prete GQ, Lifson JD, Estes JD, Whitby D
Gammaherpesvirus infection and malignant disease in rhesus macaquesexperimentally infected with SIV or SHIV.
PLoS Pathog. 2018 Jul 12;14(7):e1007130. doi: 10.1371/journal.ppat.1007130.eCollection 2018 Jul. 2018.

Martins MA, Tully DC, Pedreno-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S 3rd, Lifson JD, Desrosiers RC, Allen TM, Watkins DI
Mamu-B*17(+) Rhesus Macaques Vaccinated with env, vif, and nef Manifest EarlyControl of SIVmac239 Replication.
J Virol. 2018 Jul 31;92(16). pii: JVI.00690-18. doi: 10.1128/JVI.00690-18. Print 2018 Aug 15. 2018.

Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A
Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques.
J Virol. 2018 Aug 29;92(18). pii: JVI.00562-18. doi: 10.1128/JVI.00562-18. Print 2018 Sep 15. 2018.

McNamara RP, Costantini LM, Myers TA, Schouest B, Maness NJ, Griffith JD, Damania BA, MacLean AG, Dittmer DP
Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Humanand Simian Immunodeficiency Viruses.
MBio. 2018 Feb 6;9(1). pii: mBio.02344-17. doi: 10.1128/mBio.02344-17. 2018.

Mudd JC, Busman-Sahay K, DiNapoli SR, Lai S, Sheik V, Lisco A, Deleage C, Richardson B, Palesch DJ, Paiardini M, Cameron M, Sereti I, Reeves RK, Estes JD, Brenchley JM
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss ofinnate lymphoid cells.
Nat Commun. 2018 Sep 27;9(1):3967. doi: 10.1038/s41467-018-05528-3. 2018.

Munson P, Liu Y, Bratt D, Fuller JT, Hu X, Pavlakis GN, Felber BK, Mullins JI, Fuller DH
Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responsesagainst highly conserved viral sequences during simian-human immunodeficiency virus infection.
Hum Vaccin Immunother. 2018 Jul 3;14(7):1820-1831. doi:10.1080/21645515.2018.1448328. Epub 2018 Apr 12. 2018.

Obregon-Perko V, Hodara VL, Parodi LM, Giavedoni LD
Baboon CD8 T cells suppress SIVmac infection in CD4 T cells throughcontact-dependent production of MIP-1alpha, MIP-1beta, and RANTES.
Cytokine. 2018 Nov;111:408-419. doi: 10.1016/j.cyto.2018.05.022. Epub 2018 May26. 2018.

Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD
Early antiretroviral therapy limits SIV reservoir establishment to delay orprevent post-treatment viral rebound.
Nat Med. 2018 Sep;24(9):1430-1440. doi: 10.1038/s41591-018-0130-7. Epub 2018 Aug 6. 2018.

Palesch D, Bosinger SE, Mavigner M, Billingsley JM, Mattingly C, Carnathan DG, Paiardini M, Chahroudi A, Vanderford TH, Silvestri G
Short-Term Pegylated Interferon alpha2a Treatment Does Not Significantly Reducethe Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques.
J Virol. 2018 Jun 29;92(14). pii: JVI.00279-18. doi: 10.1128/JVI.00279-18. Print 2018 Jul 15. 2018.

Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB, Patel NB, Sodora DL, Dawoud RA, Stewart CB, Seepo SM, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G
Sooty mangabey genome sequence provides insight into AIDS resistance in a naturalSIV host.
Nature. 2018 Jan 3;553(7686):77-81. doi: 10.1038/nature25140. 2018.

Peterson CW, Wang J, Deleage C, Reddy S, Kaur J, Polacino P, Reik A, Huang ML, Jerome KR, Hu SL, Holmes MC, Estes JD, Kiem HP
Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.
PLoS Pathog. 2018 Apr 19;14(4):e1006956. doi: 10.1371/journal.ppat.1006956.eCollection 2018 Apr. 2018.

Rodgers MA, Ameel C, Ellis-Connell AL, Balgeman AJ, Maiello P, Barry GL, Friedrich TC, Klein E, O'Connor SL, Scanga CA
Preexisting Simian Immunodeficiency Virus Infection Increases Susceptibility toTuberculosis in Mauritian Cynomolgus Macaques.
Infect Immun. 2018 Nov 20;86(12). pii: IAI.00565-18. doi: 10.1128/IAI.00565-18.Print 2018 Dec. 2018.

Schwartz JA, Zhang H, Ende Z, Deymier MJ, Lee T, Singer J, Mazzulli T, Hunter E, Ostrowski MA
Characterization of the Plasmacytoid Dendritic Cell Response toTransmitted/Founder and Nontransmitted Variants of HIV-1.
J Virol. 2018 Sep 12;92(19). pii: JVI.00157-18. doi: 10.1128/JVI.00157-18. Print 2018 Oct 1. 2018.

Scinto HB, Gupta S, Thorat S, Mukhtar MM, Griffiths A, Delgado J, Plake E, Vyas HK, Strickland A, Byrareddy SN, Montefiori DC, LaBranche C, Pal R, Treece J, Orndorff S, Ferrari MG, Weiss D, Chenine AL, McLinden R, Michael N, Kim JH, Robb ML, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Ruprecht RM
Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying env from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.
J Virol. 2018 Jun 29;92(14). pii: JVI.02222-17. doi: 10.1128/JVI.02222-17. Print 2018 Jul 15. 2018.

Semler MR, Wiseman RW, Karl JA, Graham ME, Gieger SM, O'Connor DH
Novel full-length major histocompatibility complex class I allele discovery andhaplotype definition in pig-tailed macaques.
Immunogenetics. 2018 Jun;70(6):381-399. doi: 10.1007/s00251-017-1042-2. Epub 2017Nov 13. 2018.

Shah SV, Manickam C, Ram DR, Kroll K, Itell H, Permar SR, Barouch DH, Klatt NR, Reeves RK
CMV Primes Functional Alternative Signaling in Adaptive Deltag NK Cells but IsSubverted by Lentivirus Infection in Rhesus Macaques.
Cell Rep. 2018 Dec 4;25(10):2766-2774.e3. doi: 10.1016/j.celrep.2018.11.020. 2018.

Shang L, Smith AJ, Duan L, Perkey KE, Wietgrefe S, Zupancic M, Southern PJ, Johnson RP, Carlis JV, Haase AT
Vaccine-Associated Maintenance of Epithelial Integrity Correlated With ProtectionAgainst Virus Entry.
J Infect Dis. 2018 Sep 8;218(8):1272-1283. doi: 10.1093/infdis/jiy062. 2018.

Shin YC, Bischof GF, Lauer WA, Gonzalez-Nieto L, Rakasz EG, Hendricks GM, Watkins DI, Martins MA, Desrosiers RC
A recombinant herpesviral vector containing a near-full-length SIVmac239 genomeproduces SIV particles and elicits immune responses to all nine SIV gene products.
PLoS Pathog. 2018 Jun 18;14(6):e1007143. doi: 10.1371/journal.ppat.1007143.eCollection 2018 Jun. 2018.

Sutton MS, Ellis-Connell A, Moriarty RV, Balgeman AJ, Gellerup D, Barry G, Weiler AM, Friedrich TC, O'Connor SL
Acute-Phase CD4(+) T Cell Responses Targeting Invariant Viral Regions AreAssociated with Control of Live Attenuated Simian Immunodeficiency Virus.
J Virol. 2018 Oct 12;92(21). pii: JVI.00830-18. doi: 10.1128/JVI.00830-18. Print 2018 Nov 1. 2018.

Swanstrom AE, Del Prete GQ, Deleage C, Elser SE, Lackner AA, Hoxie JA
The SIV Envelope Glycoprotein, Viral Tropism, and Pathogenesis: Novel Insightsfrom Nonhuman Primate Models of AIDS.
Curr HIV Res. 2018;16(1):29-40. doi: 10.2174/1570162X15666171124123116. 2018.

Upadhyay AA, Kauffman RC, Wolabaugh AN, Cho A, Patel NB, Reiss SM, Havenar-Daughton C, Dawoud RA, Tharp GK, Sanz I, Pulendran B, Crotty S, Lee FE, Wrammert J, Bosinger SE
BALDR: a computational pipeline for paired heavy and light chain immunoglobulinreconstruction in single-cell RNA-seq data.
Genome Med. 2018 Mar 20;10(1):20. doi: 10.1186/s13073-018-0528-3. 2018.

Utay NS, Kitch DW, Yeh E, Fichtenbaum CJ, Lederman MM, Estes JD, Deleage C, Magyar C, Nelson SD, Klingman KL, Bastow B, Luque AE, McComsey GA, Douek DC, Currier JS, Lake JE
Telmisartan Therapy Does Not Improve Lymph Node or Adipose Tissue Fibrosis MoreThan Continued Antiretroviral Therapy Alone.
J Infect Dis. 2018 May 5;217(11):1770-1781. doi: 10.1093/infdis/jiy064. 2018.

Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, Stanton JJ, Legasse AW, Hobbs T, Martin LD, Park BS, Whitney JB, Jeng EK, Wong HC, Nixon DF, Jones RB, Connick E, Skinner PJ, Sacha JB
The human IL-15 superagonist ALT-803 directs SIV-specific CD8(+) T cells intoB-cell follicles.
Blood Adv. 2018 Jan 23;2(2):76-84. doi: 10.1182/bloodadvances.2017012971. 2018.

Xiao P, Gumber S, Marzinke MA, Date AA, Hoang T, Hanes J, Ensign LM, Wang L, Rohan L, Fuchs EJ, Hendrix C, Villinger F
Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection.
Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: AAC.01644-17. doi:10.1128/AAC.01644-17. Print 2018 Jan. 2018.

Xu H, Ziani W, Shao J, Doyle-Meyers LA, Russell-Lodrigue KE, Ratterree MS, Veazey RS, Wang X
Impaired Development and Expansion of Germinal Center Follicular Th Cells inSimian Immunodeficiency Virus-Infected Neonatal Macaques.
J Immunol. 2018 Oct 1;201(7):1994-2003. doi: 10.4049/jimmunol.1800235. Epub 2018 Aug 13. 2018.

2017

Aravantinou M, Frank I, Arrode-Bruses G, Szpara M, Grasperge B, Blanchard J, Gettie A, Derby N, Martinelli E
A model of genital herpes simplex virus Type 1 infection in Rhesus Macaques.
J Med Primatol. 2017 Aug;46(4):121-128. doi: 10.1111/jmp.12293. 2017.

Aravantinou M, Mizenina O, Calenda G, Kenney J, Frank I, Lifson JD, Szpara M, Jing L, Koelle DM, Teleshova N, Grasperge B, Blanchard J, Gettie A, Martinelli E, Derby N
Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in SimianImmunodeficiency Virus (SIV)-Infected Rhesus Macaques.
Front Microbiol. 2017 Dec 5;8:2342. doi: 10.3389/fmicb.2017.02342. eCollection2017. 2017.

Asmuth DM, Thompson CG, Chun TW, Ma ZM, Mann S, Sainz T, Serrano-Villar S, Utay NS, Garcia JC, Troia-Cancio P, Pollard RB, Miller CJ, Landay A, Kashuba AD
Tissue Pharmacologic and Virologic Determinants of Duodenal and RectalGastrointestinal-Associated Lymphoid Tissue Immune Reconstitution in HIV-Infected Patients Initiating Antiretroviral Therapy.
J Infect Dis. 2017 Oct 17;216(7):813-818. doi: 10.1093/infdis/jix418. 2017.

Bailey AL, Buechler CR, Matson DR, Peterson EJ, Brunner KG, Mohns MS, Breitbach M, Stewart LM, Ericsen AJ, Newman CM, Koenig MR, Mohr E, Tan J, Capuano S 3rd, Simmons HA, Yang DT, O'Connor DH
Pegivirus avoids immune recognition but does not attenuate acute-phase disease ina macaque model of HIV infection.
PLoS Pathog. 2017 Oct 26;13(10):e1006692. doi: 10.1371/journal.ppat.1006692.eCollection 2017 Oct. 2017.

Berg MR, Owston MA, Gauduin MC, Assaf BT, Lewis AD, Dick EJ Jr
Cytomegaloviral hypophysitis in a simian immunodeficiency virus-infected rhesusmacaque (Macacca mulatta).
J Med Primatol. 2017 Dec;46(6):364-367. doi: 10.1111/jmp.12289. Epub 2017 Jul 3. 2017.

Burwitz BJ, Wu HL, Abdulhaqq S, Shriver-Munsch C, Swanson T, Legasse AW, Hammond KB, Junell SL, Reed JS, Bimber BN, Greene JM, Webb GM, Northrup M, Laub W, Kievit P, MacAllister R, Axthelm MK, Ducore R, Lewis A, Colgin LMA, Hobbs T, Martin LD, Ferguson B, Thomas CR Jr, Panoskaltsis-Mortari A, Meyers G, Stanton JJ, Maziarz RT, Sacha JB
Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgusmacaques recapitulates diverse human clinical outcomes.
Nat Commun. 2017 Nov 10;8(1):1418. doi: 10.1038/s41467-017-01631-z. 2017.

Carryl H, Van Rompay KK, De Paris K, Burke MW
Hippocampal Neuronal Loss in Infant Macaques Orally Infected with Virulent SimianImmunodeficiency Virus (SIV).
Brain Sci. 2017 Apr 10;7(4). pii: brainsci7040040. doi: 10.3390/brainsci7040040. 2017.

Chang WL, Gonzalez DF, Kieu HT, Castillo LD, Messaoudi I, Shen X, Tomaras GD, Shacklett BL, Barry PA, Sparger EE
Changes in Circulating B Cell Subsets Associated with Aging and Acute SIVInfection in Rhesus Macaques.
PLoS One. 2017 Jan 17;12(1):e0170154. doi: 10.1371/journal.pone.0170154.eCollection 2017. 2017.

Daggett GJ Jr, Zhao C, Connor-Stroud F, Oviedo-Moreno P, Moon H, Cho MW, Moench T, Anderson DJ, Villinger F
Comparison of the vaginal environment in rhesus and cynomolgus macaques pre- and post-lactobacillus colonization.
J Med Primatol. 2017 Oct;46(5):232-238. doi: 10.1111/jmp.12264. Epub 2017 May 9. 2017.

Dross SE, Munson PV, Kim SE, Bratt DL, Tunggal HC, Gervassi AL, Fuller DH, Horton H
Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption.
J Immunol. 2017 Jan 15;198(2):757-766. doi: 10.4049/jimmunol.1600759. Epub 2016Dec 14. 2017.

Fan Q, Nelson CS, Bialas KM, Chiuppesi F, Amos J, Gurley TC, Marshall DJ, Eudailey J, Heimsath H, Himes J, Deshpande A, Walter MR, Wussow F, Diamond DJ, Barry PA, Moody MA, Kaur A, Permar SR
Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in aMonkey Model of Congenital CMV Transmission.
Clin Vaccine Immunol. 2017 May 5;24(5). pii: CVI.00510-16. doi:10.1128/CVI.00510-16. Print 2017 May. 2017.

Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z
A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV)evolution reveals a highly dynamic process within the host.
PLoS Pathog. 2017 May 25;13(5):e1006358. doi: 10.1371/journal.ppat.1006358.eCollection 2017 May. 2017.

Foreman TW, Mehra S, Lackner AA, Kaushal D
Translational Research in the Nonhuman Primate Model of Tuberculosis.
ILAR J. 2017 Dec 1;58(2):151-159. doi: 10.1093/ilar/ilx015. 2017.

Foreman TW, Veatch AV, LoBato DN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Lackner AA, Kousoulas KG, Khader SA, Kaushal D, Mehra S
Nonpathologic Infection of Macaques by an Attenuated Mycobacterial Vaccine Is NotReactivated in the Setting of HIV Co-Infection.
Am J Pathol. 2017 Dec;187(12):2811-2820. doi: 10.1016/j.ajpath.2017.08.014. Epub 2017 Sep 19. 2017.

Fruh K, Picker L
CD8+ T cell programming by cytomegalovirus vectors: applications in prophylactic and therapeutic vaccination.
Curr Opin Immunol. 2017 Aug;47:52-56. doi: 10.1016/j.coi.2017.06.010. Epub 2017Jul 19. 2017.

Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, Shichino S, Shiino T, Saito Y, Watanabe S, Sugimoto C, Kuroda MJ, Ato M, Nagai Y, Izumo S, Matsushima K, Miyazawa M, Ansari AA, Villinger F, Mori K
Simian Immunodeficiency Virus Targeting of CXCR3(+) CD4(+) T Cells in SecondaryLymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.
J Virol. 2017 Jun 9;91(13). pii: JVI.00439-17. doi: 10.1128/JVI.00439-17. Print2017 Jul 1. 2017.

Guo W, Pencina KM, O'Connell K, Montano M, Peng L, Westmoreland S, Glowacki J, Bhasin S
Administration of an activin receptor IIB ligand trap protects male juvenilerhesus macaques from simian immunodeficiency virus-associated bone loss.
Bone. 2017 Apr;97:209-215. doi: 10.1016/j.bone.2017.01.032. Epub 2017 Jan 26. 2017.

Hong JJ, Silveira ELDV, Amancha PK, Byrareddy SN, Gumber S, Chang KT, Ansari AA, Villinger F
Early initiation of antiretroviral treatment postSIV infection does not resolvelymphoid tissue activation.
AIDS. 2017 Aug 24;31(13):1819-1824. doi: 10.1097/QAD.0000000000001576. 2017.

Jaworski JP, Bryk P, Brower Z, Zheng B, Hessell AJ, Rosenberg AF, Wu TT, Sanz I, Keefer MC, Haigwood NL, Kobie JJ
Pre-existing neutralizing antibody mitigates B cell dysregulation and enhancesthe Env-specific antibody response in SHIV-infected rhesus macaques.
PLoS One. 2017 Feb 21;12(2):e0172524. doi: 10.1371/journal.pone.0172524.eCollection 2017. 2017.

Jensen K, Dela Pena-Ponce MG, Piatak M Jr, Shoemaker R, Oswald K, Jacobs WR Jr, Fennelly G, Lucero C, Mollan KR, Hudgens MG, Amedee A, Kozlowski PA, Estes JD, Lifson JD, Van Rompay KK, Larsen M, De Paris K
Balancing Trained Immunity with Persistent Immune Activation and the Risk ofSimian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.
Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: CVI.00360-16. doi:10.1128/CVI.00360-16. Print 2017 Jan. 2017.

Johnson AL, Van Rompay K, Reader JR
Pneumatosis intestinalis in an SIV-infected rhesus macaque (Macaca mulatta).
J Med Primatol. 2017 Dec;46(6):368-371. doi: 10.1111/jmp.12305. Epub 2017 Aug 15. 2017.

Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira ELV, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, Chen X, Amara RR, Hunter E, Bosinger SE, Spearman P, Crotty S, Villinger F, Derdeyn CA, Wrammert J, Pulendran B
Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like ReceptorLigands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5alpha Restrictive Macaques.
J Virol. 2017 Jan 31;91(4). pii: JVI.01844-16. doi: 10.1128/JVI.01844-16. Print2017 Feb 15. 2017.

Kirtane AR, Rothenberger MK, Frieberg A, Nephew K, Schultz-Darken N, Schmidt T, Reimann T, Haase AT, Panyam J
Evaluation of Vaginal Drug Levels and Safety of a Locally Administered GlycerolMonolaurate Cream in Rhesus Macaques.
J Pharm Sci. 2017 Jul;106(7):1821-1827. doi: 10.1016/j.xphs.2017.03.030. Epub2017 Apr 4. 2017.

Kulkarni V, Ruprecht RM
Mucosal IgA Responses: Damaged in Established HIV Infection-Yet, Effective Weaponagainst HIV Transmission.
Front Immunol. 2017 Nov 15;8:1581. doi: 10.3389/fimmu.2017.01581. eCollection2017. 2017.

Li H, Omange RW, Czarnecki C, Correia-Pinto JF, Crecente-Campo J, Richmond M, Li L, Schultz-Darken N, Alonso MJ, Whitney JB, Plummer FA, Luo M
Mauritian cynomolgus macaques with M3M4 MHC genotype control SIVmac251 infection.
J Med Primatol. 2017 Aug;46(4):137-143. doi: 10.1111/jmp.12300. 2017.

Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreno-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S 3rd, Lifson JD, Desrosiers RC, Watkins DI
Vaccine-induced immune responses against both Gag and Env improve control ofsimian immunodeficiency virus replication in rectally challenged rhesus macaques.
PLoS Pathog. 2017 Jul 21;13(7):e1006529. doi: 10.1371/journal.ppat.1006529.eCollection 2017 Jul. 2017.

Martins MA, Tully DC, Shin YC, Gonzalez-Nieto L, Weisgrau KL, Bean DJ, Gadgil R, Gutman MJ, Domingues A, Maxwell HS, Magnani DM, Ricciardi M, Pedreno-Lopez N, Bailey V, Cruz MA, Lima NS, Bonaldo MC, Altman JD, Rakasz E, Capuano S 3rd, Reimann KA, Piatak M Jr, Lifson JD, Desrosiers RC, Allen TM, Watkins DI
Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque.
AIDS Res Hum Retroviruses. 2017 Aug;33(8):843-858. doi: 10.1089/AID.2017.0046.Epub 2017 Jun 29. 2017.

McMichael AJ, Picker LJ
Unusual antigen presentation offers new insight into HIV vaccine design.
Curr Opin Immunol. 2017 Jun;46:75-81. doi: 10.1016/j.coi.2017.04.009. Epub 2017May 12. 2017.

Mendez-Lagares G, Lu D, Merriam D, Baker CA, Villinger F, Van Rompay KKA, McCune JM, Hartigan-O'Connor DJ
IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8(+) T CellResponses in Acute Simian Immunodeficiency Virus Infection.
AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S81-S92. doi: 10.1089/aid.2017.0160. 2017.

Merino KM, Allers C, Didier ES, Kuroda MJ
Role of Monocyte/Macrophages during HIV/SIV Infection in Adult and PediatricAcquired Immune Deficiency Syndrome.
Front Immunol. 2017 Dec 5;8:1693. doi: 10.3389/fimmu.2017.01693. eCollection2017. 2017.

Mylvaganam GH, Rios D, Abdelaal HM, Iyer S, Tharp G, Mavigner M, Hicks S, Chahroudi A, Ahmed R, Bosinger SE, Williams IR, Skinner PJ, Velu V, Amara RR
Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1976-1981. doi:10.1073/pnas.1621418114. Epub 2017 Feb 3. 2017.

Nixon CC, Mavigner M, Silvestri G, Garcia JV
In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies.
J Infect Dis. 2017 Mar 15;215(suppl_3):S142-S151. doi: 10.1093/infdis/jiw637. 2017.

Pace BT, Lackner AA, Porter E, Pahar B
The Role of Defensins in HIV Pathogenesis.
Mediators Inflamm. 2017;2017:5186904. doi: 10.1155/2017/5186904. Epub 2017 Aug 3. 2017.

Pahar B, Lala W, Kuebler D, Liu D
A significant productive in vivo infection of resting cells with simianimmunodeficiency virus in a macaque with AIDS.
J Med Primatol. 2017 Apr;46(2):59-62. doi: 10.1111/jmp.12252. Epub 2017 Feb 1. 2017.

Peterson CW, Benne C, Polacino P, Kaur J, McAllister CE, Filali-Mouhim A, Obenza W, Pecor TA, Huang ML, Baldessari A, Murnane RD, Woolfrey AE, Jerome KR, Hu SL, Klatt NR, DeRosa S, Sekaly RP, Kiem HP
Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation.
JCI Insight. 2017 Feb 23;2(4):e91230. doi: 10.1172/jci.insight.91230. 2017.

Pincus SH, Song K, Maresh GA, Frank A, Worthylake D, Chung HK, Polacino P, Hamer DH, Coyne CP, Rosenblum MG, Marks JW, Chen G, Weiss D, Ghetie V, Vitetta ES, Robinson JE, Hu SL
Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160.
J Virol. 2017 Jan 18;91(3). pii: JVI.01360-16. doi: 10.1128/JVI.01360-16. Print2017 Feb 1. 2017.

Plotnik D, Guo W, Cleveland B, von Haller P, Eng JK, Guttman M, Lee KK, Arthos J, Hu SL
Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with alpha4beta7.
J Virol. 2017 Oct 13;91(21). pii: JVI.01005-17. doi: 10.1128/JVI.01005-17. Print 2017 Nov 1. 2017.

Rahmberg AR, Rajakumar PA, Billingsley JM, Johnson RP
Dynamic Modulation of Expression of Lentiviral Restriction Factors in PrimaryCD4(+) T Cells following Simian Immunodeficiency Virus Infection.
J Virol. 2017 Mar 13;91(7). pii: JVI.02189-16. doi: 10.1128/JVI.02189-16. Print2017 Apr 1. 2017.

Richard J, Prevost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH, Kaufmann DE, Smith AB 3rd, Sodroski J, Sauter D, Kirchhoff F, Gee K, Neil SJ, Evans DT, Finzi A
BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-InfectedCells to Antibody-Dependent Cellular Cytotoxicity.
J Virol. 2017 May 12;91(11). pii: JVI.00219-17. doi: 10.1128/JVI.00219-17. Print 2017 Jun 1. 2017.

Ruprecht RM
Anti-HIV Passive Immunization: New Weapons in the Arsenal.
Trends Microbiol. 2017 Dec;25(12):954-956. doi: 10.1016/j.tim.2017.10.006. Epub2017 Oct 30. 2017.

Shang L, Duan L, Perkey KE, Wietgrefe S, Zupancic M, Smith AJ, Southern PJ, Johnson RP, Haase AT
Epithelium-innate immune cell axis in mucosal responses to SIV.
Mucosal Immunol. 2017 Mar;10(2):508-519. doi: 10.1038/mi.2016.62. Epub 2016 Jul20. 2017.

Sugimoto C, Merino KM, Hasegawa A, Wang X, Alvarez XA, Wakao H, Mori K, Kim WK, Veazey RS, Didier ES, Kuroda MJ
Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in PediatricSimian Immunodeficiency Virus-Infected Rhesus Macaques.
J Virol. 2017 Aug 10;91(17). pii: JVI.00379-17. doi: 10.1128/JVI.00379-17. Print 2017 Sep 1. 2017.

Sugimoto C, Merino KM, Hasegawa A, Wang X, Alvarez XA, Wakao H, Mori K, Kim WK, Veazey RS, Didier ES, Kuroda MJ
Correction for Sugimoto et al., 'Critical Role for Monocytes/Macrophages in RapidProgression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques'.
J Virol. 2017 Oct 27;91(22). pii: 91/22/e01346-17. doi: 10.1128/JVI.01346-17.Print 2017 Nov 15. 2017.

