Breakthrough Discoveries from the Wisconsin National Primate Research Center

Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, Mohns MS, Breitbach ME, Rasheed MN, Newman CM, Gellerup DD, Moncla LH, Post J, Schultz-Darken N, Schotzko ML, Hayes JM, Eudailey JA, Moody MA, Permar SR, O'Connor SL, Rakasz EG, Simmons HA, Capuano S, Golos TG, Osorio JE, Friedrich TC, O'Connor DH.
A rhesus macaque model of Asian-lineage Zika virus infection.
Nat Commun. 2016 Jun 28;7:12204. doi: 10.1038/ncomms12204. PubMed PMID: 27352279;PubMed Central PMCID: PMC4931337.

Colman RJ, Beasley TM, Kemnitz JW, Johnson SC, Weindruch R, Anderson RM.
Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys.
Nat Commun. 2014 Apr 1;5:3557. doi: 10.1038/ncomms4557. PubMed PMID: 24691430; PubMed Central PMCID: PMC3988801.

Fox AS, Oler JA, Shackman AJ, Shelton SE, Raveendran M, McKay DR, Converse AK, Alexander A, Davidson RJ, Blangero J, Rogers J, Kalin NH.
Intergenerational neural mediators of early-life anxious temperament.
Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9118-22. doi: 10.1073/pnas.1508593112. PubMed PMID: 26150480; PubMed Central PMCID: PMC4517228.

Emborg ME, Liu Y, Xi J, Zhang X, Yin Y, Lu J, Joers V, Swanson C, Holden JE, Zhang SC.
Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain.
Cell Rep. 2013 Mar 28;3(3):646-50. doi: 10.1016/j.celrep.2013.02.016. PubMed PMID: 23499447; PubMed Central PMCID: PMC3633566.

Mudd PA, Martins MA, Ericsen AJ, Tully DC, Power KA, Bean AT, Piaskowski SM, Duan L, Seese A, Gladden AD, Weisgrau KL, Furlott JR, Kim YI, Veloso de Santana MG, Rakasz E, Capuano S 3rd, Wilson NA, Bonaldo MC, Galler R, Allison DB, Piatak M Jr, Haase AT, Lifson JD, Allen TM, Watkins DI.
Vaccine-induced CD8+ T cells control AIDS virus replication.
Nature. 2012 Nov 1;491(7422):129-33. doi: 10.1038/nature11443. PubMed PMID: 23023123; PubMed Central PMCID: PMC3883109.

Terasawa E, Kurian JR, Keen KL, Shiel NA, Colman RJ, Capuano SV.
Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys.
Endocrinology. 2012 Apr;153(4):1696-705. doi: 10.1210/en.2011-1970. PubMed PMID: 22315448; PubMed Central PMCID: PMC3320255.

Kenealy BP, Kapoor A, Guerriero KA, Keen KL, Garcia JP, Kurian JR, Ziegler TE, Terasawa E.
Neuroestradiol in the hypothalamus contributes to the regulation of gonadotropin releasing hormone release.
J Neurosci. 2013 Dec 4;33(49):19051-9. doi: 10.1523/JNEUROSCI.3878-13.2013. PMID: 24305803. PMCID: PMC3850033.

Alisch RS, Chopra P, Fox AS, Chen K, White AT, Roseboom PH, Keles S, Kalin NH.
Differentially methylated plasticity genes in the amygdala of young primates are linked to anxious temperament, an at risk phenotype for anxiety and depressive disorders.
J Neurosci. 2014 Nov 19;34(47):15548-56. doi: 10.1523/JNEUROSCI.3338-14.2014. PMID: 25411484. PMCID: PMC4236392.