Van Rompay KKA
Tackling HIV and AIDS: contributions by non-human primate models.
Lab Anim (NY). 2017 May 22;46(6):259-270. doi: 10.1038/laban.1279. 2017.

Veazey RS, Lackner AA
Nonhuman Primate Models and Understanding the Pathogenesis of HIV Infection andAIDS.
ILAR J. 2017 Dec 1;58(2):160-171. doi: 10.1093/ilar/ilx032. 2017.

Veazey RS, Ling B
Short Communication: Comparative Susceptibility of Rhesus Macaques of Indian and Chinese Origin to Vaginal Simian-Human Immunodeficiency Virus Transmission as Models for HIV Prevention Research.
AIDS Res Hum Retroviruses. 2017 Dec;33(12):1199-1201. doi: 10.1089/AID.2017.0173.Epub 2017 Nov 7. 2017.

Zevin AS, Hensley-McBain T, Miller C, Smith E, Langevin S, Klatt NR
Antibiotic treatment disrupts bacterial communities in the colon and rectum ofsimian immunodeficiency virus-infected macaques.
FEMS Microbiol Lett. 2017 Dec 15;364(23). pii: 4569069. doi:10.1093/femsle/fnx228. 2017.

Zevin AS, Moats C, May D, Wangari S, Miller C, Ahrens J, Iwayama N, Brown M, Bratt D, Klatt NR, Smedley J
Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques.
J Vis Exp. 2017 May 2;(123). doi: 10.3791/55617. 2017.

Zhao C, Gunawardana M, Villinger F, Baum MM, Remedios-Chan M, Moench TR, Zeitlin L, Whaley KJ, Bohorov O, Smith TJ, Anderson DJ, Moss JA
Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model.
Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: AAC.02465-16. doi:10.1128/AAC.02465-16. Print 2017 Jul. 2017.

2016

Arias JF, Colomer-Lluch M, von Bredow B, Greene JM, MacDonald J, O'Connor DH, Serra-Moreno R, Evans DT
Tetherin Antagonism by HIV-1 Group M Nef Proteins.
J Virol. 2016 Nov 14;90(23):10701-10714. doi: 10.1128/JVI.01465-16. Print 2016Dec 1. 2016.

Arrode-Bruses G, Goode D, Kleinbeck K, Wilk J, Frank I, Byrareddy S, Arthos J, Grasperge B, Blanchard J, Zydowsky T, Gettie A, Martinelli E
A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin alpha4beta7and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
PLoS Pathog. 2016 Jun 27;12(6):e1005720. doi: 10.1371/journal.ppat.1005720.eCollection 2016 Jun. 2016.

Bailey AL, Lauck M, Ghai RR, Nelson CW, Heimbruch K, Hughes AL, Goldberg TL, Kuhn JH, Jasinska AJ, Freimer NB, Apetrei C, O'Connor DH
Arteriviruses, Pegiviruses, and Lentiviruses Are Common among Wild AfricanMonkeys.
J Virol. 2016 Jul 11;90(15):6724-6737. doi: 10.1128/JVI.00573-16. Print 2016 Aug 1. 2016.

Byrareddy SN, Arthos J, Cicala C, Villinger F, Ortiz KT, Little D, Sidell N, Kane MA, Yu J, Jones JW, Santangelo PJ, Zurla C, McKinnon LR, Arnold KB, Woody CE, Walter L, Roos C, Noll A, Van Ryk D, Jelicic K, Cimbro R, Gumber S, Reid MD, Adsay V, Amancha PK, Mayne AE, Parslow TG, Fauci AS, Ansari AA
Sustained virologic control in SIV+ macaques after antiretroviral and alpha4beta7antibody therapy.
Science. 2016 Oct 14;354(6309):197-202. doi: 10.1126/science.aag1276. 2016.

Calascibetta F, Micci L, Carnathan D, Lawson B, Vanderford TH, Bosinger SE, Easley K, Chahroudi A, Mackel J, Keele BF, Long S, Lifson J, Paiardini M, Silvestri G
Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys:Implications for AIDS Pathogenesis.
J Virol. 2016 Jul 27;90(16):7541-7551. doi: 10.1128/JVI.00598-16. Print 2016 Aug 15. 2016.

Cartwright EK, Palesch D, Mavigner M, Paiardini M, Chahroudi A, Silvestri G
Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasisin Simian Immunodeficiency Virus-Infected Macaques.
J Virol. 2016 Jul 11;90(15):6699-6708. doi: 10.1128/JVI.00492-16. Print 2016 Aug 1. 2016.

Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, Lifson JD, Derdeyn CA, Silvestri G
CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-InfectedMacaques Treated with Short-Term Antiretroviral Therapy.
Immunity. 2016 Sep 20;45(3):656-668. doi: 10.1016/j.immuni.2016.08.018. 2016.

Chamcha V, Kannanganat S, Gangadhara S, Nabi R, Kozlowski PA, Montefiori DC, LaBranche CC, Wrammert J, Keele BF, Balachandran H, Sahu S, Lifton M, Santra S, Basu R, Moss B, Robinson HL, Amara RR
Strong, but Age-Dependent, Protection Elicited by a DeoxyribonucleicAcid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine.
Open Forum Infect Dis. 2016 Feb 11;3(1):ofw034. doi: 10.1093/ofid/ofw034.eCollection 2016 Jan. 2016.

Del Prete GQ, Smedley J, Macallister R, Jones GS, Li B, Hattersley J, Zheng J, Piatak M Jr, Keele BF, Hesselgesser J, Geleziunas R, Lifson JD
Short Communication: Comparative Evaluation of Coformulated InjectableCombination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques.
AIDS Res Hum Retroviruses. 2016 Feb;32(2):163-8. doi: 10.1089/AID.2015.0130. Epub2015 Sep 9. 2016.

Ericsen AJ, Lauck M, Mohns MS, DiNapoli SR, Mutschler JP, Greene JM, Weinfurter JT, Lehrer-Brey G, Prall TM, Gieger SM, Buechler CR, Crosno KA, Peterson EJ, Reynolds MR, Wiseman RW, Burwitz BJ, Estes JD, Sacha JB, Friedrich TC, Brenchley JM, O'Connor DH
Microbial Translocation and Inflammation Occur in Hyperacute ImmunodeficiencyVirus Infection and Compromise Host Control of Virus Replication.
PLoS Pathog. 2016 Dec 7;12(12):e1006048. doi: 10.1371/journal.ppat.1006048.eCollection 2016 Dec. 2016.

Evans TI, Li H, Schafer JL, Klatt NR, Hao XP, Traslavina RP, Estes JD, Brenchley JM, Reeves RK
SIV-induced Translocation of Bacterial Products in the Liver Mobilizes MyeloidDendritic and Natural Killer Cells Associated With Liver Damage.
J Infect Dis. 2016 Feb 1;213(3):361-9. doi: 10.1093/infdis/jiv404. Epub 2015 Aug 3. 2016.

Filipowicz AR, McGary CM, Holder GE, Lindgren AA, Johnson EM, Sugimoto C, Kuroda MJ, Kim WK
Proliferation of Perivascular Macrophages Contributes to the Development ofEncephalitic Lesions in HIV-Infected Humans and in SIV-Infected Macaques.
Sci Rep. 2016 Sep 9;6:32900. doi: 10.1038/srep32900. 2016.

Ford SM Jr, Simon L, Vande Stouwe C, Allerton T, Mercante DE, Byerley LO, Dufour JP, Bagby GJ, Nelson S, Molina PE
Chronic binge alcohol administration impairs glucose-insulin dynamics anddecreases adiponectin in asymptomatic simian immunodeficiency virus-infected macaques.
Am J Physiol Regul Integr Comp Physiol. 2016 Nov 1;311(5):R888-R897. doi:10.1152/ajpregu.00142.2016. Epub 2016 Sep 7. 2016.

Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucsan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosisin a macaque model of HIV coinfection.
Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi:10.1073/pnas.1611987113. Epub 2016 Sep 6. 2016.

Gellerup DD, Balgeman AJ, Nelson CW, Ericsen AJ, Scarlotta M, Hughes AL, O'Connor SL
Conditional Immune Escape during Chronic Simian Immunodeficiency Virus Infection.
J Virol. 2015 Oct 21;90(1):545-52. doi: 10.1128/JVI.02587-15. Print 2016 Jan 1. 2016.

Glavan TW, Gaulke CA, Santos Rocha C, Sankaran-Walters S, Hirao LA, Raffatellu M, Jiang G, Baumler AJ, Goulart LR, Dandekar S
Gut immune dysfunction through impaired innate pattern recognition receptorexpression and gut microbiota dysbiosis in chronic SIV infection.
Mucosal Immunol. 2016 May;9(3):677-88. doi: 10.1038/mi.2015.92. Epub 2015 Sep 16. 2016.

Guerra-Perez N, Aravantinou M, Veglia F, Goode D, Truong R, Derby N, Blanchard J, Grasperge B, Gettie A, Robbiani M, Martinelli E
Rectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context ofSIVDeltanef Vaccination.
PLoS One. 2016 Feb 17;11(2):e0149491. doi: 10.1371/journal.pone.0149491.eCollection 2016. 2016.

Hansen SG, Wu HL, Burwitz BJ, Hughes CM, Hammond KB, Ventura AB, Reed JS, Gilbride RM, Ainslie E, Morrow DW, Ford JC, Selseth AN, Pathak R, Malouli D, Legasse AW, Axthelm MK, Nelson JA, Gillespie GM, Walters LC, Brackenridge S, Sharpe HR, Lopez CA, Fruh K, Korber BT, McMichael AJ, Gnanakaran S, Sacha JB, Picker LJ
Broadly targeted CD8(+) T cell responses restricted by major histocompatibilitycomplex E.
Science. 2016 Feb 12;351(6274):714-20. doi: 10.1126/science.aac9475. Epub 2016Jan 21. 2016.

Hensley-McBain T, Zevin AS, Manuzak J, Smith E, Gile J, Miller C, Agricola B, Katze M, Reeves RK, Kraft CS, Langevin S, Klatt NR
Effects of Fecal Microbial Transplantation on Microbiome and Immunity in SimianImmunodeficiency Virus-Infected Macaques.
J Virol. 2016 Apr 29;90(10):4981-4989. doi: 10.1128/JVI.00099-16. Print 2016 May 15. 2016.

Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, Reed J, Sutton WF, Hammond KB, Cheever TA, Barnette PT, Legasse AW, Planer S, Stanton JJ, Pegu A, Chen X, Wang K, Siess D, Burke D, Park BS, Axthelm MK, Lewis A, Hirsch VM, Graham BS, Mascola JR, Sacha JB, Haigwood NL
Early short-term treatment with neutralizing human monoclonal antibodies haltsSHIV infection in infant macaques.
Nat Med. 2016 Apr;22(4):362-8. doi: 10.1038/nm.4063. Epub 2016 Mar 21. 2016.

Hodara VL, Parodi LM, Keckler MS, Giavedoni LD
Increases in NKG2C Expression on T Cells and Higher Levels of Circulating CD8(+) B Cells Are Associated with Sterilizing Immunity Provided by a Live Attenuated SIV Vaccine.
AIDS Res Hum Retroviruses. 2016 Oct/Nov;32(10-11):1125-1134. doi:10.1089/aid.2015.0300. Epub 2016 Mar 17. 2016.

Iyer SS, Gangadhara S, Victor B, Shen X, Chen X, Nabi R, Kasturi SP, Sabula MJ, Labranche CC, Reddy PB, Tomaras GD, Montefiori DC, Moss B, Spearman P, Pulendran B, Kozlowski PA, Amara RR
Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV)Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques.
J Virol. 2016 Sep 12;90(19):8842-54. doi: 10.1128/JVI.01163-16. Print 2016 Oct 1. 2016.

Jean-Pierre N, Barnable P, Kizima L, Rodriguez A, Seidor S, Cooney ML, Clark MR, Doncel GF, Robbiani M, Zydowsky TM, Teleshova N, Fernandez-Romero JA
Multipurpose Prevention Approaches with Antiretroviral-Based Formulations.
Antimicrob Agents Chemother. 2015 Nov 23;60(2):1141-4. doi: 10.1128/AAC.02468-15.Print 2016 Feb. 2016.

Jensen K, Nabi R, Van Rompay KKA, Robichaux S, Lifson JD, Piatak M Jr, Jacobs WR Jr, Fennelly G, Canfield D, Mollan KR, Hudgens MG, Larsen MH, Amedee AM, Kozlowski PA, De Paris K
Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated withReduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques.
J Virol. 2016 Jul 27;90(16):7285-7302. doi: 10.1128/JVI.00481-16. Print 2016 Aug 15. 2016.

Johnston C, Harrington R, Jain R, Schiffer J, Kiem HP, Woolfrey A
Safety and Efficacy of Combination Antiretroviral Therapy in HumanImmunodeficiency Virus-Infected Adults Undergoing Autologous or Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies.
Biol Blood Marrow Transplant. 2016 Jan;22(1):149-56. doi:10.1016/j.bbmt.2015.08.006. Epub 2015 Aug 8. 2016.

Kannanganat S, Wyatt LS, Gangadhara S, Chamcha V, Chea LS, Kozlowski PA, LaBranche CC, Chennareddi L, Lawson B, Reddy PB, Styles TM, Vanderford TH, Montefiori DC, Moss B, Robinson HL, Amara RR
High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and DiminishModified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5alpha-Restrictive Macaques.
J Immunol. 2016 Nov 1;197(9):3586-3596. doi: 10.4049/jimmunol.1600629. Epub 2016 Sep 28. 2016.

Keating SM, Heitman JW, Wu S, Deng X, Stacey AR, Zahn RC, de la Rosa M, Finstad SL, Lifson JD, Piatak M Jr, Gauduin MC, Kessler BM, Ternette N, Carville A, Johnson RP, Desrosiers RC, Letvin NL, Borrow P, Norris PJ, Schmitz JE
Magnitude and Quality of Cytokine and Chemokine Storm during Acute InfectionDistinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates.
J Virol. 2016 Oct 28;90(22):10339-10350. doi: 10.1128/JVI.01061-16. Print 2016Nov 15. 2016.

Krebs KC, Tian M, Asmal M, Ling B, Nelson K, Henry K, Gibson R, Li Y, Han W, Shattock RJ, Veazey RS, Letvin N, Arts EJ, Gao Y
Infection of rhesus macaques with a pool of simian immunodeficiency virus withthe envelope genes from acute HIV-1 infections.
AIDS Res Ther. 2016 Nov 25;13(1):41. doi: 10.1186/s12981-016-0125-8. 2016.

Kumar N, Chahroudi A, Silvestri G
Animal models to achieve an HIV cure.
Curr Opin HIV AIDS. 2016 Jul;11(4):432-41. doi: 10.1097/COH.0000000000000290. 2016.

Kumar V, Torben W, Kenway CS, Schiro FR, Mohan M
Longitudinal Examination of the Intestinal Lamina Propria Cellular Compartment ofSimian Immunodeficiency Virus-Infected Rhesus Macaques Provides Broader and Deeper Insights into the Link between Aberrant MicroRNA Expression and Persistent Immune Activation.
J Virol. 2016 Apr 29;90(10):5003-5019. doi: 10.1128/JVI.00189-16. Print 2016 May 15. 2016.

Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter M, Yuan S, Yan J, Ginsberg A, Sylvester A, Pahar B, Carnathan D, Kathuria N, Khan AS, Montefiori D, Sardesai NY, Betts MR, Mestecky J, Marx P, Weiner DB
Chemokine-adjuvanted electroporated DNA vaccine induces substantial protectionfrom simian immunodeficiency virus vaginal challenge.
Mucosal Immunol. 2016 Jan;9(1):13-23. doi: 10.1038/mi.2015.31. Epub 2015 May 6. 2016.

Lee M, Kim WK, Kuroda MJ, Pal R, Chung HK
Development of real-time PCR for quantitation of simian immunodeficiency virus2-LTR circles.
J Med Primatol. 2016 Oct;45(5):215-21. doi: 10.1111/jmp.12244. Epub 2016 Sep 20. 2016.

Li S, Folkvord JM, Rakasz EG, Abdelaal HM, Wagstaff RK, Kovacs KJ, Kim HO, Sawahata R, MaWhinney S, Masopust D, Connick E, Skinner PJ
Simian Immunodeficiency Virus-Producing Cells in Follicles Are PartiallySuppressed by CD8+ Cells In Vivo.
J Virol. 2016 Nov 28;90(24):11168-11180. doi: 10.1128/JVI.01332-16. Print 2016Dec 15. 2016.

Ma ZM, Dutra J, Fritts L, Miller CJ
Lymphatic Dissemination of Simian Immunodeficiency Virus after PenileInoculation.
J Virol. 2016 Mar 28;90(8):4093-4104. doi: 10.1128/JVI.02947-15. Print 2016 Apr. 2016.

Martinez-Navio JM, Fuchs SP, Pedreno-Lopez S, Rakasz EG, Gao G, Desrosiers RC
Host Anti-antibody Responses Following Adeno-associated Virus-mediated Deliveryof Antibodies Against HIV and SIV in Rhesus Monkeys.
Mol Ther. 2016 Feb;24(1):76-86. doi: 10.1038/mt.2015.191. Epub 2015 Oct 7. 2016.

Mavigner M, Lee ST, Habib J, Robinson C, Silvestri G, O'Doherty U, Chahroudi A
Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
J Virus Erad. 2016 Oct 5;2(4):219-226. 2016.

Moldt B, Le KM, Carnathan DG, Whitney JB, Schultz N, Lewis MG, Borducchi EN, Smith KM, Mackel JJ, Sweat SL, Hodges AP, Godzik A, Parren PW, Silvestri G, Barouch DH, Burton DR
Neutralizing antibody affords comparable protection against vaginal and rectalsimian/human immunodeficiency virus challenge in macaques.
AIDS. 2016 Jun 19;30(10):1543-51. doi: 10.1097/QAD.0000000000001102. 2016.

Ofotokun I, Titanji K, Vunnava A, Roser-Page S, Vikulina T, Villinger F, Rogers K, Sheth AN, Lahiri CD, Lennox JL, Weitzmann MN
Antiretroviral therapy induces a rapid increase in bone resorption that ispositively associated with the magnitude of immune reconstitution in HIV infection.
AIDS. 2016 Jan 28;30(3):405-14. doi: 10.1097/QAD.0000000000000918. 2016.

Ortiz AM, Carnathan DG, Yu J, Sheehan KM, Kim P, Reynaldi A, Vanderford TH, Klatt NR, Brenchley JM, Davenport MP, Silvestri G
Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in ChronicallySIV-Infected Sooty Mangabeys.
PLoS One. 2016 May 26;11(5):e0156352. doi: 10.1371/journal.pone.0156352.eCollection 2016. 2016.

Ortiz AM, Klase ZA, DiNapoli SR, Vujkovic-Cvijin I, Carmack K, Perkins MR, Calantone N, Vinton CL, Riddick NE, Gallagher J, Klatt NR, McCune JM, Estes JD, Paiardini M, Brenchley JM
IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation,and microbiome in ARV-treated, SIV-infected macaques.
Mucosal Immunol. 2016 Mar;9(2):458-67. doi: 10.1038/mi.2015.75. Epub 2015 Aug 19. 2016.

Pahar B, Kenway-Lynch CS, Marx P, Srivastav SK, LaBranche C, Montefiori DC, Das A
Breadth and magnitude of antigen-specific antibody responses in the control ofplasma viremia in simian immunodeficiency virus infected macaques.
Virol J. 2016 Dec 1;13(1):200. doi: 10.1186/s12985-016-0652-x. 2016.

Panigrahi S, Freeman ML, Funderburg NT, Mudd JC, Younes SA, Sieg SF, Zidar DA, Paiardini M, Villinger F, Calabrese LH, Ransohoff RM, Jain MK, Lederman MM
SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression ofKruppel-like Factor 2 and Endothelial Dysfunction.
J Infect Dis. 2016 May 1;213(9):1419-27. doi: 10.1093/infdis/jiv749. Epub 2015Dec 15. 2016.

Peterson CW, Haworth KG, Burke BP, Polacino P, Norman KK, Adair JE, Hu SL, Bartlett JS, Symonds GP, Kiem HP
Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivoselection after SHIV infection in a nonhuman primate model of AIDS.
Mol Ther Methods Clin Dev. 2016 Feb 24;3:16007. doi: 10.1038/mtm.2016.7.eCollection 2016. 2016.

Peterson CW, Wang J, Norman KK, Norgaard ZK, Humbert O, Tse CK, Yan JJ, Trimble RG, Shivak DA, Rebar EJ, Gregory PD, Holmes MC, Kiem HP
Long-term multilineage engraftment of autologous genome-edited hematopoietic stemcells in nonhuman primates.
Blood. 2016 May 19;127(20):2416-26. doi: 10.1182/blood-2015-09-672337. Epub 2016 Mar 15. 2016.

Ploquin MJ, Silvestri G, Muller-Trutwin M
Immune activation in HIV infection: what can the natural hosts of simianimmunodeficiency virus teach us?
Curr Opin HIV AIDS. 2016 Mar;11(2):201-8. doi: 10.1097/COH.0000000000000238. 2016.

Simon L, Song K, Vande Stouwe C, Hollenbach A, Amedee A, Mohan M, Winsauer P, Molina P
Delta9-Tetrahydrocannabinol (Delta9-THC) Promotes Neuroimmune-Modulatory MicroRNAProfile in Striatum of Simian Immunodeficiency Virus (SIV)-Infected Macaques.
J Neuroimmune Pharmacol. 2016 Mar;11(1):192-213. doi: 10.1007/s11481-015-9645-6. Epub 2015 Nov 25. 2016.

Smith SA, Kilgore KM, Kasturi SP, Pulendran B, Hunter E, Amara RR, Derdeyn CA
Signatures in Simian Immunodeficiency Virus SIVsmE660 Envelope gp120 AreAssociated with Mucosal Transmission but Not Vaccination Breakthrough in Rhesus Macaques.
J Virol. 2015 Dec 16;90(4):1880-7. doi: 10.1128/JVI.02711-15. Print 2016 Feb 15. 2016.

Stieh DJ, Matias E, Xu H, Fought AJ, Blanchard JL, Marx PA, Veazey RS, Hope TJ
Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission ofSIV in Macaques.
Cell Host Microbe. 2016 Apr 13;19(4):529-40. doi: 10.1016/j.chom.2016.03.005. 2016.

Sutton MS, Burns CM, Weiler AM, Balgeman AJ, Braasch A, Lehrer-Brey G, Friedrich TC, O'Connor SL
Vaccination with Live Attenuated Simian Immunodeficiency Virus (SIV) Protectsfrom Mucosal, but Not Necessarily Intravenous, Challenge with a Minimally Heterologous SIV.
J Virol. 2016 May 27;90(12):5541-5548. doi: 10.1128/JVI.00192-16. Print 2016 Jun 15. 2016.

Swanstrom AE, Haggarty B, Jordan APO, Romano J, Leslie GJ, Aye PP, Marx PA, Lackner AA, Del Prete GQ, Robinson JE, Betts MR, Montefiori DC, LaBranche CC, Hoxie JA
Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic SimianImmunodeficiency Virus.
J Virol. 2016 Apr 29;90(10):4966-4980. doi: 10.1128/JVI.02851-15. Print 2016 May 15. 2016.

Townsley S, Li Y, Kozyrev Y, Cleveland B, Hu SL
Conserved Role of an N-Linked Glycan on the Surface Antigen of HumanImmunodeficiency Virus Type 1 Modulating Virus Sensitivity to Broadly Neutralizing Antibodies against the Receptor and Coreceptor Binding Sites.
J Virol. 2015 Oct 28;90(2):829-41. doi: 10.1128/JVI.02321-15. Print 2016 Jan 15. 2016.

Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, Ackerman ME, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, Pegu P, Montefiori DC, Foulds K, Quinn DS, Donaldson M, Liang F, Lore K, Roederer M, Koup RA, McDermott A, Ma ZM, Miller CJ, Phan TB, Forthal DN, Blackburn M, Caccuri F, Bissa M, Ferrari G, Kalyanaraman V, Ferrari MG, Thompson D, Robert-Guroff M, Ratto-Kim S, Kim JH, Michael NL, Phogat S, Barnett SW, Tartaglia J, Venzon D, Stablein DM, Alter G, Sekaly RP, Franchini G
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251acquisition.
Nat Med. 2016 Jul;22(7):762-70. doi: 10.1038/nm.4105. Epub 2016 May 30. 2016.

Veazey RS, Chatterji U, Bobardt M, Russell-Lodrigue KE, Li J, Wang X, Gallay PA
C5A Protects Macaques from Vaginal Simian-Human Immunodeficiency Virus Challenge.
Antimicrob Agents Chemother. 2015 Nov 9;60(1):693-8. doi: 10.1128/AAC.01925-15.Print 2016 Jan. 2016.

Veazey RS, Pilch-Cooper HA, Hope TJ, Alter G, Carias AM, Sips M, Wang X, Rodriguez B, Sieg SF, Reich A, Wilkinson P, Cameron MJ, Lederman MM
Prevention of SHIV transmission by topical IFN-beta treatment.
Mucosal Immunol. 2016 Nov;9(6):1528-1536. doi: 10.1038/mi.2015.146. Epub 2016 Feb3. 2016.

Velu V, Mylvaganam GH, Gangadhara S, Hong JJ, Iyer SS, Gumber S, Ibegbu CC, Villinger F, Amara RR
Induction of Th1-Biased T Follicular Helper (Tfh) Cells in Lymphoid Tissuesduring Chronic Simian Immunodeficiency Virus Infection Defines Functionally Distinct Germinal Center Tfh Cells.
J Immunol. 2016 Sep 1;197(5):1832-42. doi: 10.4049/jimmunol.1600143. Epub 2016Aug 1. 2016.

Villegas G, Calenda G, Ugaonkar S, Zhang S, Kizima L, Mizenina O, Gettie A, Blanchard J, Cooney ML, Robbiani M, Fernandez-Romero JA, Zydowsky TM, Teleshova N
A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque GenitalMucosa against SHIV-RT Infection Ex Vivo.
PLoS One. 2016 Jul 18;11(7):e0159332. doi: 10.1371/journal.pone.0159332.eCollection 2016. 2016.

von Bredow B, Arias JF, Heyer LN, Moldt B, Le K, Robinson JE, Zolla-Pazner S, Burton DR, Evans DT
Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and VirusNeutralization by HIV-1 Env-Specific Monoclonal Antibodies.
J Virol. 2016 Jun 10;90(13):6127-6139. doi: 10.1128/JVI.00347-16. Print 2016 Jul 1. 2016.

Weiler AM, Das A, Akinyosoye O, Cui S, O'Connor SL, Scheef EA, Reed JS, Panganiban AT, Sacha JB, Rakasz EG, Friedrich TC, Maness NJ
Acute Viral Escape Selectively Impairs Nef-Mediated Major HistocompatibilityComplex Class I Downmodulation and Increases Susceptibility to Antiviral T Cells.
J Virol. 2015 Dec 4;90(4):2119-26. doi: 10.1128/JVI.01975-15. Print 2016 Feb 15. 2016.

Xu H, Wang X, Malam N, Aye PP, Alvarez X, Lackner AA, Veazey RS
Persistent Simian Immunodeficiency Virus Infection Drives Differentiation,Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells.
J Virol. 2015 Nov 25;90(3):1578-87. doi: 10.1128/JVI.02471-15. Print 2016 Feb 1. 2016.

2015

Adnan S, Colantonio AD, Yu Y, Gillis J, Wong FE, Becker EA, Piatak M Jr, Reeves RK, Lifson JD, O'Connor SL, Johnson RP
CD8 T cell response maturation defined by anentropic specificity and repertoiredepth correlates with SIVDeltanef-induced protection.
PLoS Pathog. 2015 Feb 17;11(2):e1004633. doi: 10.1371/journal.ppat.1004633.eCollection 2015 Feb. 2015.

Allen SA, Carias AM, Anderson MR, Okocha EA, Benning L, McRaven MD, Kelley ZL, Lurain J, Veazey RS, Hope TJ
Characterization of the Influence of Semen-Derived Enhancer of Virus Infection onthe Interaction of HIV-1 with Female Reproductive Tract Tissues.
J Virol. 2015 May;89(10):5569-80. doi: 10.1128/JVI.00309-15. Epub 2015 Mar 4. 2015.

Amancha PK, Hong JJ, Ansari AA, Villinger F
Up-regulation of Tim-3 on T cells during acute simian immunodeficiency virusinfection and on antigen specific responders.
AIDS. 2015 Mar 13;29(5):531-6. doi: 10.1097/QAD.0000000000000589. 2015.

Andrews CD, Yueh YL, Spreen WR, St Bernard L, Boente-Carrera M, Rodriguez K, Gettie A, Russell-Lodrigue K, Blanchard J, Ford S, Mohri H, Cheng-Mayer C, Hong Z, Ho DD, Markowitz M
A long-acting integrase inhibitor protects female macaques from repeatedhigh-dose intravaginal SHIV challenge.
Sci Transl Med. 2015 Jan 14;7(270):270ra4. doi: 10.1126/scitranslmed.3010298. 2015.

Assaf BT, Knight HL, Miller AD
rhesus cytomegalovirus (macacine herpesvirus 3)-associated facial neuritis insimian immunodeficiency virus-infected rhesus macaques (Macaca mulatta).
Vet Pathol. 2015 Jan;52(1):217-23. doi: 10.1177/0300985814529313. Epub 2014 Mar31. 2015.

Baker CA, Swainson L, Lin DL, Wong S, Hartigan-O'Connor DJ, Lifson JD, Tarantal AF, McCune JM
Exposure to SIV in utero results in reduced viral loads and alteredresponsiveness to postnatal challenge.
Sci Transl Med. 2015 Aug 12;7(300):300ra125. doi: 10.1126/scitranslmed.aac5547. 2015.

Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP Jr, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH
Neutralization properties of simian immunodeficiency viruses infectingchimpanzees and gorillas.
MBio. 2015 Apr 21;6(2). pii: mBio.00296-15. doi: 10.1128/mBio.00296-15. 2015.

Barnable P, Calenda G, Bonnaire T, Menon R, Levendosky K, Gettie A, Blanchard J, Cooney ML, Fernandez-Romero JA, Zydowsky TM, Teleshova N
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiencyvirus reverse transcriptase infection in a macaque vaginal explant model.
Antimicrob Agents Chemother. 2015 Jul;59(7):3829-37. doi: 10.1128/AAC.00073-15.Epub 2015 Apr 13. 2015.

Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, Seaman MS, Lavine CL, Perry JR, Li W, Colantonio AD, Lewis MG, Chen B, Wenschuh H, Reimer U, Piatak M, Lifson JD, Handley SA, Virgin HW, Koutsoukos M, Lorin C, Voss G, Weijtens M, Pau MG, Schuitemaker H
Protective efficacy of adenovirus/protein vaccines against SIV challenges inrhesus monkeys.
Science. 2015 Jul 17;349(6245):320-4. doi: 10.1126/science.aab3886. Epub 2015 Jul2. 2015.

Bimber BN, Evans DT
The killer-cell immunoglobulin-like receptors of macaques.
Immunol Rev. 2015 Sep;267(1):246-58. doi: 10.1111/imr.12329. 2015.

Blackburn MJ, Zhong-Min M, Caccuri F, McKinnon K, Schifanella L, Guan Y, Gorini G, Venzon D, Fenizia C, Binello N, Gordon SN, Miller CJ, Franchini G, Vaccari M
Regulatory and Helper Follicular T Cells and Antibody Avidity to SimianImmunodeficiency Virus Glycoprotein 120.
J Immunol. 2015 Oct 1;195(7):3227-36. doi: 10.4049/jimmunol.1402699. Epub 2015Aug 21. 2015.

Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, O'Connor DH, LaBranche CC, Montefiori DC, Marsh M, Li Y, Piatak M Jr, Lifson JD, Keele BF, Fultz PN, Lackner AA, Hoxie JA
Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses inMacaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.
J Virol. 2015 Oct;89(20):10156-75. doi: 10.1128/JVI.01134-15. Epub 2015 Jul 29. 2015.

Bricault CA, Kovacs JM, Nkolola JP, Yusim K, Giorgi EE, Shields JL, Perry J, Lavine CL, Cheung A, Ellingson-Strouss K, Rademeyer C, Gray GE, Williamson C, Stamatatos L, Seaman MS, Korber BT, Chen B, Barouch DH
A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude ofneutralizing antibodies than any individual component.
J Virol. 2015 Mar;89(5):2507-19. doi: 10.1128/JVI.03331-14. Epub 2014 Dec 24. 2015.

Burtner CR, Chandrasekaran D, Santos EB, Beard BC, Adair JE, Hamlin DK, Wilbur DS, Sandmaier BM, Kiem HP
(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based NonmyeloablativeConditioning for Stem Cell Gene Therapy.
Hum Gene Ther. 2015 Jun;26(6):399-406. doi: 10.1089/hum.2015.021. 2015.

Burton SL, Kilgore KM, Smith SA, Reddy S, Hunter E, Robinson HL, Silvestri G, Amara RR, Derdeyn CA
Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinatedrhesus macaques despite potent autologous neutralizing antibody responses.
Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10780-5. doi:10.1073/pnas.1509731112. Epub 2015 Aug 10. 2015.

Byrareddy SN, Little D, Mayne AE, Villinger F, Ansari AA
Phenotypic and Functional Characterization of Monoclonal Antibodies withSpecificity for Rhesus Macaque CD200, CD200R and Mincle.
PLoS One. 2015 Oct 15;10(10):e0140689. doi: 10.1371/journal.pone.0140689.eCollection 2015. 2015.

Cai Y, Sugimoto C, Arainga M, Midkiff CC, Liu DX, Alvarez X, Lackner AA, Kim WK, Didier ES, Kuroda MJ
Preferential Destruction of Interstitial Macrophages over Alveolar Macrophages asa Cause of Pulmonary Disease in Simian Immunodeficiency Virus-Infected Rhesus Macaques.
J Immunol. 2015 Nov 15;195(10):4884-91. doi: 10.4049/jimmunol.1501194. Epub 2015 Oct 2. 2015.

Carnathan DG, Wetzel KS, Yu J, Lee ST, Johnson BA, Paiardini M, Yan J, Morrow MP, Sardesai NY, Weiner DB, Ertl HC, Silvestri G
Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition inSIVGag/Tat-vaccinated rhesus macaques.
Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):518-23. doi:10.1073/pnas.1407466112. Epub 2014 Dec 30. 2015.

Carryl H, Swang M, Lawrence J, Curtis K, Kamboj H, Van Rompay KK, De Paris K, Burke MW
Of mice and monkeys: can animal models be utilized to study neurologicalconsequences of pediatric HIV-1 infection?
ACS Chem Neurosci. 2015 Aug 19;6(8):1276-89. doi: 10.1021/acschemneuro.5b00044.Epub 2015 Jun 19. 2015.

Chandra LC, Kumar V, Torben W, Vande Stouwe C, Winsauer P, Amedee A, Molina PE, Mohan M
Chronic administration of Delta9-tetrahydrocannabinol induces intestinalanti-inflammatory microRNA expression during acute simian immunodeficiency virus infection of rhesus macaques.
J Virol. 2015 Jan 15;89(2):1168-81. doi: 10.1128/JVI.01754-14. Epub 2014 Nov 5. 2015.

Chang HW, Tartaglia LJ, Whitney JB, Lim SY, Sanisetty S, Lavine CL, Seaman MS, Rademeyer C, Williamson C, Ellingson-Strouss K, Stamatatos L, Kublin J, Barouch DH
Generation and evaluation of clade C simian-human immunodeficiency viruschallenge stocks.
J Virol. 2015 Feb;89(4):1965-74. doi: 10.1128/JVI.03279-14. Epub 2014 Dec 3. 2015.

Chowdhury A, Del Rio Estrada PM, Tharp GK, Trible RP, Amara RR, Chahroudi A, Reyes-Teran G, Bosinger SE, Silvestri G
Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in SimianImmunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection.
J Immunol. 2015 Oct 1;195(7):3237-47. doi: 10.4049/jimmunol.1402701. Epub 2015Aug 21. 2015.

Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G
Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versusProgressor Simian Immunodeficiency Virus-Infected Macaques.
J Virol. 2015 Sep;89(17):8677-86. doi: 10.1128/JVI.00869-15. Epub 2015 Jun 10. 2015.

Cole SW, Capitanio JP, Chun K, Arevalo JM, Ma J, Cacioppo JT
Myeloid differentiation architecture of leukocyte transcriptome dynamics inperceived social isolation.
Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15142-7. doi:10.1073/pnas.1514249112. Epub 2015 Nov 23. 2015.

Courtney CL, Ethun KF, Villinger F, Ruprecht RM, Byrareddy SN
Massive occlusive thrombosis of the pulmonary artery in pigtailed macaqueschronically infected with R5-tropic simian-human immunodeficiency virus.
J Med Primatol. 2015 Feb;44(1):35-9. doi: 10.1111/jmp.12142. Epub 2014 Sep 1. 2015.

Del Prete GQ, Oswald K, Lara A, Shoemaker R, Smedley J, Macallister R, Coalter V, Wiles A, Wiles R, Li Y, Fast R, Kiser R, Lu B, Zheng J, Alvord WG, Trubey CM, Piatak M Jr, Deleage C, Keele BF, Estes JD, Hesselgesser J, Geleziunas R, Lifson JD
Elevated Plasma Viral Loads in Romidepsin-Treated Simian ImmunodeficiencyVirus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy.
Antimicrob Agents Chemother. 2015 Dec 28;60(3):1560-72. doi:10.1128/AAC.02625-15. 2015.

Elliott ST, Wetzel KS, Francella N, Bryan S, Romero DC, Riddick NE, Shaheen F, Vanderford T, Derdeyn CA, Silvestri G, Paiardini M, Collman RG
Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of SootyMangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV.
J Virol. 2015 Sep;89(18):9252-61. doi: 10.1128/JVI.01236-15. Epub 2015 Jun 24. 2015.

Felsburg PJ, De Ravin SS, Malech HL, Sorrentino BP, Burtner C, Kiem HP
Gene therapy studies in a canine model of X-linked severe combinedimmunodeficiency.
Hum Gene Ther Clin Dev. 2015 Mar;26(1):50-6. doi: 10.1089/humc.2015.004. Epub2015 Feb 24. 2015.

Fernandez-Romero JA, Deal C, Herold BC, Schiller J, Patton D, Zydowsky T, Romano J, Petro CD, Narasimhan M
Multipurpose prevention technologies: the future of HIV and STI protection.
Trends Microbiol. 2015 Jul;23(7):429-436. doi: 10.1016/j.tim.2015.02.006. Epub2015 Mar 7. 2015.

Fukazawa Y, Lum R, Okoye AA, Park H, Matsuda K, Bae JY, Hagen SI, Shoemaker R, Deleage C, Lucero C, Morcock D, Swanson T, Legasse AW, Axthelm MK, Hesselgesser J, Geleziunas R, Hirsch VM, Edlefsen PT, Piatak M Jr, Estes JD, Lifson JD, Picker LJ
B cell follicle sanctuary permits persistent productive simian immunodeficiencyvirus infection in elite controllers.
Nat Med. 2015 Feb;21(2):132-9. doi: 10.1038/nm.3781. Epub 2015 Jan 19. 2015.

Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M
AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. 2015.

Greenwood EJ, Schmidt F, Kondova I, Niphuis H, Hodara VL, Clissold L, McLay K, Guerra B, Redrobe S, Giavedoni LD, Lanford RE, Murthy KK, Rouet F, Heeney JL
Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) SharesFeatures of Both Pathogenic and Non-pathogenic Lentiviral Infections.
PLoS Pathog. 2015 Sep 11;11(9):e1005146. doi: 10.1371/journal.ppat.1005146.eCollection 2015 Sep. 2015.

Grow EJ, Flynn RA, Chavez SL, Bayless NL, Wossidlo M, Wesche DJ, Martin L, Ware CB, Blish CA, Chang HY, Pera RA, Wysocka J
Intrinsic retroviral reactivation in human preimplantation embryos andpluripotent cells.
Nature. 2015 Jun 11;522(7555):221-5. doi: 10.1038/nature14308. Epub 2015 Apr 20. 2015.

Gupta S, Pegu P, Venzon DJ, Gach JS, Ma ZM, Landucci G, Miller CJ, Franchini G, Forthal DN
Enhanced in vitro transcytosis of simian immunodeficiency virus mediated byvaccine-induced antibody predicts transmitted/founder strain number after rectal challenge.
J Infect Dis. 2015 Jan 1;211(1):45-52. doi: 10.1093/infdis/jiu300. Epub 2014 May 21. 2015.

Gustin JK, Bai Y, Moses AV, Douglas JL
Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin.
J Infect Dis. 2015 Oct 1;212 Suppl 2:S181-90. doi: 10.1093/infdis/jiv125. Epub2015 Mar 27. 2015.

Irvine C, Egan KJ, Shubber Z, Van Rompay KK, Beanland RL, Ford N
Efficacy of HIV Postexposure Prophylaxis: Systematic Review and Meta-analysis of Nonhuman Primate Studies.
Clin Infect Dis. 2015 Jun 1;60 Suppl 3:S165-9. doi: 10.1093/cid/civ069. 2015.

Jiang AP, Jiang JF, Wei JF, Guo MG, Qin Y, Guo QQ, Ma L, Liu BC, Wang X, Veazey RS, Ding YB, Wang JH
Human Mucosal Mast Cells Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells.
J Virol. 2015 Dec 30;90(6):2928-37. doi: 10.1128/JVI.03008-15. 2015.

Kaliyaperumal S, Wuthrich C, Westmoreland SV, Koralnik IJ
Simian Virus 40 Infection in the Spinal Cord of Simian ImmunodeficiencyVirus-Immunosuppressed Rhesus Macaques.
J Neuropathol Exp Neurol. 2015 Nov;74(11):1071-6. doi:10.1097/NEN.0000000000000252. 2015.

Kalokhe AS, Adekambi T, Ibegbu CC, Ray SM, Day CL, Rengarajan J
Impaired degranulation and proliferative capacity of Mycobacteriumtuberculosis-specific CD8+ T cells in HIV-infected individuals with latent tuberculosis.
J Infect Dis. 2015 Feb 15;211(4):635-40. doi: 10.1093/infdis/jiu505. Epub 2014Sep 9. 2015.

Kang C, Huang Y, Miller CJ
A discrete-time survival model with random effects for designing and analyzingrepeated low-dose challenge experiments.
Biostatistics. 2015 Apr;16(2):295-310. doi: 10.1093/biostatistics/kxu040. Epub2014 Sep 3. 2015.

Katz PS, Siggins RW, Porretta C, Armstrong ML, Zea AH, Mercante DE, Parsons C, Veazey RS, Bagby GJ, Nelson S, Molina PE, Welsh DA
Chronic alcohol increases CD8+ T-cell immunosenescence in simian immunodeficiencyvirus-infected rhesus macaques.
Alcohol. 2015 Dec;49(8):759-65. doi: 10.1016/j.alcohol.2015.09.003. Epub 2015 Oct27. 2015.

Khamaikawin W, Saoin S, Nangola S, Chupradit K, Sakkhachornphop S, Hadpech S, Onlamoon N, Ansari AA, Byrareddy SN, Boulanger P, Hong SS, Torbett BE, Tayapiwatana C
Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting TwoDistinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly.
Mol Ther Nucleic Acids. 2015 Aug 25;4:e249. doi: 10.1038/mtna.2015.22. 2015.

Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, Collman RG, Amara RR, Derdeyn CA
Characterization and Implementation of a Diverse Simian Immunodeficiency VirusSIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.
J Virol. 2015 Aug;89(16):8130-51. doi: 10.1128/JVI.01221-14. Epub 2015 May 27. 2015.

Kim WK, McGary CM, Holder GE, Filipowicz AR, Kim MM, Beydoun HA, Cai Y, Liu X, Sugimoto C, Kuroda MJ
Increased Expression of CD169 on Blood Monocytes and Its Regulation by Virus and CD8 T Cells in Macaque Models of HIV Infection and AIDS.
AIDS Res Hum Retroviruses. 2015 Jul;31(7):696-706. doi: 10.1089/AID.2015.0003.Epub 2015 May 11. 2015.

Konadu KA, Chu J, Huang MB, Amancha PK, Armstrong W, Powell MD, Villinger F, Bond VC
Association of Cytokines With Exosomes in the Plasma of HIV-1-SeropositiveIndividuals.
J Infect Dis. 2015 Jun 1;211(11):1712-6. doi: 10.1093/infdis/jiu676. Epub 2014Dec 15. 2015.

Kwa S, Sadagopal S, Shen X, Hong JJ, Gangadhara S, Basu R, Victor B, Iyer SS, LaBranche CC, Montefiori DC, Tomaras GD, Villinger F, Moss B, Kozlowski PA, Amara RR
CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus(SIV) vaccine enhances protection against neutralization-resistant mucosal SIV infection.
J Virol. 2015 Apr;89(8):4690-5. doi: 10.1128/JVI.03527-14. Epub 2015 Feb 4. 2015.

Li CX, Herndon JG, Novembre FJ, Zhang X
A longitudinal magnetization transfer imaging evaluation of brain injury in amacaque model of neuroAIDS.
AIDS Res Hum Retroviruses. 2015 Mar;31(3):335-41. doi: 10.1089/aid.2014.0166.Epub 2014 Nov 6. 2015.

Li H, Evans TI, Gillis J, Connole M, Reeves RK
Bone marrow-imprinted gut-homing of plasmacytoid dendritic cells (pDCs) in acute simian immunodeficiency virus infection results in massive accumulation of hyperfunctional CD4+ pDCs in the mucosae.
J Infect Dis. 2015 Jun 1;211(11):1717-25. doi: 10.1093/infdis/jiu671. Epub 2014Dec 8. 2015.

Ma ZM, Miller CJ
Immunophenotype of simian immunodeficiency virus-infected cells in the spleen of a rhesus monkey.
AIDS Res Hum Retroviruses. 2015 Apr;31(4):359-60. doi: 10.1089/aid.2014.0343.Epub 2015 Mar 11. 2015.

Martins MA, Tully DC, Cruz MA, Power KA, Veloso de Santana MG, Bean DJ, Ogilvie CB, Gadgil R, Lima NS, Magnani DM, Ejima K, Allison DB, Piatak M Jr, Altman JD, Parks CL, Rakasz EG, Capuano S 3rd, Galler R, Bonaldo MC, Lifson JD, Allen TM, Watkins DI
Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell ResponsesFocused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.
J Virol. 2015 Nov;89(21):10802-20. doi: 10.1128/JVI.01440-15. Epub 2015 Aug 19. 2015.

Miles B, Miller SM, Folkvord JM, Kimball A, Chamanian M, Meditz AL, Arends T, McCarter MD, Levy DN, Rakasz EG, Skinner PJ, Connick E
Follicular regulatory T cells impair follicular T helper cells in HIV and SIVinfection.
Nat Commun. 2015 Oct 20;6:8608. doi: 10.1038/ncomms9608. 2015.

Mir KD, Mavigner M, Wang C, Paiardini M, Sodora DL, Chahroudi AM, Bosinger SE, Silvestri G
Reduced Simian Immunodeficiency Virus Replication in Macrophages of SootyMangabeys Is Associated with Increased Expression of Host Restriction Factors.
J Virol. 2015 Oct;89(20):10136-44. doi: 10.1128/JVI.00710-15. Epub 2015 Jul 22. 2015.

Mohan M, Kumar V, Lackner AA, Alvarez X
Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immuneactivation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques.
J Immunol. 2015 Jan 1;194(1):291-306. doi: 10.4049/jimmunol.1401447. Epub 2014Dec 1. 2015.

Mohns MS, Greene JM, Cain BT, Pham NH, Gostick E, Price DA, O'Connor DH
Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines fromSIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer.
J Virol. 2015 Oct;89(19):9748-57. doi: 10.1128/JVI.00993-15. Epub 2015 Jul 15. 2015.

Moniuszko M, Liyanage NP, Doster MN, Parks RW, Grubczak K, Lipinska D, McKinnon K, Brown C, Hirsch V, Vaccari M, Gordon S, Pegu P, Fenizia C, Flisiak R, Grzeszczuk A, Dabrowska M, Robert-Guroff M, Silvestri G, Stevenson M, McCune J, Franchini G
Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir.
AIDS Res Hum Retroviruses. 2015 Jan;31(1):115-26. doi: 10.1089/AID.2013.0220. 2015.

Nakatani-Webster E, Hu SL, Atkins WM, Catalano CE
Assembly and characterization of gp160-nanodiscs: A new platform for biochemical characterization of HIV envelope spikes.
J Virol Methods. 2015 Dec 15;226:15-24. doi: 10.1016/j.jviromet.2015.09.011. Epub2015 Sep 28. 2015.

O'Connell KE, Guo W, Serra C, Beck M, Wachtman L, Hoggatt A, Xia D, Pearson C, Knight H, O'Connell M, Miller AD, Westmoreland SV, Bhasin S
The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenilesimian immunodeficiency virus-infected rhesus macaques.
FASEB J. 2015 Apr;29(4):1165-75. doi: 10.1096/fj.14-257543. Epub 2014 Dec 2. 2015.

Pallikkuth S, Mohan M
Adipose Tissue: Sanctuary for HIV/SIV Persistence and Replication.
Trends Microbiol. 2015 Dec;23(12):748-750. doi: 10.1016/j.tim.2015.11.001. Epub2015 Nov 14. 2015.

Phillips BL, Mehra S, Ahsan MH, Selman M, Khader SA, Kaushal D
LAG3 expression in active Mycobacterium tuberculosis infections.
Am J Pathol. 2015 Mar;185(3):820-33. doi: 10.1016/j.ajpath.2014.11.003. Epub 2014Dec 27. 2015.

Reeves RK, Burgener A, Klatt NR
Targeting the gastrointestinal tract to develop novel therapies for HIV.
Clin Pharmacol Ther. 2015 Oct;98(4):381-6. doi: 10.1002/cpt.186. Epub 2015 Aug21. 2015.

Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH
Antigen-specific NK cell memory in rhesus macaques.
Nat Immunol. 2015 Sep;16(9):927-32. doi: 10.1038/ni.3227. Epub 2015 Jul 20. 2015.

Santangelo PJ, Rogers KA, Zurla C, Blanchard EL, Gumber S, Strait K, Connor-Stroud F, Schuster DM, Amancha PK, Hong JJ, Byrareddy SN, Hoxie JA, Vidakovic B, Ansari AA, Hunter E, Villinger F
Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviraltherapy-treated macaques.
Nat Methods. 2015 May;12(5):427-32. doi: 10.1038/nmeth.3320. Epub 2015 Mar 9. 2015.

Schafer JL, Li H, Evans TI, Estes JD, Reeves RK
Accumulation of Cytotoxic CD16+ NK Cells in Simian ImmunodeficiencyVirus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy.
J Virol. 2015 Jul;89(13):6887-94. doi: 10.1128/JVI.00660-15. Epub 2015 Apr 22. 2015.

Schafer JL, Ries M, Guha N, Connole M, Colantonio AD, Wiertz EJ, Wilson NA, Kaur A, Evans DT
Suppression of a Natural Killer Cell Response by Simian Immunodeficiency VirusPeptides.
PLoS Pathog. 2015 Sep 2;11(9):e1005145. doi: 10.1371/journal.ppat.1005145.eCollection 2015 Sep. 2015.

Schell JB, Bahl K, Folta-Stogniew E, Rose N, Buonocore L, Marx PA, Gambhira R, Rose JK
Antigenic requirement for Gag in a vaccine that protects against high-dosemucosal challenge with simian immunodeficiency virus.
Virology. 2015 Feb;476:405-412. doi: 10.1016/j.virol.2014.12.027. Epub 2015 Jan12. 2015.

Shen X, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara RR, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK, Pavlakis GN, Pantaleo G, Korber BT, Montefiori DC, Tomaras GD
Vaccine-Induced Linear Epitope-Specific Antibodies to Simian ImmunodeficiencyVirus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.
J Virol. 2015 Aug;89(16):8643-50. doi: 10.1128/JVI.03635-14. Epub 2015 May 27. 2015.

Sholukh AM, Watkins JD, Vyas HK, Gupta S, Lakhashe SK, Thorat S, Zhou M, Hemashettar G, Bachler BC, Forthal DN, Villinger F, Sattentau QJ, Weiss RA, Agatic G, Corti D, Lanzavecchia A, Heeney JL, Ruprecht RM
Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemicIgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.
Vaccine. 2015 Apr 21;33(17):2086-95. doi: 10.1016/j.vaccine.2015.02.020. Epub2015 Mar 11. 2015.

Shytaj IL, Nickel G, Arts E, Farrell N, Biffoni M, Pal R, Chung HK, LaBranche C, Montefiori D, Vargas-Inchaustegui D, Robert-Guroff M, Lewis MG, Sacha JB, Palamara AT, Savarino A
Two-Year Follow-Up of Macaques Developing Intermittent Control of the HumanImmunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection.
J Virol. 2015 Aug;89(15):7521-35. doi: 10.1128/JVI.00396-15. Epub 2015 May 13. 2015.

Tchakoute CT, Hesseling AC, Kidzeru EB, Gamieldien H, Passmore JA, Jones CE, Gray CM, Sodora DL, Jaspan HB
Delaying BCG vaccination until 8 weeks of age results in robust BCG-specificT-cell responses in HIV-exposed infants.
J Infect Dis. 2015 Feb 1;211(3):338-46. doi: 10.1093/infdis/jiu434. Epub 2014 Aug8. 2015.

Thippeshappa R, Tian B, Cleveland B, Guo W, Polacino P, Hu SL
Oral Immunization with Recombinant Vaccinia Virus Prime and Intramuscular ProteinBoost Provides Protection against Intrarectal Simian-Human Immunodeficiency Virus Challenge in Macaques.
Clin Vaccine Immunol. 2015 Dec 30;23(3):204-12. doi: 10.1128/CVI.00597-15. 2015.

Trevejo-Nunez G, Chen K, Dufour JP, Bagby GJ, Horne WT, Nelson S, Kolls JK
Ethanol impairs mucosal immunity against Streptococcus pneumoniae infection bydisrupting interleukin 17 gene expression.
Infect Immun. 2015 May;83(5):2082-8. doi: 10.1128/IAI.02869-14. Epub 2015 Mar 9. 2015.

Vishwanathan SA, Burgener A, Bosinger SE, Tharp GK, Guenthner PC, Patel NB, Birse K, Hanson DL, Westmacott GR, Henning TR, Radzio J, Garcia-Lerma JG, Ball TB, McNicholl JM, Kersh EN
Cataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle ofPig-Tailed Macaques by Using a Systems Biology Approach.
J Virol. 2015 Sep;89(18):9167-77. doi: 10.1128/JVI.00263-15. Epub 2015 Jun 24. 2015.

von Bredow B, Arias JF, Heyer LN, Gardner MR, Farzan M, Rakasz EG, Evans DT
Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.
J Virol. 2015 Oct;89(20):10648-55. doi: 10.1128/JVI.01911-15. Epub 2015 Aug 12. 2015.

Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM
Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17Dynamics in SIV-Infected Macaques.
Cell Rep. 2015 Nov 24;13(8):1589-97. doi: 10.1016/j.celrep.2015.10.026. Epub 2015Nov 12. 2015.

Walter L, Ansari AA
MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection.
Front Immunol. 2015 Oct 21;6:540. doi: 10.3389/fimmu.2015.00540. eCollection2015. 2015.

Warren WC, Jasinska AJ, Garcia-Perez R, Svardal H, Tomlinson C, Rocchi M, Archidiacono N, Capozzi O, Minx P, Montague MJ, Kyung K, Hillier LW, Kremitzki M, Graves T, Chiang C, Hughes J, Tran N, Huang Y, Ramensky V, Choi OW, Jung YJ, Schmitt CA, Juretic N, Wasserscheid J, Turner TR, Wiseman RW, Tuscher JJ, Karl JA, Schmitz JE, Zahn R, O'Connor DH, Redmond E, Nisbett A, Jacquelin B, Muller-Trutwin MC, Brenchley JM, Dione M, Antonio M, Schroth GP, Kaplan JR, Jorgensen MJ, Thomas GW, Hahn MW, Raney BJ, Aken B, Nag R, Schmitz J, Churakov G, Noll A, Stanyon R, Webb D, Thibaud-Nissen F, Nordborg M, Marques-Bonet T, Dewar K, Weinstock GM, Wilson RK, Freimer NB
The genome of the vervet (Chlorocebus aethiops sabaeus).
Genome Res. 2015 Dec;25(12):1921-33. doi: 10.1101/gr.192922.115. Epub 2015 Sep16. 2015.

Xu H, Wang X, Lackner AA, Veazey RS
Type 3 innate lymphoid cell depletion is mediated by TLRs in lymphoid tissues of simian immunodeficiency virus-infected macaques.
FASEB J. 2015 Dec;29(12):5072-80. doi: 10.1096/fj.15-276477. Epub 2015 Aug 17. 2015.

Xu H, Wang X, Malam N, Lackner AA, Veazey RS
Persistent Simian Immunodeficiency Virus Infection Causes Ultimate Depletion ofFollicular Th Cells in AIDS.
J Immunol. 2015 Nov 1;195(9):4351-7. doi: 10.4049/jimmunol.1501273. Epub 2015 Sep25. 2015.

Younan PM, Peterson CW, Polacino P, Kowalski JP, Obenza W, Miller HW, Milless BP, Gafken P, DeRosa SC, Hu SL, Kiem HP
Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired inSHIV-infected, ART-treated Nonhuman Primates.
Mol Ther. 2015 May;23(5):943-951. doi: 10.1038/mt.2015.19. Epub 2015 Feb 4. 2015.

Younan PM, Polacino P, Kowalski JP, Hu SL, Kiem HP
Combinatorial hematopoietic stem cell transplantation and vaccination reducesviral pathogenesis following SHIV89.6P-challenge.
Gene Ther. 2015 Dec;22(12):1007-12. doi: 10.1038/gt.2015.83. Epub 2015 Sep 10. 2015.

Yu H, Khalid M, Heigele A, Schmokel J, Usmani SM, van der Merwe J, Munch J, Silvestri G, Kirchhoff F
Lentiviral Nef proteins manipulate T cells in a subset-specific manner.
J Virol. 2015 Feb;89(4):1986-2001. doi: 10.1128/JVI.03104-14. Epub 2014 Dec 10. 2015.

2014

Abdel-Motal UM, Harbison C, Han T, Pudney J, Anderson DJ, Zhu Q, Westmoreland S, Marasco WA
Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaquelower genital tract by AAV gene transfer.
Gene Ther. 2014 Sep;21(9):802-10. doi: 10.1038/gt.2014.56. Epub 2014 Jun 26. 2014.

Abdulhaqq SA, Martinez MI, Kang G, Foulkes AS, Rodriguez IV, Nichols SM, Hunter M, Sariol CA, Ruiz LA, Ross BN, Yin X, Speicher DW, Haase AT, Marx PA, Li Q, Kraiselburd EN, Montaner LJ
Serial cervicovaginal exposures with replication-deficient SIVsm induce higherdendritic cell (pDC) and CD4+ T-cell infiltrates not associated with prevention but a more severe SIVmac251 infection of rhesus macaques.
J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):405-13. doi:10.1097/QAI.0000000000000047. 2014.

Al-Harthi L, Buch S, Geiger JD, Gendelman HE, He JJ, Jordan-Sciutto KL, Kolson DL, Rappaport J, Roy S, Zheng J, Fox HS
Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium.
J Neuroimmune Pharmacol. 2014 Jun;9(3):269-76. doi: 10.1007/s11481-014-9545-1.Epub 2014 May 2. 2014.

Alvarez X, Midkiff C, Kuroda MJ, Mohan M, Lackner AA
Detecting the simian immunodeficiency virus reservoir as viral DNA and RNA insitu simultaneously as a model to monitor viral latency.
AIDS Res Hum Retroviruses. 2014 Mar;30(3):205-6. doi: 10.1089/aid.2014.0024. 2014.

Ambrose Z, Kline C, Polacino P, Hu SL
Dysregulation of multiple inflammatory molecules in lymph node and ileum ofmacaques during RT-SHIV infection with or without antiretroviral therapy.
J Med Primatol. 2014 Oct;43(5):298-309. doi: 10.1111/jmp.12126. Epub 2014 May 2. 2014.

Amedee AM, Veazey R, Molina P, Nelson S, Bagby GJ
Chronic binge alcohol increases susceptibility to rectal simian immunodeficiency virus infection in macaques.
AIDS. 2014 Oct 23;28(16):2485-7. doi: 10.1097/QAD.0000000000000413. 2014.

Andrews CD, Spreen WR, Mohri H, Moss L, Ford S, Gettie A, Russell-Lodrigue K, Bohm RP, Cheng-Mayer C, Hong Z, Markowitz M, Ho DD
Long-acting integrase inhibitor protects macaques from intrarectal simian/humanimmunodeficiency virus.
Science. 2014 Mar 7;343(6175):1151-4. doi: 10.1126/science.1248707. Epub 2014 Mar4. 2014.

Antoine P, Varner V, Carville A, Connole M, Marchant A, Kaur A
Postnatal acquisition of primary rhesus cytomegalovirus infection is associatedwith prolonged virus shedding and impaired CD4+ T lymphocyte function.
J Infect Dis. 2014 Oct 1;210(7):1090-9. doi: 10.1093/infdis/jiu215. Epub 2014 Apr8. 2014.

Arrode-Bruses G, Moussa M, Baccard-Longere M, Villinger F, Chebloune Y
Long-term central and effector SHIV-specific memory T cell responses elicitedafter a single immunization with a novel lentivector DNA vaccine.
PLoS One. 2014 Oct 22;9(10):e110883. doi: 10.1371/journal.pone.0110883.eCollection 2014. 2014.

Barnable P, Calenda G, Ouattara L, Gettie A, Blanchard J, Jean-Pierre N, Kizima L, Rodriguez A, Abraham C, Menon R, Seidor S, Cooney ML, Roberts KD, Sperling R, Piatak M Jr, Lifson JD, Fernandez-Romero JA, Zydowsky TM, Robbiani M, Teleshova N
A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginalexplants.
PLoS One. 2014 Sep 26;9(9):e108109. doi: 10.1371/journal.pone.0108109.eCollection 2014. 2014.

Barouch DH, Picker LJ
Novel vaccine vectors for HIV-1.
Nat Rev Microbiol. 2014 Nov;12(11):765-71. doi: 10.1038/nrmicro3360. Epub 2014Oct 8. 2014.

Barrenas F, Palermo RE, Agricola B, Agy MB, Aicher L, Carter V, Flanary L, Green RR, McLain R, Li Q, Lu W, Murnane R, Peng X, Thomas MJ, Weiss JM, Anderson DM, Katze MG
Deep transcriptional sequencing of mucosal challenge compartment from rhesusmacaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activation.
J Virol. 2014 Jul;88(14):7962-72. doi: 10.1128/JVI.00543-14. Epub 2014 May 7. 2014.

Burwitz BJ, Wu HL, Reed JS, Hammond KB, Newman LP, Bimber BN, Nimiyongskul FA, Leon EJ, Maness NJ, Friedrich TC, Yokoyama M, Sato H, Matano T, O'Connor DH, Sacha JB
Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatorymutations following transmission of simian immunodeficiency virus.
J Virol. 2014 Mar;88(6):3598-604. doi: 10.1128/JVI.03304-13. Epub 2013 Dec 26. 2014.

Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, Villinger T, Little D, Parslow TG, Santangelo PJ, Villinger F, Fauci AS, Ansari AA
Targeting alpha4beta7 integrin reduces mucosal transmission of simianimmunodeficiency virus and protects gut-associated lymphoid tissue from infection.
Nat Med. 2014 Dec;20(12):1397-400. doi: 10.1038/nm.3715. Epub 2014 Nov 24. 2014.

Carbonaro Sarracino D, Tarantal AF, Lee CC, Martinez M, Jin X, Wang X, Hardee CL, Geiger S, Kahl CA, Kohn DB
Effects of vector backbone and pseudotype on lentiviral vector-mediated genetransfer: studies in infant ADA-deficient mice and rhesus monkeys.
Mol Ther. 2014 Oct;22(10):1803-16. doi: 10.1038/mt.2014.88. Epub 2014 Jun 13. 2014.

Cartwright EK, McGary CS, Cervasi B, Micci L, Lawson B, Elliott ST, Collman RG, Bosinger SE, Paiardini M, Vanderford TH, Chahroudi A, Silvestri G
Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simianimmunodeficiency virus infections.
J Immunol. 2014 May 15;192(10):4666-73. doi: 10.4049/jimmunol.1303193. Epub 2014 Apr 11. 2014.

Clarke DK, Nasar F, Chong S, Johnson JE, Coleman JW, Lee M, Witko SE, Kotash CS, Abdullah R, Megati S, Luckay A, Nowak B, Lackner A, Price RE, Little P, Kalyan N, Randolf V, Javadian A, Zamb TJ, Parks CL, Egan MA, Eldridge J, Hendry M, Udem SA
Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates.
J Virol. 2014 Jun;88(12):6690-701. doi: 10.1128/JVI.03441-13. Epub 2014 Apr 2. 2014.

Connick E, Folkvord JM, Lind KT, Rakasz EG, Miles B, Wilson NA, Santiago ML, Schmitt K, Stephens EB, Kim HO, Wagstaff R, Li S, Abdelaal HM, Kemp N, Watkins DI, MaWhinney S, Skinner PJ
Compartmentalization of simian immunodeficiency virus replication withinsecondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.
J Immunol. 2014 Dec 1;193(11):5613-25. doi: 10.4049/jimmunol.1401161. Epub 2014Oct 31. 2014.

Curtis K, Rollins M, Carryl H, Bradshaw K, Van Rompay KK, Abel K, Burke MW
Reduction of pyramidal and immature hippocampal neurons in pediatric simianimmunodeficiency virus infection.
Neuroreport. 2014 Sep 10;25(13):973-8. doi: 10.1097/WNR.0000000000000148. 2014.

Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW
Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART.
PLoS One. 2014 Feb 5;9(2):e87914. doi: 10.1371/journal.pone.0087914. eCollection 2014. 2014.

Del Prete GQ, Park H, Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Kahl C, Piatak M Jr, Quinones OA, Alvord WG, Smedley J, Estes JD, Lifson JD, Picker LJ, Keele BF
Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm fortracking independent infection events.
J Virol. 2014 Jul;88(14):8077-90. doi: 10.1128/JVI.01026-14. Epub 2014 May 7. 2014.

Dodd T, Simon L, LeCapitaine NJ, Zabaleta J, Mussell J, Berner P, Ford S, Dufour J, Bagby GJ, Nelson S, Molina PE
Chronic binge alcohol administration accentuates expression of pro-fibrotic andinflammatory genes in the skeletal muscle of simian immunodeficiency virus-infected macaques.
Alcohol Clin Exp Res. 2014 Nov;38(11):2697-706. doi: 10.1111/acer.12545. 2014.

Ericsen AJ, Starrett GJ, Greene JM, Lauck M, Raveendran M, Deiros DR, Mohns MS, Vince N, Cain BT, Pham NH, Weinfurter JT, Bailey AL, Budde ML, Wiseman RW, Gibbs R, Muzny D, Friedrich TC, Rogers J, O'Connor DH
Whole genome sequencing of SIV-infected macaques identifies candidate loci thatmay contribute to host control of virus replication.
Genome Biol. 2014 Nov 7;15(11):478. doi: 10.1186/s13059-014-0478-z. 2014.

Estep RD, Rawlings SD, Li H, Manoharan M, Blaine ET, O'Connor MA, Messaoudi I, Axthelm MK, Wong SW
The rhesus rhadinovirus CD200 homologue affects immune responses and viral loads during in vivo infection.
J Virol. 2014 Sep;88(18):10635-54. doi: 10.1128/JVI.01276-14. Epub 2014 Jul 2. 2014.

Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, Ishii N, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells duringsimian immunodeficiency virus infection in rhesus macaques.
J Immunol. 2014 Dec 1;193(11):5576-83. doi: 10.4049/jimmunol.1400961. Epub 2014Oct 27. 2014.

Fuller DH, Richert-Spuhler LE, Klatt NR
HIV vaccine trial exploits a dual and central role for innate immunity.
J Virol. 2014 Oct;88(20):11640-3. doi: 10.1128/JVI.02140-14. Epub 2014 Aug 13. 2014.

Gambhira R, Keele BF, Schell JB, Hunter MJ, Dufour JP, Montefiori DC, Tang H, Rose JK, Rose N, Marx PA
Transmitted/founder simian immunodeficiency virus envelope sequences in vesicularstomatitis and Semliki forest virus vector immunized rhesus macaques.
PLoS One. 2014 Oct 31;9(10):e109678. doi: 10.1371/journal.pone.0109678.eCollection 2014. 2014.

Gaulke CA, Porter M, Han YH, Sankaran-Walters S, Grishina I, George MD, Dang AT, Ding SW, Jiang G, Korf I, Dandekar S
Intestinal epithelial barrier disruption through altered mucosal microRNAexpression in human immunodeficiency virus and simian immunodeficiency virus infections.
J Virol. 2014 Jun;88(11):6268-80. doi: 10.1128/JVI.00097-14. Epub 2014 Mar 26. 2014.

George MD, Hu W, Billingsley JM, Reeves RK, Sankaran-Walters S, Johnson RP, Dandekar S
Transcriptional profiling of peripheral CD8+T cell responses to SIVDeltanef andSIVmac251 challenge reveals a link between protective immunity and induction of systemic immunoregulatory mechanisms.
Virology. 2014 Nov;468-470:581-591. doi: 10.1016/j.virol.2014.09.013. Epub 2014Oct 1. 2014.

Goode D, Truong R, Villegas G, Calenda G, Guerra-Perez N, Piatak M, Lifson JD, Blanchard J, Gettie A, Robbiani M, Martinelli E
HSV-2-driven increase in the expression of alpha4beta7 correlates with increased susceptibility to vaginal SHIV(SF162P3) infection.
PLoS Pathog. 2014 Dec 18;10(12):e1004567. doi: 10.1371/journal.ppat.1004567.eCollection 2014 Dec. 2014.

Gooneratne SL, Alinejad-Rokny H, Ebrahimi D, Bohn PS, Wiseman RW, O'Connor DH, Davenport MP, Kent SJ
Linking pig-tailed macaque major histocompatibility complex class I haplotypesand cytotoxic T lymphocyte escape mutations in simian immunodeficiency virus infection.
J Virol. 2014 Dec;88(24):14310-25. doi: 10.1128/JVI.02428-14. Epub 2014 Oct 1. 2014.

Greene JM, Weiler AM, Reynolds MR, Cain BT, Pham NH, Ericsen AJ, Peterson EJ, Crosno K, Brunner K, Friedrich TC, O'Connor DH
Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensedchallenge window.
Retrovirology. 2014 Aug 14;11:66. doi: 10.1186/s12977-014-0066-z. 2014.

Hadzic SV, Wang X, Dufour J, Doyle L, Marx PA, Lackner AA, Paulsen DB, Veazey RS
Comparison of the vaginal environment of Macaca mulatta and Macaca nemestrinathroughout the menstrual cycle.
Am J Reprod Immunol. 2014 Apr;71(4):322-9. doi: 10.1111/aji.12201. Epub 2014 Feb 13. 2014.

Harbison C, Zhuang K, Gettie A, Blanchard J, Knight H, Didier P, Cheng-Mayer C, Westmoreland S
Giant cell encephalitis and microglial infection with mucosally transmittedsimian-human immunodeficiency virus SHIVSF162P3N in rhesus macaques.
J Neurovirol. 2014 Feb;20(1):62-72. doi: 10.1007/s13365-013-0229-z. Epub 2014 Jan25. 2014.

Hong JJ, Amancha PK, Rogers KA, Courtney CL, Havenar-Daughton C, Crotty S, Ansari AA, Villinger F
Early lymphoid responses and germinal center formation correlate with lower viralload set points and better prognosis of simian immunodeficiency virus infection.
J Immunol. 2014 Jul 15;193(2):797-806. doi: 10.4049/jimmunol.1400749. Epub 2014Jun 6. 2014.

Hong JJ, Villinger F, Courtney CL
PAS-positive extracellular deposits within germinal centers of hyperplasticfollicles during SIV infection in a rhesus macaque.
J Med Primatol. 2014 Oct;43(5):374-7. doi: 10.1111/jmp.12109. Epub 2014 Mar 14. 2014.

Hsu M, Aravantinou M, Menon R, Seidor S, Goldman D, Kenney J, Derby N, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Fernandez-Romero JA, Zydowsky TM, Robbiani M
A combination microbicide gel protects macaques against vaginal simian humanimmunodeficiency virus-reverse transcriptase infection, but only partially reduces herpes simplex virus-2 infection after a single high-dose cochallenge.
AIDS Res Hum Retroviruses. 2014 Feb;30(2):174-83. doi: 10.1089/aid.2013.0165.Epub 2013 Nov 22. 2014.

Hsu M, Keele BF, Aravantinou M, Krawczyk N, Seidor S, Abraham CJ, Zhang S, Rodriguez A, Kizima L, Derby N, Jean-Pierre N, Mizenina O, Gettie A, Grasperge B, Blanchard J, Piatak MJ Jr, Lifson JD, Fernandez-Romero JA, Zydowsky TM, Robbiani M
Exposure to MIV-150 from a high-dose intravaginal ring results in limitedemergence of drug resistance mutations in SHIV-RT infected rhesus macaques.
PLoS One. 2014 Feb 27;9(2):e89300. doi: 10.1371/journal.pone.0089300. eCollection2014. 2014.

Kannanganant S, Gangadhara S, Lai L, Lawson B, Kozlowski PA, Robinson HL, Amara RR
Local control of repeated-dose rectal challenges in DNA/MVA-vaccinated macaquesprotected against a first series of simian immunodeficiency virus challenges.
J Virol. 2014 May;88(10):5864-9. doi: 10.1128/JVI.00145-14. Epub 2014 Feb 26. 2014.

Kenney J, Derby N, Aravantinou M, Kleinbeck K, Frank I, Gettie A, Grasperge B, Blanchard J, Piatak M Jr, Lifson JD, Zydowsky TM, Robbiani M
Short communication: a repeated simian human immunodeficiency virus reversetranscriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicides.
AIDS Res Hum Retroviruses. 2014 Nov;30(11):1117-24. doi: 10.1089/aid.2014.0207. 2014.

Kenway-Lynch CS, Das A, Lackner AA, Pahar B
Cytokine/Chemokine responses in activated CD4+ and CD8+ T cells isolated fromperipheral blood, bone marrow, and axillary lymph nodes during acute simian immunodeficiency virus infection.
J Virol. 2014 Aug;88(16):9442-57. doi: 10.1128/JVI.00774-14. Epub 2014 Jun 11. 2014.

Kizima L, Rodriguez A, Kenney J, Derby N, Mizenina O, Menon R, Seidor S, Zhang S, Levendosky K, Jean-Pierre N, Pugach P, Villegas G, Ford BE, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Paglini G, Teleshova N, Zydowsky TM, Robbiani M, Fernandez-Romero JA
A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.
PLoS One. 2014 Apr 16;9(4):e94547. doi: 10.1371/journal.pone.0094547. eCollection2014. 2014.

Kwa S, Lai L, Gangadhara S, Siddiqui M, Pillai VB, Labranche C, Yu T, Moss B, Montefiori DC, Robinson HL, Kozlowski PA, Amara RR
CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virusSIV239 vaccine enhances SIV-specific humoral and cellular immunity and improves protection against a heterologous SIVE660 mucosal challenge.
J Virol. 2014 Sep 1;88(17):9579-89. doi: 10.1128/JVI.00975-14. Epub 2014 Jun 11. 2014.

Lakhashe SK, Byrareddy SN, Zhou M, Bachler BC, Hemashettar G, Hu SL, Villinger F, Else JG, Stock S, Lee SJ, Vargas-Inchaustegui DA, Cofano EB, Robert-Guroff M, Johnson WE, Polonis VR, Forthal DN, Loret EP, Rasmussen RA, Ruprecht RM
Multimodality vaccination against clade C SHIV: partial protection againstmucosal challenges with a heterologous tier 2 virus.
Vaccine. 2014 Nov 12;32(48):6527-36. doi: 10.1016/j.vaccine.2014.08.065. Epub2014 Sep 20. 2014.

Lauck M, Switzer WM, Sibley SD, Hyeroba D, Tumukunde A, Weny G, Shankar A, Greene JM, Ericsen AJ, Zheng H, Ting N, Chapman CA, Friedrich TC, Goldberg TL, O'Connor DH
Discovery and full genome characterization of a new SIV lineage infectingred-tailed guenons (Cercopithecus ascanius schmidti) in Kibale National Park, Uganda.
Retrovirology. 2014 Jul 4;11:55. doi: 10.1186/1742-4690-11-55. 2014.

Lee KM, Chiu KB, Renner NA, Sansing HA, Didier PJ, MacLean AG
Form follows function: astrocyte morphology and immune dysfunction in SIVneuroAIDS.
J Neurovirol. 2014 Oct;20(5):474-84. doi: 10.1007/s13365-014-0267-1. Epub 2014Jun 27. 2014.

Li CX, Zhang X, Komery A, Li Y, Mao H, Herndon JG, Novembre FJ
Longitudinal cerebral metabolic changes in pig-tailed macaques infected with the neurovirulent virus SIVsmmFGb.
J Neurovirol. 2014 Dec;20(6):612-9. doi: 10.1007/s13365-014-0286-y. Epub 2014 Nov7. 2014.

Li H, Margolick JB, Bream JH, Nilles TL, Langan S, Bui HT, Sylwester AW, Picker LJ, Leng SX
Heterogeneity of CD4+ and CD8+ T-cell responses to cytomegalovirus inHIV-infected and HIV-uninfected men who have sex with men.
J Infect Dis. 2014 Aug 1;210(3):400-4. doi: 10.1093/infdis/jiu093. Epub 2014 Feb 14. 2014.

Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS, Skinner PJ, Zupancic ML, Carlis JV, Piatak M Jr, Waterman D, Reeves RK, Masek-Hammerman K, Derdeyn CA, Alpert MD, Evans DT, Kohler H, Muller S, Robinson J, Lifson JD, Burton DR, Johnson RP, Haase AT
Live simian immunodeficiency virus vaccine correlate of protection: localantibody production and concentration on the path of virus entry.
J Immunol. 2014 Sep 15;193(6):3113-25. doi: 10.4049/jimmunol.1400820. Epub 2014Aug 18. 2014.

Li X, Price MA, He D, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, Hunter E, Kaslow RA, Gilmour J, Tang J
Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions.
Hum Genet. 2014 Sep;133(9):1187-97. doi: 10.1007/s00439-014-1465-x. Epub 2014 Jun27. 2014.

Liu DX, Gill A, Holman PJ, Didier PJ, Blanchard JL, Veazey RS, Lackner AA
Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with asimian-human immunodeficiency virus.
J Med Primatol. 2014 Jun;43(3):206-8. doi: 10.1111/jmp.12105. Epub 2014 Feb 11. 2014.

Malherbe DC, Pissani F, Sather DN, Guo B, Pandey S, Sutton WF, Stuart AB, Robins H, Park B, Krebs SJ, Schuman JT, Kalams S, Hessell AJ, Haigwood NL
Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.
J Virol. 2014 Nov;88(22):12949-67. doi: 10.1128/JVI.01812-14. Epub 2014 Sep 10. 2014.

Malouli D, Howell GL, Legasse AW, Kahl C, Axthelm MK, Hansen SG, Fruh K
Full genome sequence analysis of a novel adenovirus of rhesus macaque originindicates a new simian adenovirus type and species.
Virol Rep. 2014 Sep;3-4:18-29. doi: 10.1016/j.virep.2014.10.001. 2014.

Mandell DT, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, Haret-Richter G, Xu C, Aamer H, Dufour J, Trichel A, Douek DC, Keele BF, Apetrei C, Pandrea I
Pathogenic features associated with increased virulence upon Simianimmunodeficiency virus cross-species transmission from natural hosts.
J Virol. 2014 Jun;88(12):6778-92. doi: 10.1128/JVI.03785-13. Epub 2014 Apr 2. 2014.

Martins MA, Wilson NA, Piaskowski SM, Weisgrau KL, Furlott JR, Bonaldo MC, Veloso de Santana MG, Rudersdorf RA, Rakasz EG, Keating KD, Chiuchiolo MJ, Piatak M Jr, Allison DB, Parks CL, Galler R, Lifson JD, Watkins DI
Vaccination with Gag, Vif, and Nef gene fragments affords partial control ofviral replication after mucosal challenge with SIVmac239.
J Virol. 2014 Jul;88(13):7493-516. doi: 10.1128/JVI.00601-14. Epub 2014 Apr 16. 2014.

Matrajt L, Younan PM, Kiem HP, Schiffer JT
The majority of CD4+ T-cell depletion during acute simian-human immunodeficiency virus SHIV89.6P infection occurs in uninfected cells.
J Virol. 2014 Mar;88(6):3202-12. doi: 10.1128/JVI.03428-13. Epub 2014 Jan 3. 2014.

Mavigner M, Watkins B, Lawson B, Lee ST, Chahroudi A, Kean L, Silvestri G
Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaquesafter autologous hematopoietic stem cell transplant.
PLoS Pathog. 2014 Sep 25;10(9):e1004406. doi: 10.1371/journal.ppat.1004406.eCollection 2014 Sep. 2014.

McGary CS, Cervasi B, Chahroudi A, Micci L, Taaffe J, Meeker T, Silvestri G, Davenport MP, Paiardini M
Increased stability and limited proliferation of CD4+ central memory T cellsdifferentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques.
J Virol. 2014 Apr;88(8):4533-42. doi: 10.1128/JVI.03515-13. Epub 2014 Feb 5. 2014.

McGary CS, Silvestri G, Paiardini M
Animal models for viral infection and cell exhaustion.
Curr Opin HIV AIDS. 2014 Sep;9(5):492-9. doi: 10.1097/COH.0000000000000093. 2014.

Mohan M, Chandra LC, Torben W, Aye PP, Alvarez X, Lackner AA
miR-190b is markedly upregulated in the intestine in response to simianimmunodeficiency virus replication and partly regulates myotubularin-related protein-6 expression.
J Immunol. 2014 Aug 1;193(3):1301-13. doi: 10.4049/jimmunol.1303479. Epub 2014Jun 30. 2014.

Molina PE, Amedee AM, LeCapitaine NJ, Zabaleta J, Mohan M, Winsauer PJ, Vande Stouwe C, McGoey RR, Auten MW, LaMotte L, Chandra LC, Birke LL
Modulation of gut-specific mechanisms by chronic delta(9)-tetrahydrocannabinoladministration in male rhesus macaques infected with simian immunodeficiency virus: a systems biology analysis.
AIDS Res Hum Retroviruses. 2014 Jun;30(6):567-78. doi: 10.1089/aid.2013.0182.Epub 2014 Feb 7. 2014.

Molina PE, Amedee AM, Veazey R, Dufour J, Volaufova J, Bagby GJ, Nelson S
Chronic binge alcohol consumption does not diminish effectiveness of continuousantiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques.
Alcohol Clin Exp Res. 2014 Sep;38(9):2335-44. doi: 10.1111/acer.12507. 2014.

Monjure CJ, Tatum CD, Panganiban AT, Arainga M, Traina-Dorge V, Marx PA Jr, Didier ES
Optimization of PCR for quantification of simian immunodeficiency virus genomicRNA in plasma of rhesus macaques (Macaca mulatta) using armored RNA.
J Med Primatol. 2014 Feb;43(1):31-43. doi: 10.1111/jmp.12088. Epub 2013 Nov 22. 2014.

Mylvaganam GH, Velu V, Hong JJ, Sadagopal S, Kwa S, Basu R, Lawson B, Villinger F, Amara RR
Diminished viral control during simian immunodeficiency virus infection isassociated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.
J Immunol. 2014 Nov 1;193(9):4527-36. doi: 10.4049/jimmunol.1401222. Epub 2014Sep 22. 2014.

North TW, Villalobos A, Hurwitz SJ, Deere JD, Higgins J, Chatterjee P, Tao S, Kauffman RC, Luciw PA, Kohler JJ, Schinazi RF
Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decaykinetics.
Antimicrob Agents Chemother. 2014 Jul;58(7):3927-33. doi: 10.1128/AAC.02522-14.Epub 2014 Apr 28. 2014.

Ouattara LA, Barnable P, Mawson P, Seidor S, Zydowsky TM, Kizima L, Rodriguez A, Fernandez-Romero JA, Cooney ML, Roberts KD, Gettie A, Blanchard J, Robbiani M, Teleshova N
MIV-150-containing intravaginal rings protect macaque vaginal explants againstSHIV-RT infection.
Antimicrob Agents Chemother. 2014 May;58(5):2841-8. doi: 10.1128/AAC.01529-13.Epub 2014 Mar 10. 2014.

Pan D, Kenway-Lynch CS, Lala W, Veazey RS, Lackner AA, Das A, Pahar B
Lack of interleukin-10-mediated anti-inflammatory signals and upregulatedinterferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection.
J Virol. 2014 Nov;88(22):13015-28. doi: 10.1128/JVI.01757-14. Epub 2014 Aug 27. 2014.

Petrosky KY, Knight HL, Westmoreland SV, Miller AD
Atypical nodular astrocytosis in simian immunodeficiency virus-infected rhesusmacaques (Macaca mulatta).
J Med Primatol. 2014 Dec;43(6):468-76. doi: 10.1111/jmp.12138. Epub 2014 Aug 1. 2014.

Phillips KA, Bales KL, Capitanio JP, Conley A, Czoty PW, 't Hart BA, Hopkins WD, Hu SL, Miller LA, Nader MA, Nathanielsz PW, Rogers J, Shively CA, Voytko ML
Why primate models matter.
Am J Primatol. 2014 Sep;76(9):801-27. doi: 10.1002/ajp.22281. Epub 2014 Apr 10. 2014.

Postler TS, Bixby JG, Desrosiers RC, Yuste E
Systematic analysis of intracellular trafficking motifs located within thecytoplasmic domain of simian immunodeficiency virus glycoprotein gp41.
PLoS One. 2014 Dec 5;9(12):e114753. doi: 10.1371/journal.pone.0114753.eCollection 2014. 2014.

Reeves RK, Kang G, Li H, Li Q
Depletion of lamina propria innate lymphoid cells in simian immunodeficiencyvirus infection.
AIDS Res Hum Retroviruses. 2014 Dec;30(12):1160-1. doi: 10.1089/aid.2014.0293. 2014.

Rodriguez AR, Hodara V, Murthy K, Morrow L, Sanchez M, Bienvenu AE, Murthy KK
T cell interleukin-15 surface expression in chimpanzees infected with humanimmunodeficiency virus.
Cell Immunol. 2014 Mar-Apr;288(1-2):24-30. doi: 10.1016/j.cellimm.2014.01.009.Epub 2014 Feb 6. 2014.

Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, Boritz E, Levin D, Wijeyesinghe S, Makamdop KN, del Prete GQ, Hill BJ, Timmer JK, Reiss E, Yarden G, Darko S, Contijoch E, Todd JP, Silvestri G, Nason M, Norgren RB Jr, Keele BF, Rao S, Langer JA, Lifson JD, Schreiber G, Douek DC
Type I interferon responses in rhesus macaques prevent SIV infection and slowdisease progression.
Nature. 2014 Jul 31;511(7511):601-5. doi: 10.1038/nature13554. Epub 2014 Jul 9. 2014.

Sather DN, Carbonetti S, Malherbe DC, Pissani F, Stuart AB, Hessell AJ, Gray MD, Mikell I, Kalams SA, Haigwood NL, Stamatatos L
Emergence of broadly neutralizing antibodies and viral coevolution in twosubjects during the early stages of infection with human immunodeficiency virus type 1.
J Virol. 2014 Nov;88(22):12968-81. doi: 10.1128/JVI.01816-14. Epub 2014 Aug 13. 2014.

Selinger C, Strbo N, Gonzalez L, Aicher L, Weiss JM, Law GL, Palermo RE, Vaccari M, Franchini G, Podack ER, Katze MG
Multiple low-dose challenges in a rhesus macaque AIDS vaccine trial result in an evolving host response that affects protective outcome.
Clin Vaccine Immunol. 2014 Dec;21(12):1650-60. doi: 10.1128/CVI.00455-14. Epub2014 Oct 1. 2014.

Shang L, Smith AJ, Duan L, Perkey KE, Qu L, Wietgrefe S, Zupancic M, Southern PJ, Masek-Hammerman K, Reeves RK, Johnson RP, Haase AT
NK cell responses to simian immunodeficiency virus vaginal exposure in naive and vaccinated rhesus macaques.
J Immunol. 2014 Jul 1;193(1):277-84. doi: 10.4049/jimmunol.1400417. Epub 2014 Jun4. 2014.

Sharma P, Chennareddi L, Greene-Hartsfield EZ, Villinger F, Cohen JK, Herndon JG
Hematology and serum chemistry values of sooty mangabeys (Cercocebus atys):comparison with rhesus monkeys.
J Med Primatol. 2014 Apr;43(2):78-88. doi: 10.1111/jmp.12091. Epub 2013 Nov 21. 2014.

Sheppard NC, Jones RB, Burwitz BJ, Nimityongskul FA, Newman LP, Buechler MB, Reed JS, Piaskowski SM, Weisgrau KL, Castrovinci PA, Wilson NA, Ostrowski MA, Park B, Nixon DF, Rakasz EG, Sacha JB
Vaccination against endogenous retrotransposable element consensus sequences doesnot protect rhesus macaques from SIVsmE660 infection and replication.
PLoS One. 2014 Mar 20;9(3):e92012. doi: 10.1371/journal.pone.0092012. eCollection2014. 2014.

Sholukh AM, Byrareddy SN, Shanmuganathan V, Hemashettar G, Lakhashe SK, Rasmussen RA, Watkins JD, Vyas HK, Thorat S, Brandstoetter T, Mukhtar MM, Yoon JK, Novembre FJ, Villinger F, Landucci G, Forthal DN, Ratcliffe S, Tuero I, Robert-Guroff M, Polonis VR, Bilska M, Montefiori DC, Johnson WE, Ertl HC, Ruprecht RM
Passive immunization of macaques with polyclonal anti-SHIV IgG against aheterologous tier 2 SHIV: outcome depends on IgG dose.
Retrovirology. 2014 Jan 20;11:8. doi: 10.1186/1742-4690-11-8. 2014.

Siggins RW, Molina P, Zhang P, Bagby GJ, Nelson S, Dufour J, LeCapitaine NJ, Walsh C, Welsh DA
Dysregulation of myelopoiesis by chronic alcohol administration during early SIV infection of rhesus macaques.
Alcohol Clin Exp Res. 2014 Jul;38(7):1993-2000. doi: 10.1111/acer.12433. Epub2014 Jun 18. 2014.

Simon L, LeCapitaine N, Berner P, Vande Stouwe C, Mussell JC, Allerton T, Primeaux SD, Dufour J, Nelson S, Bagby GJ, Cefalu W, Molina PE
Chronic binge alcohol consumption alters myogenic gene expression and reduces in vitro myogenic differentiation potential of myoblasts from rhesus macaques.
Am J Physiol Regul Integr Comp Physiol. 2014 Jun 1;306(11):R837-44. doi:10.1152/ajpregu.00502.2013. Epub 2014 Mar 26. 2014.

Smith AJ, Wietgrefe SW, Shang L, Reilly CS, Southern PJ, Perkey KE, Duan L, Kohler H, Muller S, Robinson J, Carlis JV, Li Q, Johnson RP, Haase AT
Live simian immunodeficiency virus vaccine correlate of protection: immunecomplex-inhibitory Fc receptor interactions that reduce target cell availability.
J Immunol. 2014 Sep 15;193(6):3126-33. doi: 10.4049/jimmunol.1400822. Epub 2014Aug 20. 2014.

Vaccari M, Fenizia C, Ma ZM, Hryniewicz A, Boasso A, Doster MN, Miller CJ, Lindegardh N, Tarning J, Landay AL, Shearer GM, Franchini G
Transient increase of interferon-stimulated genes and no clinical benefit bychloroquine treatment during acute simian immunodeficiency virus infection of macaques.
AIDS Res Hum Retroviruses. 2014 Apr;30(4):355-62. doi: 10.1089/AID.2013.0218.Epub 2013 Dec 24. 2014.

Vallender EJ
Bringing non-human primate research into the post-genomic era: how monkeys areteaching us about elite controllers of HIV/AIDS.
Genome Biol. 2014 Nov 7;15(11):507. doi: 10.1186/s13059-014-0507-y. 2014.

Van Rompay KK, Hunter Z, Jayashankar K, Peabody J, Montefiori D, LaBranche CC, Keele BF, Jensen K, Abel K, Chackerian B
A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.
J Virol. 2014 Feb;88(4):2011-24. doi: 10.1128/JVI.02447-13. Epub 2013 Dec 4. 2014.

Verhoeven D, George MD, Hu W, Dang AT, Smit-McBride Z, Reay E, Macal M, Fenton A, Sankaran-Walters S, Dandekar S
Enhanced innate antiviral gene expression, IFN-alpha, and cytolytic responses arepredictive of mucosal immune recovery during simian immunodeficiency virus infection.
J Immunol. 2014 Apr 1;192(7):3308-18. doi: 10.4049/jimmunol.1302415. Epub 2014Mar 7. 2014.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW
Variation of human immunodeficiency virus type-1 reverse transcriptase within thesimian immunodeficiency virus genome of RT-SHIV.
PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection2014. 2014.

Westmoreland SV, Converse AP, Hrecka K, Hurley M, Knight H, Piatak M, Lifson J, Mansfield KG, Skowronski J, Desrosiers RC
SIV vpx is essential for macrophage infection but not for development of AIDS.
PLoS One. 2014 Jan 21;9(1):e84463. doi: 10.1371/journal.pone.0084463. eCollection2014. 2014.

Zhou M, Ruprecht RM
Are anti-HIV IgAs good guys or bad guys?
Retrovirology. 2014 Dec 14;11:109. doi: 10.1186/s12977-014-0109-5. 2014.

Zhuang K, Leda AR, Tsai L, Knight H, Harbison C, Gettie A, Blanchard J, Westmoreland S, Cheng-Mayer C
Emergence of CD4 independence envelopes and astrocyte infection in R5simian-human immunodeficiency virus model of encephalitis.
J Virol. 2014 Aug;88(15):8407-20. doi: 10.1128/JVI.01237-14. Epub 2014 May 14. 2014.

2013

Bachler BC, Humbert M, Lakhashe SK, Rasmussen RA, Ruprecht RM
Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia.
Retrovirology. 2013 Jun 21;10:63. doi: 10.1186/1742-4690-10-63. 2013.

Bachler BC, Humbert M, Palikuqi B, Siddappa NB, Lakhashe SK, Rasmussen RA, Ruprecht RM
Novel biopanning strategy to identify epitopes associated with vaccineprotection.
J Virol. 2013 Apr;87(8):4403-16. doi: 10.1128/JVI.02888-12. Epub 2013 Feb 6. 2013.

Barouch DH, Stephenson KE, Borducchi EN, Smith K, Stanley K, McNally AG, Liu J, Abbink P, Maxfield LF, Seaman MS, Dugast AS, Alter G, Ferguson M, Li W, Earl PL, Moss B, Giorgi EE, Szinger JJ, Eller LA, Billings EA, Rao M, Tovanabutra S, Sanders-Buell E, Weijtens M, Pau MG, Schuitemaker H, Robb ML, Kim JH, Korber BT, Michael NL
Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIVchallenges in rhesus monkeys.
Cell. 2013 Oct 24;155(3):531-9. doi: 10.1016/j.cell.2013.09.061. Epub 2013 Oct24. 2013.

Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, Smith JY, Blackmore S, Sanisetty S, Perry JR, Beck M, Lewis MG, Rinaldi W, Chakraborty AK, Poignard P, Nussenzweig MC, Burton DR
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.
Nature. 2013 Nov 14;503(7475):224-8. doi: 10.1038/nature12744. Epub 2013 Oct 30. 2013.

Bosinger SE, Jochems SP, Folkner KA, Hayes TL, Klatt NR, Silvestri G
Transcriptional profiling of experimental CD8(+) lymphocyte depletion in rhesusmacaques infected with simian immunodeficiency virus SIVmac239.
J Virol. 2013 Jan;87(1):433-43. doi: 10.1128/JVI.01746-12. Epub 2012 Oct 24. 2013.

Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M Jr, Lifson JD, Keele BF, Hoxie JA, Lackner AA
Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiencyvirus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.
J Virol. 2013 Feb;87(3):1528-43. doi: 10.1128/JVI.01928-12. Epub 2012 Nov 14. 2013.

Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA
A single amino acid mutation in the envelope cytoplasmic tail restores theability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells.
J Virol. 2013 Dec;87(23):13048-52. doi: 10.1128/JVI.02126-13. Epub 2013 Sep 11. 2013.

Burdo TH, Lackner A, Williams KC
Monocyte/macrophages and their role in HIV neuropathogenesis.
Immunol Rev. 2013 Jul;254(1):102-13. doi: 10.1111/imr.12068. 2013.

Byrareddy SN, Ayash-Rashkovsky M, Kramer VG, Lee SJ, Correll M, Novembre FJ, Villinger F, Johnson WE, von Gegerfelt A, Felber BK, Ruprecht RM
Live attenuated Rev-independent Nef SIV enhances acquisition of heterologousSIVsmE660 in acutely vaccinated rhesus macaques.
PLoS One. 2013 Sep 30;8(9):e75556. doi: 10.1371/journal.pone.0075556. eCollection2013. 2013.

Cain BT, Pham NH, Budde ML, Greene JM, Weinfurter JT, Scarlotta M, Harris M, Chin E, O'Connor SL, Friedrich TC, O'Connor DH
T cell response specificity and magnitude against SIVmac239 are not concordant inmajor histocompatibility complex-matched animals.
Retrovirology. 2013 Oct 24;10:116. doi: 10.1186/1742-4690-10-116. 2013.

Cervasi B, Carnathan DG, Sheehan KM, Micci L, Paiardini M, Kurupati R, Tuyishime S, Zhou XY, Else JG, Ratcliffe SJ, Ertl HC, Silvestri G
Immunological and virological analyses of rhesus macaques immunized withchimpanzee adenoviruses expressing the simian immunodeficiency virus Gag/Tat fusion protein and challenged intrarectally with repeated low doses of SIVmac.
J Virol. 2013 Sep;87(17):9420-30. doi: 10.1128/JVI.01456-13. Epub 2013 Jun 26. 2013.

Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF
T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infectedhumans and simian immunodeficiency virus-infected Indian rhesus macaques.
J Virol. 2013 Jun;87(11):6073-80. doi: 10.1128/JVI.00579-12. Epub 2013 Mar 27. 2013.

Cummings Macri S, Knight HL, Miller AD
Mesenchymoproliferative enteropathy associated with dual simian polyomavirus and rhesus cytomegalovirus infection in a simian immunodeficiency virus-infected rhesus macaque (Macaca mulatta).
Vet Pathol. 2013 Jul;50(4):715-21. doi: 10.1177/0300985812463405. Epub 2012 Oct9. 2013.

Del Prete GQ, Scarlotta M, Newman L, Reid C, Parodi LM, Roser JD, Oswald K, Marx PA, Miller CJ, Desrosiers RC, Barouch DH, Pal R, Piatak M Jr, Chertova E, Giavedoni LD, O'Connor DH, Lifson JD, Keele BF
Comparative characterization of transfection- and infection-derived simianimmunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
J Virol. 2013 Apr;87(8):4584-95. doi: 10.1128/JVI.03507-12. Epub 2013 Feb 13. 2013.

Fetherston SM, Geer L, Veazey RS, Goldman L, Murphy DJ, Ketas TJ, Klasse PJ, Blois S, La Colla P, Moore JP, Malcolm RK
Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesusmacaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.
J Antimicrob Chemother. 2013 Feb;68(2):394-403. doi: 10.1093/jac/dks415. Epub2012 Oct 28. 2013.

Fraietta JA, Mueller YM, Yang G, Boesteanu AC, Gracias DT, Do DH, Hope JL, Kathuria N, McGettigan SE, Lewis MG, Giavedoni LD, Jacobson JM, Katsikis PD
Type I interferon upregulates Bak and contributes to T cell loss during humanimmunodeficiency virus (HIV) infection.
PLoS Pathog. 2013;9(10):e1003658. doi: 10.1371/journal.ppat.1003658. Epub 2013Oct 10. 2013.

Francella N, Gwyn SE, Yi Y, Li B, Xiao P, Elliott ST, Ortiz AM, Hoxie JA, Paiardini M, Silvestri G, Derdeyn CA, Collman RG
CD4+ T cells support production of simian immunodeficiency virus Env antibodiesthat enforce CD4-dependent entry and shape tropism in vivo.
J Virol. 2013 Sep;87(17):9719-32. doi: 10.1128/JVI.01254-13. Epub 2013 Jul 3. 2013.

Giavedoni LD, Chen HL, Hodara VL, Chu L, Parodi LM, Smith LM, Sexton V, Cappelli D, Sodora DL
Impact of mucosal inflammation on oral simian immunodeficiency virustransmission.
J Virol. 2013 Feb;87(3):1750-8. doi: 10.1128/JVI.02079-12. Epub 2012 Nov 21. 2013.

Gori JL, Beard BC, Williams NP, Ironside C, Swanson D, Scott McIvor R, Kiem HP
In vivo protection of activated Tyr22-dihydrofolate reductase gene-modifiedcanine T lymphocytes from methotrexate.
J Gene Med. 2013 Jun-Jul;15(6-7):233-41. doi: 10.1002/jgm.2713. 2013.

Greene JM, Lhost JJ, Hines PJ, Scarlotta M, Harris M, Burwitz BJ, Budde ML, Dudley DM, Pham N, Cain B, Mac Nair CE, Weiker MK, O'Connor SL, Friedrich TC, O'Connor DH
Adoptive transfer of lymphocytes isolated from simian immunodeficiency virusSIVmac239Deltanef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients.
J Virol. 2013 Jul;87(13):7382-92. doi: 10.1128/JVI.00348-13. Epub 2013 Apr 24. 2013.

Gupta M, Miller CJ, Baker JV, Lazar J, Bogner JR, Calmy A, Soliman EZ, Neaton JD
Biomarkers and electrocardiographic evidence of myocardial ischemia in patientswith human immunodeficiency virus infection.
Am J Cardiol. 2013 Mar 1;111(5):760-4. doi: 10.1016/j.amjcard.2012.11.032. Epub2012 Dec 29. 2013.

Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN
The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1(HIV-1) transcytosis across epithelial cells.
PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013Nov 21. 2013.

Hansen SG, Piatak M Jr, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, Turner JM, Legasse AW, Axthelm MK, Nelson JA, Fruh K, Sacha JB, Estes JD, Keele BF, Edlefsen PT, Lifson JD, Picker LJ
Immune clearance of highly pathogenic SIV infection.
Nature. 2013 Oct 3;502(7469):100-4. doi: 10.1038/nature12519. Epub 2013 Sep 11. 2013.

Hansen SG, Sacha JB, Hughes CM, Ford JC, Burwitz BJ, Scholz I, Gilbride RM, Lewis MS, Gilliam AN, Ventura AB, Malouli D, Xu G, Richards R, Whizin N, Reed JS, Hammond KB, Fischer M, Turner JM, Legasse AW, Axthelm MK, Edlefsen PT, Nelson JA, Lifson JD, Fruh K, Picker LJ
Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms.
Science. 2013 May 24;340(6135):1237874. doi: 10.1126/science.1237874. 2013.

Harbison CE, Ellis ME, Westmoreland SV
Spontaneous cervicovaginal lesions and immune cell infiltrates in nonhumanprimates.
Toxicol Pathol. 2013;41(7):1016-27. doi: 10.1177/0192623313477754. Epub 2013 Feb 20. 2013.

Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, Colgin LM, Axthelm M, Messaoudi I, Sacha JB, Burton DR, Forthal DN, Hessell AJ, Haigwood NL
Neutralizing polyclonal IgG present during acute infection prevents rapid diseaseonset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques.
J Virol. 2013 Oct;87(19):10447-59. doi: 10.1128/JVI.00049-13. Epub 2013 Jul 24. 2013.

Jensen K, Pena MG, Wilson RL, Ranganathan UD, Jacobs WR Jr, Fennelly G, Larsen M, Van Rompay KK, Kozlowski PA, Abel K
A neonatal oral Mycobacterium tuberculosis-SIV prime / intramuscular MVA-SIVboost combination vaccine induces both SIV and Mtb-specific immune responses in infant macaques.
Trials Vaccinol. 2013 Nov 1;2:53-63. doi: 10.1016/j.trivac.2013.09.005. 2013.

Kaliyaperumal S, Dang X, Wuethrich C, Knight HL, Pearson C, MacKey J, Mansfield KG, Koralnik IJ, Westmoreland SV
Frequent infection of neurons by SV40 virus in SIV-infected macaque monkeys with progressive multifocal leukoencephalopathy and meningoencephalitis.
Am J Pathol. 2013 Dec;183(6):1910-1917. doi: 10.1016/j.ajpath.2013.08.007. Epub2013 Oct 1. 2013.

Kenney J, Rodriguez A, Kizima L, Seidor S, Menon R, Jean-Pierre N, Pugach P, Levendosky K, Derby N, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Paglini G, Zydowsky TM, Robbiani M, Fernandez Romero JA
A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safeand effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.
Antimicrob Agents Chemother. 2013 Aug;57(8):4001-9. doi: 10.1128/AAC.00796-13.Epub 2013 Jun 10. 2013.

Kenway-Lynch CS, Das A, Pan D, Lackner AA, Pahar B
Dynamics of cytokine/chemokine responses in intestinal CD4+ and CD8+ T Cellsduring Acute Simian Immunodeficiency Virus Infection.
J Virol. 2013 Nov;87(21):11916-23. doi: 10.1128/JVI.01750-13. Epub 2013 Aug 21. 2013.

Klatt NR, Chomont N, Douek DC, Deeks SG
Immune activation and HIV persistence: implications for curative approaches toHIV infection.
Immunol Rev. 2013 Jul;254(1):326-42. doi: 10.1111/imr.12065. 2013.

Klein K, Veazey RS, Warrier R, Hraber P, Doyle-Meyers LA, Buffa V, Liao HX, Haynes BF, Shaw GM, Shattock RJ
Neutralizing IgG at the portal of infection mediates protection against vaginalsimian/human immunodeficiency virus challenge.
J Virol. 2013 Nov;87(21):11604-16. doi: 10.1128/JVI.01361-13. Epub 2013 Aug 21. 2013.

Kloverpris HN, Payne RP, Sacha JB, Rasaiyaah JT, Chen F, Takiguchi M, Yang OO, Towers GJ, Goulder P, Prado JG
Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells.
J Virol. 2013 Mar;87(5):2628-38. doi: 10.1128/JVI.02131-12. Epub 2012 Dec 19. 2013.

Kurupati R, Tuyishime S, Kossenkov AV, Sazanovich M, Haut LH, Lasaro MO, Ratcliffe SJ, Bosinger SE, Carnathan DG, Lewis M, Showe LC, Silvestri G, Ertl HC
Correlates of relative resistance against low-dose rectal simian immunodeficiencyvirus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques.
J Leukoc Biol. 2013 Mar;93(3):437-48. doi: 10.1189/jlb.0612287. Epub 2012 Dec 27. 2013.

Lauck M, Switzer WM, Sibley SD, Hyeroba D, Tumukunde A, Weny G, Taylor B, Shankar A, Ting N, Chapman CA, Friedrich TC, Goldberg TL, O'Connor DH
Discovery and full genome characterization of two highly divergent simianimmunodeficiency viruses infecting black-and-white colobus monkeys (Colobus guereza) in Kibale National Park, Uganda.
Retrovirology. 2013 Oct 21;10:107. doi: 10.1186/1742-4690-10-107. 2013.

Letko M, Silvestri G, Hahn BH, Bibollet-Ruche F, Gokcumen O, Simon V, Ooms M
Vif proteins from diverse primate lentiviral lineages use the same binding sitein APOBEC3G.
J Virol. 2013 Nov;87(21):11861-71. doi: 10.1128/JVI.01944-13. Epub 2013 Aug 28. 2013.

Li H, Gillis J, Johnson RP, Reeves RK
Multi-functional plasmacytoid dendritic cells redistribute to gut tissues during simian immunodeficiency virus infection.
Immunology. 2013 Oct;140(2):244-9. doi: 10.1111/imm.12132. 2013.

Ling B, Rogers L, Johnson AM, Piatak M, Lifson J, Veazey RS
Effect of combination antiretroviral therapy on Chinese rhesus macaques of simianimmunodeficiency virus infection.
AIDS Res Hum Retroviruses. 2013 Nov;29(11):1465-74. doi: 10.1089/AID.2012.0378.Epub 2013 Mar 8. 2013.

Malcolm RK, Forbes CJ, Geer L, Veazey RS, Goldman L, Klasse PJ, Moore JP
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesusmacaques.
J Antimicrob Chemother. 2013 Mar;68(3):678-83. doi: 10.1093/jac/dks422. Epub 2012Oct 30. 2013.

Malherbe DC, Sanders RW, van Gils MJ, Park B, Gomes MM, Schuitemaker H, Barnett S, Haigwood NL
HIV-1 envelope glycoprotein resistance to monoclonal antibody 2G12 issubject-specific and context-dependent in macaques and humans.
PLoS One. 2013 Sep 9;8(9):e75277. doi: 10.1371/journal.pone.0075277. eCollection 2013. 2013.

Manrique J, Piatak M, Lauer W, Johnson W, Mansfield K, Lifson J, Desrosiers R
Influence of mismatch of Env sequences on vaccine protection by live attenuatedsimian immunodeficiency virus.
J Virol. 2013 Jul;87(13):7246-54. doi: 10.1128/JVI.00798-13. Epub 2013 May 1. 2013.

Marker DF, Tremblay ME, Puccini JM, Barbieri J, Gantz Marker MA, Loweth CJ, Muly EC, Lu SM, Goodfellow VS, Dewhurst S, Gelbard HA
The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 isneuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
J Neurosci. 2013 Jun 12;33(24):9998-10010. doi: 10.1523/JNEUROSCI.0598-13.2013. 2013.

Martins MA, Bonaldo MC, Rudersdorf RA, Piaskowski SM, Rakasz EG, Weisgrau KL, Furlott JR, Eernisse CM, Veloso de Santana MG, Hidalgo B, Friedrich TC, Chiuchiolo MJ, Parks CL, Wilson NA, Allison DB, Galler R, Watkins DI
Immunogenicity of seven new recombinant yellow fever viruses 17D expressingfragments of SIVmac239 Gag, Nef, and Vif in Indian rhesus macaques.
PLoS One. 2013;8(1):e54434. doi: 10.1371/journal.pone.0054434. Epub 2013 Jan 15. 2013.

McLinden JH, Stapleton JT, Klinzman D, Murthy KK, Chang Q, Kaufman TM, Bhattarai N, Xiang J
Chimpanzee GB virus C and GB virus A E2 envelope glycoproteins contain a peptide motif that inhibits human immunodeficiency virus type 1 replication in human CD4(+) T-cells.
J Gen Virol. 2013 Apr;94(Pt 4):774-82. doi: 10.1099/vir.0.047126-0. Epub 2013 Jan3. 2013.

Mothe BR, Southwood S, Sidney J, English AM, Wriston A, Hoof I, Shabanowitz J, Hunt DF, Sette A
Peptide-binding motifs associated with MHC molecules common in Chinese rhesusmacaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles.
Immunogenetics. 2013 May;65(5):371-86. doi: 10.1007/s00251-013-0686-9. Epub 2013 Feb 17. 2013.

Mumbauer A, Gettie A, Blanchard J, Cheng-Mayer C
Efficient mucosal transmissibility but limited pathogenicity of R5 SHIV SF162P3N in Chinese-origin rhesus macaques.
J Acquir Immune Defic Syndr. 2013 Apr 15;62(5):496-504. doi:10.1097/QAI.0b013e31827f1c11. 2013.

Navara CS, Hornecker J, Grow D, Chaudhari S, Hornsby PJ, Ichida JK, Eggan K, McCarrey JR
Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies.
Cell Reprogram. 2013 Dec;15(6):495-502. doi: 10.1089/cell.2012.0093. Epub 2013Nov 4. 2013.

Nelson S, Happel KI, Zhang P, Myers L, Dufour JP, Bagby GJ
Effect of bacterial pneumonia on lung simian immunodeficiency virus (SIV)replication in alcohol consuming SIV-infected rhesus macaques.
Alcohol Clin Exp Res. 2013 Jun;37(6):969-77. doi: 10.1111/acer.12070. Epub 2013Feb 15. 2013.

Ocon S, Murphy C, Dang AT, Sankaran-Walters S, Li CS, Tarara R, Borujerdpur N, Dandekar S, Paster BJ, George MD
Transcription profiling reveals potential mechanisms of dysbiosis in the oralmicrobiome of rhesus macaques with chronic untreated SIV infection.
PLoS One. 2013 Nov 29;8(11):e80863. doi: 10.1371/journal.pone.0080863.eCollection 2013. 2013.

Okoye AA, Picker LJ
CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure.
Immunol Rev. 2013 Jul;254(1):54-64. doi: 10.1111/imr.12066. 2013.

Pahar B, Amedee AM, Thomas J, Dufour JP, Zhang P, Nelson S, Veazey RS, Bagby GJ
Effects of alcohol consumption on antigen-specific cellular and humoral immuneresponses to SIV in rhesus macaques.
J Acquir Immune Defic Syndr. 2013 Dec 1;64(4):332-41. doi:10.1097/QAI.0b013e31829f6dca. 2013.

Paiardini M, Muller-Trutwin M
HIV-associated chronic immune activation.
Immunol Rev. 2013 Jul;254(1):78-101. doi: 10.1111/imr.12079. 2013.

Palermo RE, Fuller DH
'Omics investigations of HIV and SIV pathogenesis and innate immunity.
Curr Top Microbiol Immunol. 2013;363:87-116. doi: 10.1007/82_2012_255. 2013.

Parks CL, Picker LJ, King CR
Development of replication-competent viral vectors for HIV vaccine delivery.
Curr Opin HIV AIDS. 2013 Sep;8(5):402-11. doi: 10.1097/COH.0b013e328363d389. 2013.

Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, Alicea C, von Gegerfelt A, Huang W, Guan Y, Keele BF, Bess JW Jr, Piatak M Jr, Lifson JD, Williams WT, Shen X, Tomaras GD, Amara RR, Robinson HL, Johnson W, Broderick KE, Sardesai NY, Venzon DJ, Hirsch VM, Felber BK, Pavlakis GN
DNA and virus particle vaccination protects against acquisition and conferscontrol of viremia upon heterologous simian immunodeficiency virus challenge.
Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2975-80. doi:10.1073/pnas.1215393110. Epub 2013 Jan 28. 2013.

Peterson CW, Younan P, Polacino PS, Maurice NJ, Miller HW, Prlic M, Jerome KR, Woolfrey AE, Hu SL, Kiem HP
Robust suppression of env-SHIV viremia in Macaca nemestrina by 3-drug ART isindependent of timing of initiation during chronic infection.
J Med Primatol. 2013 Oct;42(5):237-46. doi: 10.1111/jmp.12060. 2013.

Postler TS, Desrosiers RC
The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.
J Virol. 2013 Jan;87(1):2-15. doi: 10.1128/JVI.02053-12. Epub 2012 Oct 17. 2013.

Prentice HA, Porter TR, Price MA, Cormier E, He D, Farmer PK, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, Hunter E, Kaslow RA, Gilmour J, Tang J
HLA-B*57 versus HLA-B*81 in HIV-1 infection: slow and steady wins the race?
J Virol. 2013 Apr;87(7):4043-51. doi: 10.1128/JVI.03302-12. Epub 2013 Jan 30. 2013.

Qin A, Cai W, Pan T, Wu K, Yang Q, Wang N, Liu Y, Yan D, Hu F, Guo P, Chen X, Chen L, Zhang H, Tang X, Zhou J
Expansion of monocytic myeloid-derived suppressor cells dampens T cell functionin HIV-1-seropositive individuals.
J Virol. 2013 Feb;87(3):1477-90. doi: 10.1128/JVI.01759-12. Epub 2012 Nov 14. 2013.

Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT
Tetherin upregulation in simian immunodeficiency virus-infected macaques.
J Virol. 2013 Dec;87(24):13917-21. doi: 10.1128/JVI.01757-13. Epub 2013 Oct 9. 2013.

Ramesh G, MacLean AG, Philipp MT
Cytokines and chemokines at the crossroads of neuroinflammation,neurodegeneration, and neuropathic pain.
Mediators Inflamm. 2013;2013:480739. doi: 10.1155/2013/480739. Epub 2013 Aug 12. 2013.

Ren W, Mumbauer A, Gettie A, Seaman MS, Russell-Lodrigue K, Blanchard J, Westmoreland S, Cheng-Mayer C
Generation of lineage-related, mucosally transmissible subtype C R5 simian-human immunodeficiency viruses capable of AIDS development, induction of neurological disease, and coreceptor switching in rhesus macaques.
J Virol. 2013 Jun;87(11):6137-49. doi: 10.1128/JVI.00178-13. Epub 2013 Mar 20. 2013.

Ren W, Mumbauer A, Zhuang K, Harbison C, Knight H, Westmoreland S, Gettie A, Blanchard J, Cheng-Mayer C
Mucosal transmissibility, disease induction and coreceptor switching of R5SHIVSF162P3N molecular clones in rhesus macaques.
Retrovirology. 2013 Jan 31;10:9. doi: 10.1186/1742-4690-10-9. 2013.

Tabb B, Morcock DR, Trubey CM, Quinones OA, Hao XP, Smedley J, Macallister R, Piatak M Jr, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD
Reduced inflammation and lymphoid tissue immunopathology in rhesus macaquesreceiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.
J Infect Dis. 2013 Mar 15;207(6):880-92. doi: 10.1093/infdis/jis643. Epub 2012Oct 19. 2013.

Trott KA, Richardson A, Hudgens MA, Abel K
Immune activation and regulation in simian immunodeficiency virus-Plasmodiumfragile-coinfected rhesus macaques.
J Virol. 2013 Sep;87(17):9523-37. doi: 10.1128/JVI.00861-13. Epub 2013 Jun 19. 2013.

Tso FY, Abrahamyan L, Hu SL, Ruprecht RM, Wood C
Variations in the Biological Functions of HIV-1 Clade C Envelope in aSHIV-Infected Rhesus Macaque during Disease Progression.
PLoS One. 2013 Jun 26;8(6):e66973. doi: 10.1371/journal.pone.0066973. Print 2013. 2013.

Vaccari M, Keele BF, Bosinger SE, Doster MN, Ma ZM, Pollara J, Hryniewicz A, Ferrari G, Guan Y, Forthal DN, Venzon D, Fenizia C, Morgan T, Montefiori D, Lifson JD, Miller CJ, Silvestri G, Rosati M, Felber BK, Pavlakis GN, Tartaglia J, Franchini G
Protection afforded by an HIV vaccine candidate in macaques depends on the doseof SIVmac251 at challenge exposure.
J Virol. 2013 Mar;87(6):3538-48. doi: 10.1128/JVI.02863-12. Epub 2013 Jan 16. 2013.

Walsh AD, Bimber BN, Das A, Piaskowski SM, Rakasz EG, Bean AT, Mudd PA, Ericsen AJ, Wilson NA, Hughes AL, O'Connor DH, Maness NJ
Acute phase CD8+ T lymphocytes against alternate reading frame epitopes selectfor rapid viral escape during SIV infection.
PLoS One. 2013 May 6;8(5):e61383. doi: 10.1371/journal.pone.0061383. Print 2013. 2013.

Wang X, Xu H, Pahar B, Lackner AA, Veazey RS
Divergent kinetics of proliferating T cell subsets in simian immunodeficiencyvirus (SIV) infection: SIV eliminates the 'first responder' CD4+ T cells in primary infection.
J Virol. 2013 Jun;87(12):7032-8. doi: 10.1128/JVI.00027-13. Epub 2013 Apr 17. 2013.

Weiss LM, Cushion MT, Didier E, Xiao L, Marciano-Cabral F, Sinai AP, Matos O, Calderon EJ, Kaneshiro ES
The 12th International Workshops on Opportunistic Protists (IWOP-12).
J Eukaryot Microbiol. 2013 May-Jun;60(3):298-308. doi: 10.1111/jeu.12034. Epub2013 Apr 5. 2013.

Wood LF, Chahroudi A, Chen HL, Jaspan HB, Sodora DL
The oral mucosa immune environment and oral transmission of HIV/SIV.
Immunol Rev. 2013 Jul;254(1):34-53. doi: 10.1111/imr.12078. 2013.

Xu H, Wang X, Veazey RS
Mucosal immunology of HIV infection.
Immunol Rev. 2013 Jul;254(1):10-33. doi: 10.1111/imr.12072. 2013.

Younan PM, Polacino P, Kowalski JP, Peterson CW, Maurice NJ, Williams NP, Ho O, Trobridge GD, Von Laer D, Prlic M, Beard BC, DeRosa S, Hu SL, Kiem HP
Positive selection of mC46-expressing CD4+ T cells and maintenance of virusspecific immunity in a primate AIDS model.
Blood. 2013 Jul 11;122(2):179-87. doi: 10.1182/blood-2013-01-482224. Epub 2013May 29. 2013.

Zhang X, Li C
Quantitative MRI Measures in SIV-Infected Macaque Brains.
J Clin Cell Immunol. 2013;Suppl 7. doi: 10.4172/2155-9899.S7-005. 2013.

Zhou Y, Bao R, Haigwood NL, Persidsky Y, Ho WZ
SIV infection of rhesus macaques of Chinese origin: a suitable model for HIVinfection in humans.
Retrovirology. 2013 Aug 15;10:89. doi: 10.1186/1742-4690-10-89. 2013.

2012

Acevedo O, Ambrose Z, Flaherty PT, Aamer H, Jain P, Sambasivarao SV
Identification of HIV inhibitors guided by free energy perturbation calculations.
Curr Pharm Des. 2012;18(9):1199-216. doi: 10.2174/138161212799436421. 2012.

Ahsan MH, Gill AF, Lackner AA, Veazey RS
Acute and chronic T cell dynamics in the livers of simian immunodeficiencyvirus-infected macaques.
J Virol. 2012 May;86(9):5244-52. doi: 10.1128/JVI.07080-11. Epub 2012 Feb 29. 2012.

Alpert MD, Harvey JD, Lauer WA, Reeves RK, Piatak M Jr, Carville A, Mansfield KG, Lifson JD, Li W, Desrosiers RC, Johnson RP, Evans DT
ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
PLoS Pathog. 2012;8(8):e1002890. doi: 10.1371/journal.ppat.1002890. Epub 2012 Aug23. 2012.

Alpert MD, Heyer LN, Williams DE, Harvey JD, Greenough T, Allhorn M, Evans DT
A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- orSIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.
J Virol. 2012 Nov;86(22):12039-52. doi: 10.1128/JVI.01650-12. Epub 2012 Aug 29. 2012.

Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin Adependence and impairs macrophage infection.
J Virol. 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1. 2012.

Aravantinou M, Singer R, Derby N, Calenda G, Mawson P, Abraham CJ, Menon R, Seidor S, Goldman D, Kenney J, Villegas G, Gettie A, Blanchard J, Lifson JD, Piatak M Jr, Fernandez-Romero JA, Zydowsky TM, Teleshova N, Robbiani M
The nonnucleoside reverse transcription inhibitor MIV-160 delivered from anintravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT Infection.
AIDS Res Hum Retroviruses. 2012 Nov;28(11):1467-75. doi: 10.1089/aid.2012.0080.Epub 2012 Aug 27. 2012.

Bailey CC, Miller AD
Ulcerative cheilitis in a rhesus macaque.
Vet Pathol. 2012 Mar;49(2):412-5. doi: 10.1177/0300985811400443. Epub 2011 Mar 7. 2012.

Barouch DH, Klasse PJ, Dufour J, Veazey RS, Moore JP
Macaque studies of vaccine and microbicide combinations for preventing HIV-1sexual transmission.
Proc Natl Acad Sci U S A. 2012 May 29;109(22):8694-8. doi:10.1073/pnas.1203183109. Epub 2012 May 14. 2012.

Barouch DH, Liu J, Li H, Maxfield LF, Abbink P, Lynch DM, Iampietro MJ, SanMiguel A, Seaman MS, Ferrari G, Forthal DN, Ourmanov I, Hirsch VM, Carville A, Mansfield KG, Stablein D, Pau MG, Schuitemaker H, Sadoff JC, Billings EA, Rao M, Robb ML, Kim JH, Marovich MA, Goudsmit J, Michael NL
Vaccine protection against acquisition of neutralization-resistant SIV challengesin rhesus monkeys.
Nature. 2012 Jan 4;482(7383):89-93. doi: 10.1038/nature10766. 2012.

Baum PD, Young JJ, Schmidt D, Zhang Q, Hoh R, Busch M, Martin J, Deeks S, McCune JM
Blood T-cell receptor diversity decreases during the course of HIV infection, butthe potential for a diverse repertoire persists.
Blood. 2012 Apr 12;119(15):3469-77. doi: 10.1182/blood-2011-11-395384. Epub 2012 Feb 27. 2012.

Becker EA, Burns CM, Leon EJ, Rajabojan S, Friedman R, Friedrich TC, O'Connor SL, Hughes AL
Experimental analysis of sources of error in evolutionary studies based onRoche/454 pyrosequencing of viral genomes.
Genome Biol Evol. 2012;4(4):457-65. doi: 10.1093/gbe/evs029. Epub 2012 Mar 20. 2012.

Boliar S, Murphy MK, Tran TC, Carnathan DG, Armstrong WS, Silvestri G, Derdeyn CA
B-lymphocyte dysfunction in chronic HIV-1 infection does not prevent cross-clade neutralization breadth.
J Virol. 2012 Aug;86(15):8031-40. doi: 10.1128/JVI.00771-12. Epub 2012 May 23. 2012.

Bosinger SE, Jacquelin B, Benecke A, Silvestri G, Muller-Trutwin M
Systems biology of natural simian immunodeficiency virus infections.
Curr Opin HIV AIDS. 2012 Jan;7(1):71-8. doi: 10.1097/COH.0b013e32834dde01. 2012.

Braun SE, Taube R, Zhu Q, Wong FE, Murakami A, Kamau E, Dwyer M, Qiu G, Daigle J, Carville A, Johnson RP, Marasco WA
In vivo selection of CD4(+) T cells transduced with a gamma-retroviral vectorexpressing a single-chain intrabody targeting HIV-1 tat.
Hum Gene Ther. 2012 Sep;23(9):917-31. doi: 10.1089/hum.2011.184. 2012.

Brenchley JM, Vinton C, Tabb B, Hao XP, Connick E, Paiardini M, Lifson JD, Silvestri G, Estes JD
Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections.
Blood. 2012 Nov 15;120(20):4172-81. doi: 10.1182/blood-2012-06-437608. Epub 2012 Sep 18. 2012.

Bruce AG, Bielefeldt-Ohmann H, Barcy S, Bakke AM, Lewis P, Tsai CC, Murnane RD, Rose TM
Macaque homologs of EBV and KSHV show uniquely different associations with simianAIDS-related lymphomas.
PLoS Pathog. 2012;8(10):e1002962. doi: 10.1371/journal.ppat.1002962. Epub 2012Oct 4. 2012.

Budde ML, Greene JM, Chin EN, Ericsen AJ, Scarlotta M, Cain BT, Pham NH, Becker EA, Harris M, Weinfurter JT, O'Connor SL, Piatak M Jr, Lifson JD, Gostick E, Price DA, Friedrich TC, O'Connor DH
Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques.
J Virol. 2012 Jul;86(14):7596-604. doi: 10.1128/JVI.00716-12. Epub 2012 May 9. 2012.

Burwitz BJ, Giraldo-Vela JP, Reed J, Newman LP, Bean AT, Nimityongskul FA, Castrovinci PA, Maness NJ, Leon EJ, Rudersdorf R, Sacha JB
CD8+ and CD4+ cytotoxic T cell escape mutations precede breakthrough SIVmac239viremia in an elite controller.
Retrovirology. 2012 Nov 6;9:91. doi: 10.1186/1742-4690-9-91. 2012.

Chahroudi A, Bosinger SE, Vanderford TH, Paiardini M, Silvestri G
Natural SIV hosts: showing AIDS the door.
Science. 2012 Mar 9;335(6073):1188-93. doi: 10.1126/science.1217550. 2012.

Dinh MH, Okocha EA, Koons A, Veazey RS, Hope TJ
Expression of structural proteins in human female and male genital epithelia and implications for sexually transmitted infections.
Biol Reprod. 2012 Feb 9;86(2):32. doi: 10.1095/biolreprod.111.094789. Print 2012 Feb. 2012.

Dyavar Shetty R, Velu V, Titanji K, Bosinger SE, Freeman GJ, Silvestri G, Amara RR
PD-1 blockade during chronic SIV infection reduces hyperimmune activation andmicrobial translocation in rhesus macaques.
J Clin Invest. 2012 May;122(5):1712-6. doi: 10.1172/JCI60612. Epub 2012 Apr 23. 2012.

Elliott ST, Riddick NE, Francella N, Paiardini M, Vanderford TH, Li B, Apetrei C, Sodora DL, Derdeyn CA, Silvestri G, Collman RG
Cloning and analysis of sooty mangabey alternative coreceptors that supportsimian immunodeficiency virus SIVsmm entry independently of CCR5.
J Virol. 2012 Jan;86(2):898-908. doi: 10.1128/JVI.06415-11. Epub 2011 Nov 16. 2012.

Endsley AN, Ho RJ
Elucidation of the time course of adenosine deaminase APOBEC3G and viralinfectivity factor vif in HIV-2(287) -infected infant macaques.
J Med Primatol. 2012 Feb;41(1):52-9. doi: 10.1111/j.1600-0684.2011.00518.x. Epub 2011 Oct 24. 2012.

Endsley AN, Ho RJ
Design and characterization of novel peptide-coated lipid nanoparticles fortargeting anti-HIV drug to CD4 expressing cells.
AAPS J. 2012 Jun;14(2):225-35. doi: 10.1208/s12248-012-9329-6. Epub 2012 Mar 6. 2012.

Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, Coombes N, Mahyari E, Hagen SI, Bae JY, Reyes MD 3rd, Swanson T, Legasse AW, Sylwester A, Hansen SG, Smith AT, Stafova P, Shoemaker R, Li Y, Oswald K, Axthelm MK, McDermott A, Ferrari G, Montefiori DC, Edlefsen PT, Piatak M Jr, Lifson JD, Sekaly RP, Picker LJ
Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.
Nat Med. 2012 Nov;18(11):1673-81. doi: 10.1038/nm.2934. Epub 2012 Sep 9. 2012.

Fukazawa Y
[Protective immune responses against HIV/SIV by live attenuated vaccine innon-human primate models].
Uirusu. 2012;62(2):167-74. 2012.

Genesca M, Ma ZM, Wang Y, Assaf B, Qureshi H, Fritts L, Huang Y, McChesney MB, Miller CJ
Live-attenuated lentivirus immunization modulates innate immunity andinflammation while protecting rhesus macaques from vaginal simian immunodeficiency virus challenge.
J Virol. 2012 Sep;86(17):9188-200. doi: 10.1128/JVI.00532-12. Epub 2012 Jun 13. 2012.

Gordon SN, Kines RC, Kutsyna G, Ma ZM, Hryniewicz A, Roberts JN, Fenizia C, Hidajat R, Brocca-Cofano E, Cuburu N, Buck CB, Bernardo ML, Robert-Guroff M, Miller CJ, Graham BS, Lowy DR, Schiller JT, Franchini G
Targeting the vaginal mucosa with human papillomavirus pseudovirion vaccinesdelivering simian immunodeficiency virus DNA.
J Immunol. 2012 Jan 15;188(2):714-23. doi: 10.4049/jimmunol.1101404. Epub 2011Dec 14. 2012.

Handley SA, Thackray LB, Zhao G, Presti R, Miller AD, Droit L, Abbink P, Maxfield LF, Kambal A, Duan E, Stanley K, Kramer J, Macri SC, Permar SR, Schmitz JE, Mansfield K, Brenchley JM, Veazey RS, Stappenbeck TS, Wang D, Barouch DH, Virgin HW
Pathogenic simian immunodeficiency virus infection is associated with expansionof the enteric virome.
Cell. 2012 Oct 12;151(2):253-66. doi: 10.1016/j.cell.2012.09.024. 2012.

Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM
SIV replication in the infected rhesus macaque is limited by the size of thepreexisting TH17 cell compartment.
Sci Transl Med. 2012 May 30;4(136):136ra69. doi: 10.1126/scitranslmed.3003941. 2012.

Haynes BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, Alam SM, Evans DT, Montefiori DC, Karnasuta C, Sutthent R, Liao HX, DeVico AL, Lewis GK, Williams C, Pinter A, Fong Y, Janes H, DeCamp A, Huang Y, Rao M, Billings E, Karasavvas N, Robb ML, Ngauy V, de Souza MS, Paris R, Ferrari G, Bailer RT, Soderberg KA, Andrews C, Berman PW, Frahm N, De Rosa SC, Alpert MD, Yates NL, Shen X, Koup RA, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Rerks-Ngarm S, Michael NL, Kim JH
Immune-correlates analysis of an HIV-1 vaccine efficacy trial.
N Engl J Med. 2012 Apr 5;366(14):1275-86. doi: 10.1056/NEJMoa1113425. 2012.

Hong JJ, Amancha PK, Rogers K, Ansari AA, Villinger F
Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cellsduring simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape.
J Immunol. 2012 Apr 1;188(7):3247-56. doi: 10.4049/jimmunol.1103138. Epub 2012Mar 2. 2012.

Hughes AL, Becker EA, Lauck M, Karl JA, Braasch AT, O'Connor DH, O'Connor SL
SIV genome-wide pyrosequencing provides a comprehensive and unbiased view ofvariation within and outside CD8 T lymphocyte epitopes.
PLoS One. 2012;7(10):e47818. doi: 10.1371/journal.pone.0047818. Epub 2012 Oct 24. 2012.

Hutnick NA, Myles DJ, Hirao L, Scott VL, Ferraro B, Khan AS, Lewis MG, Miller CJ, Bett AJ, Casimiro D, Sardesai NY, Kim JJ, Shiver J, Weiner DB
An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partialprotection from a high-dose SIVmac251 challenge.
Vaccine. 2012 May 2;30(21):3202-8. doi: 10.1016/j.vaccine.2012.02.069. Epub 2012 Mar 8. 2012.

Jasny E, Geer S, Frank I, Vagenas P, Aravantinou M, Salazar AM, Lifson JD, Piatak M Jr, Gettie A, Blanchard JL, Robbiani M
Characterization of peripheral and mucosal immune responses in rhesus macaques onlong-term tenofovir and emtricitabine combination antiretroviral therapy.
J Acquir Immune Defic Syndr. 2012 Dec 1;61(4):425-35. doi:10.1097/QAI.0b013e318266be53. 2012.

Jensen K, Ranganathan UD, Van Rompay KK, Canfield DR, Khan I, Ravindran R, Luciw PA, Jacobs WR Jr, Fennelly G, Larsen MH, Abel K
A recombinant attenuated Mycobacterium tuberculosis vaccine strain is safe inimmunosuppressed simian immunodeficiency virus-infected infant macaques.
Clin Vaccine Immunol. 2012 Aug;19(8):1170-81. doi: 10.1128/CVI.00184-12. Epub2012 Jun 13. 2012.

Jones BG, Sealy RE, Zhan X, Freiden PJ, Surman SL, Blanchard JL, Hurwitz JL
UV-inactivated vaccinia virus (VV) in a multi-envelope DNA-VV-protein (DVP) HIV-1vaccine protects macaques from lethal challenge with heterologous SHIV.
Vaccine. 2012 May 2;30(21):3188-95. doi: 10.1016/j.vaccine.2012.03.001. Epub 2012Mar 14. 2012.

Kenney J, Singer R, Derby N, Aravantinou M, Abraham CJ, Menon R, Seidor S, Zhang S, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Fernandez-Romero JA, Zydowsky TM, Robbiani M
A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection againstvaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.
AIDS Res Hum Retroviruses. 2012 Nov;28(11):1476-84. doi: 10.1089/aid.2012.0087.Epub 2012 Jul 30. 2012.

Klatt NR, Canary LA, Vanderford TH, Vinton CL, Engram JC, Dunham RM, Cronise HE, Swerczek JM, Lafont BA, Picker LJ, Silvestri G, Brenchley JM
Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtailmacaques.
J Virol. 2012 Jan;86(2):1203-13. doi: 10.1128/JVI.06033-11. Epub 2011 Nov 16. 2012.

Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, Belkaid Y, Lifson JD, Silvestri G, Milner JD, Paiardini M, Haddad EK, Brenchley JM
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated withmucosal damage in SIV infection.
Mucosal Immunol. 2012 Nov;5(6):646-57. doi: 10.1038/mi.2012.38. Epub 2012 May 30. 2012.

Lackner AA, Lederman MM, Rodriguez B
HIV pathogenesis: the host.
Cold Spring Harb Perspect Med. 2012 Sep 1;2(9):a007005. doi:10.1101/cshperspect.a007005. 2012.

Lai L, Kwa SF, Kozlowski PA, Montefiori DC, Nolen TL, Hudgens MG, Johnson WE, Ferrari G, Hirsch VM, Felber BK, Pavlakis GN, Earl PL, Moss B, Amara RR, Robinson HL
SIVmac239 MVA vaccine with and without a DNA prime, similar prevention ofinfection by a repeated dose SIVsmE660 challenge despite different immune responses.
Vaccine. 2012 Feb 21;30(9):1737-45. doi: 10.1016/j.vaccine.2011.12.026. Epub 2011Dec 15. 2012.

Malcolm RK, Veazey RS, Geer L, Lowry D, Fetherston SM, Murphy DJ, Boyd P, Major I, Shattock RJ, Klasse PJ, Doyle LA, Rasmussen KK, Goldman L, Ketas TJ, Moore JP
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal ringsin rhesus macaques.
Antimicrob Agents Chemother. 2012 May;56(5):2251-8. doi: 10.1128/AAC.05810-11.Epub 2012 Feb 13. 2012.

Martinez-Navio JM, Desrosiers RC
Neutralizing capacity of monoclonal antibodies that recognize peptide sequencesunderlying the carbohydrates on gp41 of simian immunodeficiency virus.
J Virol. 2012 Dec;86(23):12484-93. doi: 10.1128/JVI.01959-12. Epub 2012 Sep 19. 2012.

McDonnel SJ, Sparger EE, Luciw PA, Murphy BG
Transcriptional regulation of latent feline immunodeficiency virus in peripheral CD4+ T-lymphocytes.
Viruses. 2012 May;4(5):878-88. doi: 10.3390/v4050878. Epub 2012 May 23. 2012.

McDonnel SJ, Sparger EE, Luciw PA, Murphy BG
Pharmacologic reactivation of latent feline immunodeficiency virus ex vivo inperipheral CD4+ T-lymphocytes.
Virus Res. 2012 Dec;170(1-2):174-9. doi: 10.1016/j.virusres.2012.10.009. Epub2012 Oct 13. 2012.

Mir KD, Bosinger SE, Gasper M, Ho O, Else JG, Brenchley JM, Kelvin DJ, Silvestri G, Hu SL, Sodora DL
Simian immunodeficiency virus-induced alterations in monocyte production of tumornecrosis factor alpha contribute to reduced immune activation in sooty mangabeys.
J Virol. 2012 Jul;86(14):7605-15. doi: 10.1128/JVI.06813-11. Epub 2012 May 2. 2012.

Mirmonsef P, Gilbert D, Veazey RS, Wang J, Kendrick SR, Spear GT
A comparison of lower genital tract glycogen and lactic acid levels in women and macaques: implications for HIV and SIV susceptibility.
AIDS Res Hum Retroviruses. 2012 Jan;28(1):76-81. doi: 10.1089/aid.2011.0071. Epub2011 Jun 28. 2012.

Moldt B, Rakasz EG, Schultz N, Chan-Hui PY, Swiderek K, Weisgrau KL, Piaskowski SM, Bergman Z, Watkins DI, Poignard P, Burton DR
Highly potent HIV-specific antibody neutralization in vitro translates intoeffective protection against mucosal SHIV challenge in vivo.
Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18921-5. doi:10.1073/pnas.1214785109. Epub 2012 Oct 25. 2012.

Moldt B, Shibata-Koyama M, Rakasz EG, Schultz N, Kanda Y, Dunlop DC, Finstad SL, Jin C, Landucci G, Alpert MD, Dugast AS, Parren PW, Nimmerjahn F, Evans DT, Alter G, Forthal DN, Schmitz JE, Iida S, Poignard P, Watkins DI, Hessell AJ, Burton DR
A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhancedFcgammaRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.
J Virol. 2012 Jun;86(11):6189-96. doi: 10.1128/JVI.00491-12. Epub 2012 Mar 28. 2012.

Mudd PA, Martins MA, Ericsen AJ, Tully DC, Power KA, Bean AT, Piaskowski SM, Duan L, Seese A, Gladden AD, Weisgrau KL, Furlott JR, Kim YI, Veloso de Santana MG, Rakasz E, Capuano S 3rd, Wilson NA, Bonaldo MC, Galler R, Allison DB, Piatak M Jr, Haase AT, Lifson JD, Allen TM, Watkins DI
Vaccine-induced CD8+ T cells control AIDS virus replication.
Nature. 2012 Nov 1;491(7422):129-33. doi: 10.1038/nature11443. Epub 2012 Sep 30. 2012.

Murphey-Corb M, Rajakumar P, Michael H, Nyaundi J, Didier PJ, Reeve AB, Mitsuya H, Sarafianos SG, Parniak MA
Response of simian immunodeficiency virus to the novel nucleoside reversetranscriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine in vitro and in vivo.
Antimicrob Agents Chemother. 2012 Sep;56(9):4707-12. doi: 10.1128/AAC.00723-12.Epub 2012 Jun 19. 2012.

Murphy B, Vapniarsky N, Hillman C, Castillo D, McDonnel S, Moore P, Luciw PA, Sparger EE
FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection.
Retrovirology. 2012 Feb 7;9:12. doi: 10.1186/1742-4690-9-12. 2012.

Navare AT, Sova P, Purdy DE, Weiss JM, Wolf-Yadlin A, Korth MJ, Chang ST, Proll SC, Jahan TA, Krasnoselsky AL, Palermo RE, Katze MG
Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an earlyhost response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.
Virology. 2012 Jul 20;429(1):37-46. doi: 10.1016/j.virol.2012.03.026. Epub 2012Apr 26. 2012.

O'Connor SL, Becker EA, Weinfurter JT, Chin EN, Budde ML, Gostick E, Correll M, Gleicher M, Hughes AL, Price DA, Friedrich TC, O'Connor DH
Conditional CD8+ T cell escape during acute simian immunodeficiency virusinfection.
J Virol. 2012 Jan;86(1):605-9. doi: 10.1128/JVI.05511-11. Epub 2011 Oct 19. 2012.

Okoye AA, Rohankhedkar M, Abana C, Pattenn A, Reyes M, Pexton C, Lum R, Sylwester A, Planer SL, Legasse A, Park BS, Piatak M Jr, Lifson JD, Axthelm MK, Picker LJ
Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressivesimian immunodeficiency virus infection.
J Exp Med. 2012 Apr 9;209(4):641-51. doi: 10.1084/jem.20112071. Epub 2012 Mar 26. 2012.

Pahar B, Gray WL, Phelps K, Didier ES, deHaro E, Marx PA, Traina-Dorge VL
Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques.
Virol J. 2012 Aug 13;9:160. doi: 10.1186/1743-422X-9-160. 2012.

Pandrea I, Parrish NF, Raehtz K, Gaufin T, Barbian HJ, Ma D, Kristoff J, Gautam R, Zhong F, Haret-Richter GS, Trichel A, Shaw GM, Hahn BH, Apetrei C
Mucosal simian immunodeficiency virus transmission in African green monkeys:susceptibility to infection is proportional to target cell availability at mucosal sites.
J Virol. 2012 Apr;86(8):4158-68. doi: 10.1128/JVI.07141-11. Epub 2012 Feb 8. 2012.

Poignard P, Moldt B, Maloveste K, Campos N, Olson WC, Rakasz E, Watkins DI, Burton DR
Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibody-like molecule CD4-IgG2.
PLoS One. 2012;7(7):e42209. doi: 10.1371/journal.pone.0042209. Epub 2012 Jul 27. 2012.

Postler TS, Desrosiers RC
The cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-kappaBactivation through TGF-beta-activated kinase 1.
Cell Host Microbe. 2012 Feb 16;11(2):181-93. doi: 10.1016/j.chom.2011.12.005. 2012.

Postler TS, Martinez-Navio JM, Yuste E, Desrosiers RC
Evidence against extracellular exposure of a highly immunogenic region in theC-terminal domain of the simian immunodeficiency virus gp41 transmembrane protein.
J Virol. 2012 Jan;86(2):1145-57. doi: 10.1128/JVI.06463-11. Epub 2011 Nov 9. 2012.

Presicce P, Shaw JM, Miller CJ, Shacklett BL, Chougnet CA
Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaquespromote the induction of regulatory T cells.
AIDS. 2012 Jan 28;26(3):263-73. doi: 10.1097/QAD.0b013e32834ed8df. 2012.

Qureshi H, Ma ZM, Huang Y, Hodge G, Thomas MA, DiPasquale J, DeSilva V, Fritts L, Bett AJ, Casimiro DR, Shiver JW, Robert-Guroff M, Robertson MN, McChesney MB, Gilbert PB, Miller CJ
Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirustype 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaccine.
J Virol. 2012 Feb;86(4):2239-50. doi: 10.1128/JVI.06175-11. Epub 2011 Dec 7. 2012.

Rasmussen RA, Siddappa NB, Lakhashe SK, Watkins J, Villinger F, Ibegbu C, Florese RH, Robert-Guroff M, Montefiori DC, Forthal DN, O'Connor D, Ruprecht RM
High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine andboosted by live-virus exposure: prevention of viremia.
AIDS. 2012 Jan 14;26(2):149-55. doi: 10.1097/QAD.0b013e32834d3c4f. 2012.

Reeves RK, Evans TI, Gillis J, Wong FE, Kang G, Li Q, Johnson RP
SIV infection induces accumulation of plasmacytoid dendritic cells in the gutmucosa.
J Infect Dis. 2012 Nov;206(9):1462-8. doi: 10.1093/infdis/jis408. Epub 2012 Jun18. 2012.

Renner NA, Redmann RK, Moroney-Rasmussen T, Sansing HA, Aye PP, Didier PJ, Lackner AA, Maclean AG
S100beta as a novel and accessible indicator for the presence of monocyte-driven encephalitis in AIDS.
Neuropathol Appl Neurobiol. 2012 Apr;38(2):162-74. doi:10.1111/j.1365-2990.2011.01200.x. 2012.

Renner NA, Sansing HA, Morici LA, Inglis FM, Lackner AA, MacLean AG
Microglia activation by SIV-infected macrophages: alterations in morphology andcytokine secretion.
J Neurovirol. 2012 Jun;18(3):213-21. doi: 10.1007/s13365-012-0100-7. Epub 2012Apr 26. 2012.

Reynolds MR, Weiler AM, Piaskowski SM, Piatak M Jr, Robertson HT, Allison DB, Bett AJ, Casimiro DR, Shiver JW, Wilson NA, Lifson JD, Koff WC, Watkins DI
A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge.
Vaccine. 2012 Jun 22;30(30):4465-75. doi: 10.1016/j.vaccine.2012.04.082. Epub2012 May 6. 2012.

Rothaeusler K, Ma ZM, Qureshi H, Carroll TD, Rourke T, McChesney MB, Miller CJ
Antiviral antibodies and T cells are present in the foreskin of simianimmunodeficiency virus-infected rhesus macaques.
J Virol. 2012 Jul;86(13):7098-106. doi: 10.1128/JVI.00410-12. Epub 2012 Apr 24. 2012.

Rout N, Greene J, Yue S, O'Connor D, Johnson RP, Else JG, Exley MA, Kaur A
Loss of effector and anti-inflammatory natural killer T lymphocyte function inpathogenic simian immunodeficiency virus infection.
PLoS Pathog. 2012 Sep;8(9):e1002928. doi: 10.1371/journal.ppat.1002928. Epub 2012Sep 20. 2012.

Schell JB, Bahl K, Rose NF, Buonocore L, Hunter M, Marx PA, LaBranche CC, Montefiori DC, Rose JK
Viral vectored granulocyte-macrophage colony stimulating factor inhibits vaccine protection in an SIV challenge model: protection correlates with neutralizing antibody.
Vaccine. 2012 Jun 13;30(28):4233-9. doi: 10.1016/j.vaccine.2012.04.046. Epub 2012Apr 23. 2012.

Schmitz JE, Ma ZM, Hagan EA, Wilks AB, Furr KL, Linde CH, Zahn RC, Brenchley JM, Miller CJ, Permar SR
Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source ofcell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys.
J Virol. 2012 Oct;86(20):11380-5. doi: 10.1128/JVI.01556-12. Epub 2012 Aug 15. 2012.

Serra-Moreno R, Evans DT
Adaptation of human and simian immunodeficiency viruses for resistance totetherin/BST-2.
Curr HIV Res. 2012 Jun;10(4):277-82. 2012.

Shakirzyanova M, Tsai L, Ren W, Gettie A, Blanchard J, Cheng-Mayer C
Pathogenic consequences of vaginal infection with CCR5-tropic simian-humanimmunodeficiency virus SHIVSF162P3N.
J Virol. 2012 Sep;86(17):9432-42. doi: 10.1128/JVI.00852-12. Epub 2012 Jun 27. 2012.

Singer R, Mawson P, Derby N, Rodriguez A, Kizima L, Menon R, Goldman D, Kenney J, Aravantinou M, Seidor S, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Fernandez-Romero JA, Robbiani M, Zydowsky TM
An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission inmacaques.
Sci Transl Med. 2012 Sep 5;4(150):150ra123. doi: 10.1126/scitranslmed.3003936. 2012.

Spear G, Rothaeulser K, Fritts L, Gillevet PM, Miller CJ
In captive rhesus macaques, cervicovaginal inflammation is common but notassociated with the stable polymicrobial microbiome.
PLoS One. 2012;7(12):e52992. doi: 10.1371/journal.pone.0052992. Epub 2012 Dec 28. 2012.

Strickland SL, Gray RR, Lamers SL, Burdo TH, Huenink E, Nolan DJ, Nowlin B, Alvarez X, Midkiff CC, Goodenow MM, Williams K, Salemi M
Efficient transmission and persistence of low-frequency SIVmac251 variants inCD8-depleted rhesus macaques with different neuropathology.
J Gen Virol. 2012 May;93(Pt 5):925-38. doi: 10.1099/vir.0.039586-0. Epub 2012 Feb1. 2012.

Sugimoto C, Nakamura S, Hagen SI, Tsunetsugu-Yokota Y, Villinger F, Ansari AA, Suzuki Y, Yamamoto N, Nagai Y, Picker LJ, Mori K
Glycosylation of simian immunodeficiency virus influences immune-tissue targetingduring primary infection, leading to immunodeficiency or viral control.
J Virol. 2012 Sep;86(17):9323-36. doi: 10.1128/JVI.00948-12. Epub 2012 Jun 20. 2012.

Ta LH, Hansen LM, Sause WE, Shiva O, Millstein A, Ottemann KM, Castillo AR, Solnick JV
Conserved transcriptional unit organization of the cag pathogenicity island amongHelicobacter pylori strains.
Front Cell Infect Microbiol. 2012 Apr 20;2:46. doi: 10.3389/fcimb.2012.00046.eCollection 2012. 2012.

Tarantal AF, Giannoni F, Lee CC, Wherley J, Sumiyoshi T, Martinez M, Kahl CA, Elashoff D, Louie SG, Kohn DB
Nonmyeloablative conditioning regimen to increase engraftment of gene-modifiedhematopoietic stem cells in young rhesus monkeys.
Mol Ther. 2012 May;20(5):1033-45. doi: 10.1038/mt.2011.312. Epub 2012 Jan 31. 2012.

Tso FY, Tully DC, Gonzalez S, Quince C, Ho O, Polacino P, Ruprecht RM, Hu SL, Wood C
Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaquesduring disease progression analyzed by ultra-deep pyrosequencing.
PLoS One. 2012;7(3):e32827. doi: 10.1371/journal.pone.0032827. Epub 2012 Mar 12. 2012.

Uchida N, Chen K, Dohse M, Hansen KD, Dean J, Buser JR, Riddle A, Beardsley DJ, Wan Y, Gong X, Nguyen T, Cummings BJ, Anderson AJ, Tamaki SJ, Tsukamoto A, Weissman IL, Matsumoto SG, Sherman LS, Kroenke CD, Back SA
Human neural stem cells induce functional myelination in mice with severedysmyelination.
Sci Transl Med. 2012 Oct 10;4(155):155ra136. doi: 10.1126/scitranslmed.3004371. 2012.

Van Rompay KK, Babusis D, Abbott Z, Geng Y, Jayashankar K, Johnson JA, Lipscomb J, Heneine W, Abel K, Ray AS
Compared to subcutaneous tenofovir, oral tenofovir disoproxyl fumarateadministration preferentially concentrates the drug into gut-associated lymphoid cells in simian immunodeficiency virus-infected macaques.
Antimicrob Agents Chemother. 2012 Sep;56(9):4980-4. doi: 10.1128/AAC.01095-12.Epub 2012 Jul 9. 2012.

Van Rompay KK, Trott KA, Jayashankar K, Geng Y, LaBranche CC, Johnson JA, Landucci G, Lipscomb J, Tarara RP, Canfield DR, Heneine W, Forthal DN, Montefiori D, Abel K
Prolonged tenofovir treatment of macaques infected with K65R reversetranscriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
Retrovirology. 2012 Jul 17;9:57. doi: 10.1186/1742-4690-9-57. 2012.

Van Rompay KK
The use of nonhuman primate models of HIV infection for the evaluation ofantiviral strategies.
AIDS Res Hum Retroviruses. 2012 Jan;28(1):16-35. doi: 10.1089/aid.2011.0234. Epub2011 Oct 19. 2012.

Vojnov L, Martins MA, Bean AT, Veloso de Santana MG, Sacha JB, Wilson NA, Bonaldo MC, Galler R, Stevenson M, Watkins DI
The majority of freshly sorted simian immunodeficiency virus (SIV)-specificCD8(+) T cells cannot suppress viral replication in SIV-infected macrophages.
J Virol. 2012 Apr;86(8):4682-7. doi: 10.1128/JVI.06324-11. Epub 2012 Feb 8. 2012.

Wunderlich S, Haase A, Merkert S, Beier J, Schwanke K, Schambach A, Glage S, Gohring G, Curnow EC, Martin U
Induction of pluripotent stem cells from a cynomolgus monkey using apolycistronic simian immunodeficiency virus-based vector, differentiation toward functional cardiomyocytes, and generation of stably expressing reporter lines.
Cell Reprogram. 2012 Dec;14(6):471-84. doi: 10.1089/cell.2012.0041. 2012.

Xu H, Wang X, Liu DX, Moroney-Rasmussen T, Lackner AA, Veazey RS
IL-17-producing innate lymphoid cells are restricted to mucosal tissues and aredepleted in SIV-infected macaques.
Mucosal Immunol. 2012 Nov;5(6):658-69. doi: 10.1038/mi.2012.39. Epub 2012 Jun 6. 2012.

Xu H, Wang X, Pahar B, Alvarez X, Rasmussen KK, Lackner AA, Veazey RS
Rapid down-regulation of gammac on T cells in early SIV infection correlates withimpairment of T-cell function.
FASEB J. 2012 Jun;26(6):2294-305. doi: 10.1096/fj.11-195180. Epub 2012 Feb 28. 2012.

2011

Addo MM, Altfeld M, Brainard DM, Rathod A, Piechocka-Trocha A, Fideli U, Mulenga J, Shutes E, Alvino DM, Hunter E, Allen SA, Walker BD
Lack of detectable HIV-1-specific CD8(+) T cell responses in ZambianHIV-1-exposed seronegative partners of HIV-1-positive individuals.
J Infect Dis. 2011 Jan 15;203(2):258-62. doi: 10.1093/infdis/jiq028. Epub 2010Dec 9. 2011.

Ansari AA, Reimann KA, Mayne AE, Takahashi Y, Stephenson ST, Wang R, Wang X, Li J, Price AA, Little DM, Zaidi M, Lyles R, Villinger F
Blocking of alpha4beta7 gut-homing integrin during acute infection leads todecreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques.
J Immunol. 2011 Jan 15;186(2):1044-59. doi: 10.4049/jimmunol.1003052. Epub 2010Dec 13. 2011.

Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, Reed P, Ribeiro RM, Pandrea I, Roques P, Silvestri G
Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1-and SIVmnd-2-infected mandrills (Mandrillus sphinx).
J Virol. 2011 Dec;85(24):13077-87. doi: 10.1128/JVI.05693-11. Epub 2011 Sep 28. 2011.

Bhakta SJ, Shang L, Prince JL, Claiborne DT, Hunter E
Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmicdomain results in a loss of Env-mediated fusion and infectivity.
Retrovirology. 2011 May 14;8:37. doi: 10.1186/1742-4690-8-37. 2011.

Bilello JP, Manrique JM, Shin YC, Lauer W, Li W, Lifson JD, Mansfield KG, Johnson RP, Desrosiers RC
Vaccine protection against simian immunodeficiency virus in monkeys usingrecombinant gamma-2 herpesvirus.
J Virol. 2011 Dec;85(23):12708-20. doi: 10.1128/JVI.00865-11. Epub 2011 Sep 7. 2011.

Bosinger SE, Sodora DL, Silvestri G
Generalized immune activation and innate immune responses in simianimmunodeficiency virus infection.
Curr Opin HIV AIDS. 2011 Sep;6(5):411-8. doi: 10.1097/COH.0b013e3283499cf6. 2011.

Budde ML, Lhost JJ, Burwitz BJ, Becker EA, Burns CM, O'Connor SL, Karl JA, Wiseman RW, Bimber BN, Zhang GL, Hildebrand W, Brusic V, O'Connor DH
Transcriptionally abundant major histocompatibility complex class I alleles arefundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses.
J Virol. 2011 Apr;85(7):3250-61. doi: 10.1128/JVI.02355-10. Epub 2011 Jan 26. 2011.

Burwitz BJ, Ende Z, Sudolcan B, Reynolds MR, Greene JM, Bimber BN, Almeida JR, Kurniawan M, Venturi V, Gostick E, Wiseman RW, Douek DC, Price DA, O'Connor DH
Simian immunodeficiency virus SIVmac239Deltanef vaccination elicits differentTat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques.
J Virol. 2011 Apr;85(7):3683-9. doi: 10.1128/JVI.02112-10. Epub 2011 Jan 26. 2011.

Burwitz BJ, Sacha JB, Reed JS, Newman LP, Norante FA, Bimber BN, Wilson NA, Watkins DI, O'Connor DH
Pyrosequencing reveals restricted patterns of CD8+ T cell escape-associatedcompensatory mutations in simian immunodeficiency virus.
J Virol. 2011 Dec;85(24):13088-96. doi: 10.1128/JVI.05650-11. Epub 2011 Oct 12. 2011.

Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC
Measuring HIV fusion mediated by envelopes from primary viral isolates.
Methods. 2011 Jan;53(1):34-8. doi: 10.1016/j.ymeth.2010.05.010. Epub 2010 Jun 8. 2011.

Chahroudi A, Meeker T, Lawson B, Ratcliffe S, Else J, Silvestri G
Mother-to-infant transmission of simian immunodeficiency virus is rare in sootymangabeys and is associated with low viremia.
J Virol. 2011 Jun;85(12):5757-63. doi: 10.1128/JVI.02690-10. Epub 2011 Mar 30. 2011.

Cheng-Mayer C, Huang Y, Gettie A, Tsai L, Ren W, Shakirzyanova M, Sina ST, Trunova N, Blanchard J, Jenkins LM, Lo Y, Schito ML, Appella E
Delay of simian human immunodeficiency virus infection and control of viralreplication in vaccinated macaques challenged in the presence of a topical microbicide.
AIDS. 2011 Sep 24;25(15):1833-41. doi: 10.1097/QAD.0b013e32834a1d94. 2011.

Colantonio AD, Bimber BN, Neidermyer WJ Jr, Reeves RK, Alter G, Altfeld M, Johnson RP, Carrington M, O'Connor DH, Evans DT
KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligandwith a Bw6 motif.
PLoS Pathog. 2011 Mar;7(3):e1001316. doi: 10.1371/journal.ppat.1001316. Epub 2011Mar 10. 2011.

Corey L, Nabel GJ, Dieffenbach C, Gilbert P, Haynes BF, Johnston M, Kublin J, Lane HC, Pantaleo G, Picker LJ, Fauci AS
HIV-1 vaccines and adaptive trial designs.
Sci Transl Med. 2011 Apr 20;3(79):79ps13. doi: 10.1126/scitranslmed.3001863. 2011.

Dahl V, Lee E, Peterson J, Spudich SS, Leppla I, Sinclair E, Fuchs D, Palmer S, Price RW
Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1infection or immunoactivation in subjects on suppressive therapy.
J Infect Dis. 2011 Dec 15;204(12):1936-45. doi: 10.1093/infdis/jir667. Epub 2011 Oct 21. 2011.

Das A, Veazey RS, Wang X, Lackner AA, Xu H, Pahar B
Simian immunodeficiency virus infection in rhesus macaques induces selectivetissue specific B cell defects in double positive CD21+CD27+ memory B cells.
Clin Immunol. 2011 Sep;140(3):223-8. doi: 10.1016/j.clim.2011.04.018. Epub 2011May 12. 2011.

Das A, Xu H, Wang X, Yau CL, Veazey RS, Pahar B
Double-positive CD21+CD27+ B cells are highly proliferating memory cells andtheir distribution differs in mucosal and peripheral tissues.
PLoS One. 2011 Jan 27;6(1):e16524. doi: 10.1371/journal.pone.0016524. 2011.

Dietrich EA, Brennan G, Ferguson B, Wiseman RW, O'Connor D, Hu SL
Variable prevalence and functional diversity of the antiretroviral restrictionfactor TRIMCyp in Macaca fascicularis.
J Virol. 2011 Oct;85(19):9956-63. doi: 10.1128/JVI.00097-11. Epub 2011 Jul 27. 2011.

Fenizia C, Keele BF, Nichols D, Cornara S, Binello N, Vaccari M, Pegu P, Robert-Guroff M, Ma ZM, Miller CJ, Venzon D, Hirsch V, Franchini G
TRIM5alpha does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposure.
J Virol. 2011 Dec;85(23):12399-409. doi: 10.1128/JVI.05707-11. Epub 2011 Sep 14. 2011.

Fofana IB, Colantonio AD, Reeves RK, Connole MA, Gillis JM, Hall LR, Sato S, Audin CR, Evans DT, Shida H, Johnson RP, Johnson WE
Flow cytometry based identification of simian immunodeficiency virus Env-specificB lymphocytes.
J Immunol Methods. 2011 Jul 29;370(1-2):75-85. doi: 10.1016/j.jim.2011.05.010.Epub 2011 Jun 13. 2011.

Ganguly S, Manicassamy S, Blackwell J, Pulendran B, Amara RR
Adenovirus type 5 induces vitamin A-metabolizing enzymes in dendritic cells andenhances priming of gut-homing CD8 T cells.
Mucosal Immunol. 2011 Sep;4(5):528-38. doi: 10.1038/mi.2011.1. Epub 2011 Feb 2. 2011.

Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, Coyne-Johnson L, Whizin N, Oswald K, Shoemaker R, Swanson T, Legasse AW, Chiuchiolo MJ, Parks CL, Axthelm MK, Nelson JA, Jarvis MA, Piatak M Jr, Lifson JD, Picker LJ
Profound early control of highly pathogenic SIV by an effector memory T-cellvaccine.
Nature. 2011 May 26;473(7348):523-7. doi: 10.1038/nature10003. Epub 2011 May 11. 2011.

Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG
A randomized, controlled trial of raltegravir intensification inantiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response.
J Infect Dis. 2011 Apr 1;203(7):960-8. doi: 10.1093/infdis/jiq138. 2011.

Hunt PW, Hatano H, Sinclair E, Lee TH, Busch MP, Martin JN, McCune JM, Deeks SG
HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers.
Clin Infect Dis. 2011 Mar 1;52(5):681-7. doi: 10.1093/cid/ciq202. Epub 2011 Jan18. 2011.

Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, KewalRamani VN, Mellors JW, Coffin JM, Ambrose Z
Genetic diversity of simian immunodeficiency virus encoding HIV-1 reversetranscriptase persists in macaques despite antiretroviral therapy.
J Virol. 2011 Jan;85(2):1067-76. doi: 10.1128/JVI.01701-10. Epub 2010 Nov 17. 2011.

Kwa S, Kannanganat S, Nigam P, Siddiqui M, Shetty RD, Armstrong W, Ansari A, Bosinger SE, Silvestri G, Amara RR
Plasmacytoid dendritic cells are recruited to the colorectum and contribute toimmune activation during pathogenic SIV infection in rhesus macaques.
Blood. 2011 Sep 8;118(10):2763-73. doi: 10.1182/blood-2011-02-339515. Epub 2011Jun 21. 2011.

Lai L, Kwa S, Kozlowski PA, Montefiori DC, Ferrari G, Johnson WE, Hirsch V, Villinger F, Chennareddi L, Earl PL, Moss B, Amara RR, Robinson HL
Prevention of infection by a granulocyte-macrophage colony-stimulating factorco-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine.
J Infect Dis. 2011 Jul 1;204(1):164-73. doi: 10.1093/infdis/jir199. 2011.

Lakhashe SK, Velu V, Sciaranghella G, Siddappa NB, Dipasquale JM, Hemashettar G, Yoon JK, Rasmussen RA, Yang F, Lee SJ, Montefiori DC, Novembre FJ, Villinger F, Amara RR, Kahn M, Hu SL, Li S, Li Z, Frankel FR, Robert-Guroff M, Johnson WE, Lieberman J, Ruprecht RM
Prime-boost vaccination with heterologous live vectors encoding SIV gag andmultimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.
Vaccine. 2011 Aug 5;29(34):5611-22. doi: 10.1016/j.vaccine.2011.06.017. Epub 2011Jul 14. 2011.

Lakhashe SK, Wang W, Siddappa NB, Hemashettar G, Polacino P, Hu SL, Villinger F, Else JG, Novembre FJ, Yoon JK, Lee SJ, Montefiori DC, Ruprecht RM, Rasmussen RA
Vaccination against heterologous R5 clade C SHIV: prevention of infection andcorrelates of protection.
PLoS One. 2011;6(7):e22010. doi: 10.1371/journal.pone.0022010. Epub 2011 Jul 20. 2011.

Lasaro MO, Haut LH, Zhou X, Xiang Z, Zhou D, Li Y, Giles-Davis W, Li H, Engram JC, Dimenna LJ, Bian A, Sazanovich M, Parzych EM, Kurupati R, Small JC, Wu TL, Leskowitz RM, Klatt NR, Brenchley JM, Garber DA, Lewis M, Ratcliffe SJ, Betts MR, Silvestri G, Ertl HC
Vaccine-induced T cells provide partial protection against high-dose rectalSIVmac239 challenge of rhesus macaques.
Mol Ther. 2011 Feb;19(2):417-26. doi: 10.1038/mt.2010.238. Epub 2010 Nov 16. 2011.

Li C, Zhang X, Komery A, Li Y, Novembre FJ, Herndon JG
Longitudinal diffusion tensor imaging and perfusion MRI investigation in amacaque model of neuro-AIDS: a preliminary study.
Neuroimage. 2011 Sep 1;58(1):286-92. doi: 10.1016/j.neuroimage.2011.05.068. Epub 2011 Jun 1. 2011.

Liao Q, Guo H, Tang M, Touzjian N, Lerche NW, Lu Y, Yee JL
Simultaneous detection of antibodies to five simian viruses in nonhuman primates using recombinant viral protein based multiplex microbead immunoassays.
J Virol Methods. 2011 Dec;178(1-2):143-52. doi: 10.1016/j.jviromet.2011.09.004.Epub 2011 Sep 17. 2011.

Lynch RM, Rong R, Boliar S, Sethi A, Li B, Mulenga J, Allen S, Robinson JE, Gnanakaran S, Derdeyn CA
The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter.
J Virol. 2011 Jan;85(2):905-15. doi: 10.1128/JVI.02006-10. Epub 2010 Oct 27. 2011.

Malherbe DC, Doria-Rose NA, Misher L, Beckett T, Puryear WB, Schuman JT, Kraft Z, O'Malley J, Mori M, Srivastava I, Barnett S, Stamatatos L, Haigwood NL
Sequential immunization with a subtype B HIV-1 envelope quasispecies partiallymimics the in vivo development of neutralizing antibodies.
J Virol. 2011 Jun;85(11):5262-74. doi: 10.1128/JVI.02419-10. Epub 2011 Mar 23. 2011.

Marthas ML, Van Rompay KK, Abbott Z, Earl P, Buonocore-Buzzelli L, Moss B, Rose NF, Rose JK, Kozlowski PA, Abel K
Partial efficacy of a VSV-SIV/MVA-SIV vaccine regimen against oral SIV challenge in infant macaques.
Vaccine. 2011 Apr 12;29(17):3124-37. doi: 10.1016/j.vaccine.2011.02.051. Epub2011 Mar 4. 2011.

Mehra S, Golden NA, Dutta NK, Midkiff CC, Alvarez X, Doyle LA, Asher M, Russell-Lodrigue K, Monjure C, Roy CJ, Blanchard JL, Didier PJ, Veazey RS, Lackner AA, Kaushal D
Reactivation of latent tuberculosis in rhesus macaques by coinfection with simianimmunodeficiency virus.
J Med Primatol. 2011 Aug;40(4):233-43. doi: 10.1111/j.1600-0684.2011.00485.x. 2011.

Merino A, Malhotra R, Morton M, Mulenga J, Allen S, Hunter E, Tang J, Kaslow RA
Impact of a functional KIR2DS4 allele on heterosexual HIV-1 transmission amongdiscordant Zambian couples.
J Infect Dis. 2011 Feb 15;203(4):487-95. doi: 10.1093/infdis/jiq075. Epub 2011Jan 7. 2011.

Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure HM, O'Neil SP, Kaur A
Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection.
J Immunol. 2011 May 1;186(9):5151-61. doi: 10.4049/jimmunol.1004110. Epub 2011Mar 25. 2011.

Mohr EL, Murthy KK, McLinden JH, Xiang J, Stapleton JT
The natural history of non-human GB virus C in captive chimpanzees.
J Gen Virol. 2011 Jan;92(Pt 1):91-100. doi: 10.1099/vir.0.026088-0. Epub 2010 Sep22. 2011.

Moldt B, Schultz N, Dunlop DC, Alpert MD, Harvey JD, Evans DT, Poignard P, Hessell AJ, Burton DR
A panel of IgG1 b12 variants with selectively diminished or enhanced affinity forFcgamma receptors to define the role of effector functions in protection against HIV.
J Virol. 2011 Oct;85(20):10572-81. doi: 10.1128/JVI.05541-11. Epub 2011 Aug 17. 2011.

Molina PE, Amedee A, LeCapitaine NJ, Zabaleta J, Mohan M, Winsauer P, Vande Stouwe C
Cannabinoid neuroimmune modulation of SIV disease.
J Neuroimmune Pharmacol. 2011 Dec;6(4):516-27. doi: 10.1007/s11481-011-9301-8.Epub 2011 Aug 10. 2011.

Mudd PA, Ericsen AJ, Price AA, Wilson NA, Reimann KA, Watkins DI
Reduction of CD4+ T cells in vivo does not affect virus load in macaque elitecontrollers.
J Virol. 2011 Jul;85(14):7454-9. doi: 10.1128/JVI.00738-11. Epub 2011 May 18. 2011.

Mudd PA, Ericsen AJ, Walsh AD, Leon EJ, Wilson NA, Maness NJ, Friedrich TC, Watkins DI
CD8+ T cell escape mutations in simian immunodeficiency virus SIVmac239 causefitness defects in vivo, and many revert after transmission.
J Virol. 2011 Dec;85(23):12804-10. doi: 10.1128/JVI.05841-11. Epub 2011 Sep 28. 2011.

Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, Collman RG, Apetrei C, Pandrea I, Else J, Munch J, Kirchhoff F, Davenport MP, Brenchley JM, Silvestri G
Low levels of SIV infection in sooty mangabey central memory CD(4)(+) T cells areassociated with limited CCR5 expression.
Nat Med. 2011 Jun 26;17(7):830-6. doi: 10.1038/nm.2395. 2011.

Palermo RE, Patterson LJ, Aicher LD, Korth MJ, Robert-Guroff M, Katze MG
Genomic analysis reveals pre- and postchallenge differences in a rhesus macaqueAIDS vaccine trial: insights into mechanisms of vaccine efficacy.
J Virol. 2011 Jan;85(2):1099-116. doi: 10.1128/JVI.01522-10. Epub 2010 Nov 10. 2011.

Ratai EM, Pilkenton S, He J, Fell R, Bombardier JP, Joo CG, Lentz MR, Kim WK, Burdo TH, Autissier P, Annamalai L, Curran E, O'Neil SP, Westmoreland SV, Williams KC, Masliah E, Gilberto Gonzalez R
CD8+ lymphocyte depletion without SIV infection does not produce metabolicchanges or pathological abnormalities in the rhesus macaque brain.
J Med Primatol. 2011 Oct;40(5):300-9. doi: 10.1111/j.1600-0684.2011.00475.x. Epub2011 Apr 4. 2011.

Reynolds MR, Sacha JB, Weiler AM, Borchardt GJ, Glidden CE, Sheppard NC, Norante FA, Castrovinci PA, Harris JJ, Robertson HT, Friedrich TC, McDermott AB, Wilson NA, Allison DB, Koff WC, Johnson WE, Watkins DI
The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simianimmunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge.
J Virol. 2011 Sep;85(18):9637-40. doi: 10.1128/JVI.05074-11. Epub 2011 Jul 6. 2011.

Rotger M, Dalmau J, Rauch A, McLaren P, Bosinger SE, Martinez R, Sandler NG, Roque A, Liebner J, Battegay M, Bernasconi E, Descombes P, Erkizia I, Fellay J, Hirschel B, Miro JM, Palou E, Hoffmann M, Massanella M, Blanco J, Woods M, Gunthard HF, de Bakker P, Douek DC, Silvestri G, Martinez-Picado J, Telenti A
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection andSIV infection in sooty mangabey and rhesus macaque.
J Clin Invest. 2011 Jun;121(6):2391-400. doi: 10.1172/JCI45235. Epub 2011 May 9. 2011.

Santos RV, Lin KC, Mansfield K, Wachtman LM
Specific pathogen-free status alters immunophenotype in rhesus macaques:implications for the study of simian immunodeficiency virus.
AIDS Res Hum Retroviruses. 2011 Oct;27(10):1033-42. doi: 10.1089/AID.2010.0155.Epub 2011 Apr 3. 2011.

Santosuosso M, Righi E, Hill ED, Leblanc PR, Kodish B, Mylvaganam HN, Siddappa NB, Stevceva L, Hu SL, Ghebremichael M, Chenine AL, Hovav AH, Ruprecht RM, Poznansky MC
R5-SHIV induces multiple defects in T cell function during early infection ofrhesus macaques including accumulation of T reg cells in lymph nodes.
PLoS One. 2011 Apr 5;6(4):e18465. doi: 10.1371/journal.pone.0018465. 2011.

Schnell G, Joseph S, Spudich S, Price RW, Swanstrom R
HIV-1 replication in the central nervous system occurs in two distinct celltypes.
PLoS Pathog. 2011 Oct;7(10):e1002286. doi: 10.1371/journal.ppat.1002286. Epub2011 Oct 6. 2011.

Siddappa NB, Hemashettar G, Shanmuganathan V, Semenya AA, Sweeney ED, Paul KS, Lee SJ, Secor WE, Ruprecht RM
Schistosoma mansoni enhances host susceptibility to mucosal but not intravenouschallenge by R5 Clade C SHIV.
PLoS Negl Trop Dis. 2011 Aug;5(8):e1270. doi: 10.1371/journal.pntd.0001270. Epub 2011 Aug 2. 2011.

Siddappa NB, Hemashettar G, Wong YL, Lakhashe S, Rasmussen RA, Watkins JD, Novembre FJ, Villinger F, Else JG, Montefiori DC, Ruprecht RM
Development of a tier 1 R5 clade C simian-human immunodeficiency virus as a tool to test neutralizing antibody-based immunoprophylaxis.
J Med Primatol. 2011 Apr;40(2):120-8. doi: 10.1111/j.1600-0684.2010.00454.x. Epub2010 Nov 2. 2011.

Song W, He D, Brill I, Malhotra R, Mulenga J, Allen S, Hunter E, Tang J, Kaslow RA
Disparate associations of HLA class I markers with HIV-1 acquisition and control of viremia in an African population.
PLoS One. 2011;6(8):e23469. doi: 10.1371/journal.pone.0023469. Epub 2011 Aug 17. 2011.

Southwood S, Solomon C, Hoof I, Rudersdorf R, Sidney J, Peters B, Wahl A, Hawkins O, Hildebrand W, Mothe BR, Sette A
Functional analysis of frequently expressed Chinese rhesus macaque MHC class Imolecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities.
Immunogenetics. 2011 May;63(5):275-90. doi: 10.1007/s00251-010-0502-8. Epub 2011 Jan 28. 2011.

Spudich S, Gisslen M, Hagberg L, Lee E, Liegler T, Brew B, Fuchs D, Tambussi G, Cinque P, Hecht FM, Price RW
Central nervous system immune activation characterizes primary humanimmunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden.
J Infect Dis. 2011 Sep 1;204(5):753-60. doi: 10.1093/infdis/jir387. 2011.

Stansell E, Canis K, Haslam SM, Dell A, Desrosiers RC
Simian immunodeficiency virus from the sooty mangabey and rhesus macaque ismodified with O-linked carbohydrate.
J Virol. 2011 Jan;85(1):582-95. doi: 10.1128/JVI.01871-10. Epub 2010 Oct 20. 2011.

Tang J, Cormier E, Gilmour J, Price MA, Prentice HA, Song W, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Amornkul PN, Allen S, Hunter E, Kaslow RA
Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes.
J Virol. 2011 Sep;85(17):8894-902. doi: 10.1128/JVI.00439-11. Epub 2011 Jun 29. 2011.

Tasca S, Zhuang K, Gettie A, Knight H, Blanchard J, Westmoreland S, Cheng-Mayer C
Effect of B-cell depletion on coreceptor switching in R5 simian-humanimmunodeficiency virus infection of rhesus macaques.
J Virol. 2011 Apr;85(7):3086-94. doi: 10.1128/JVI.02150-10. Epub 2011 Jan 19. 2011.

Thippeshappa R, Polacino P, Yu Kimata MT, Siwak EB, Anderson D, Wang W, Sherwood L, Arora R, Wen M, Zhou P, Hu SL, Kimata JT
Vif substitution enables persistent infection of pig-tailed macaques by humanimmunodeficiency virus type 1.
J Virol. 2011 Apr;85(8):3767-79. doi: 10.1128/JVI.02438-10. Epub 2011 Feb 2. 2011.

Tsibris AM, Pal U, Schure AL, Veazey RS, Kunstman KJ, Henrich TJ, Klasse PJ, Wolinsky SM, Kuritzkes DR, Moore JP
SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does notinvolve resistant viruses.
PLoS One. 2011;6(12):e28047. doi: 10.1371/journal.pone.0028047. Epub 2011 Dec 2. 2011.

Vinton C, Klatt NR, Harris LD, Briant JA, Sanders-Beer BE, Herbert R, Woodward R, Silvestri G, Pandrea I, Apetrei C, Hirsch VM, Brenchley JM
CD4-like immunological function by CD4- T cells in multiple natural hosts ofsimian immunodeficiency virus.
J Virol. 2011 Sep;85(17):8702-8. doi: 10.1128/JVI.00332-11. Epub 2011 Jun 29. 2011.

Wang X, Xu H, Alvarez X, Pahar B, Moroney-Rasmussen T, Lackner AA, Veazey RS
Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques.
PLoS One. 2011;6(11):e27207. doi: 10.1371/journal.pone.0027207. Epub 2011 Nov 9. 2011.

Watkins JD, Siddappa NB, Lakhashe SK, Humbert M, Sholukh A, Hemashettar G, Wong YL, Yoon JK, Wang W, Novembre FJ, Villinger F, Ibegbu C, Patel K, Corti D, Agatic G, Vanzetta F, Bianchi S, Heeney JL, Sallusto F, Lanzavecchia A, Ruprecht RM
An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cellimmunity in macaques mucosally challenged with an R5 clade C SHIV.
PLoS One. 2011 Mar 31;6(3):e18207. doi: 10.1371/journal.pone.0018207. 2011.

Westmoreland SV, Annamalai L, Lentz MR, Ratai EM, Assaf B, Boisvert K, Huynh T, Vallender EJ, Miller GM, Madras BK, Gonzalez RG
Growth-associated protein-43 and ephrin B3 induction in the brain of adultSIV-infected rhesus macaques.
J Neurovirol. 2011 Oct;17(5):455-68. doi: 10.1007/s13365-011-0047-0. Epub 2011Jul 26. 2011.

Xu H, Wang X, Morici LA, Pahar B, Veazey RS
Early divergent host responses in SHIVsf162P3 and SIVmac251 infected macaquescorrelate with control of viremia.
PLoS One. 2011 Mar 25;6(3):e17965. doi: 10.1371/journal.pone.0017965. 2011.

Zhuang K, Finzi A, Tasca S, Shakirzyanova M, Knight H, Westmoreland S, Sodroski J, Cheng-Mayer C
Adoption of an 'open' envelope conformation facilitating CD4 binding andstructural remodeling precedes coreceptor switch in R5 SHIV-infected macaques.
PLoS One. 2011;6(7):e21350. doi: 10.1371/journal.pone.0021350. Epub 2011 Jul 8. 2011.

2010

Kirmaier A, Wu F, Newman RM, Hall LR, Morgan JS, O'Connor S, Marx PA, Meythaler M, Goldstein S, Buckler-White A, Kaur A, Hirsch VM, Johnson WE
TRIM5 suppresses cross-species transmission of a primate immunodeficiency virusand selects for emergence of resistant variants in the new species.
PLoS Biol. 2010 Aug 24;8(8). doi: 10.1371/journal.pbio.1000462. 2010.

Maness NJ, Walsh AD, Piaskowski SM, Furlott J, Kolar HL, Bean AT, Wilson NA, Watkins DI
CD8+ T cell recognition of cryptic epitopes is a ubiquitous feature of AIDS virusinfection.
J Virol. 2010 Nov;84(21):11569-74. doi: 10.1128/JVI.01419-10. Epub 2010 Aug 25. 2010.

Ng CT, Jaworski JP, Jayaraman P, Sutton WF, Delio P, Kuller L, Anderson D, Landucci G, Richardson BA, Burton DR, Forthal DN, Haigwood NL
Passive neutralizing antibody controls SHIV viremia and enhances B cell responsesin infant macaques.
Nat Med. 2010 Oct;16(10):1117-9. doi: 10.1038/nm.2233. Epub 2010 Oct 3. 2010.

Wang X, Xu H, Pahar B, Alvarez X, Green LC, Dufour J, Moroney-Rasmussen T, Lackner AA, Veazey RS
Simian immunodeficiency virus selectively infects proliferating CD4+ T cells inneonatal rhesus macaques.
Blood. 2010 Nov 18;116(20):4168-74. doi: 10.1182/blood-2010-03-273482. Epub 2010 Aug 17. 2010.

Worobey M, Telfer P, Souquiere S, Hunter M, Coleman CA, Metzger MJ, Reed P, Makuwa M, Hearn G, Honarvar S, Roques P, Apetrei C, Kazanji M, Marx PA
Island biogeography reveals the deep history of SIV.
Science. 2010 Sep 17;329(5998):1487. doi: 10.1126/science.1193550. 2010.

2009

Liu J, O'Brien KL, Lynch DM, Simmons NL, La Porte A, Riggs AM, Abbink P, Coffey RT, Grandpre LE, Seaman MS, Landucci G, Forthal DN, Montefiori DC, Carville A, Mansfield KG, Havenga MJ, Pau MG, Goudsmit J, Barouch DH
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys.
Nature. 2009 Jan 1;457(7225):87-91. doi: 10.1038/nature07469. Epub 2008 Nov 9. 2009.

Sacha JB, Giraldo-Vela JP, Buechler MB, Martins MA, Maness NJ, Chung C, Wallace LT, Leon EJ, Friedrich TC, Wilson NA, Hiraoka A, Watkins DI
Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication ininfected macrophages early after infection.
Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9791-6. doi:10.1073/pnas.0813106106. Epub 2009 May 28. 2009.

Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, Vanderford TH, Chennareddi L, Silvestri G, Freeman GJ, Ahmed R, Amara RR
Enhancing SIV-specific immunity in vivo by PD-1 blockade.
Nature. 2009 Mar 12;458(7235):206-10. doi: 10.1038/nature07662. Epub 2008 Dec 10. 2009.